ORS Musculoskeletal Biology Workshop at Zermatt

采尔马特 ORS 肌肉骨骼生物学研讨会

• 批准号: 10753967
• 负责人: ALEXANDER G ROBLING
• 金额: $ 1.5万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10753967
• 关键词: Address; Award; Basic Science; Biology; Biomechanics; Bone Diseases; Cartilage Diseases; Cells; Cities; Clinical; Clinical Investigator; Communities; Degenerative polyarthritis; Development; Disease; Educational workshop; Electronic Mail; Engineering; Faculty; Feedback; Goals; Idaho; Image; Interdisciplinary Communication; Link; Location; Molecular; Molecular Target; Musculoskeletal; Musculoskeletal Diseases; Myopathy; Orthopedics; Osteoclasts; Pathogenesis; Physicians; Prevention; Problem Solving; Process; Public Health; Request for Applications; Research; Research Personnel; Resort; Scientific Advances and Accomplishments; Scientist; Senior Scientist; Societies; Sodium Chloride; Students; Therapeutic; Time; Tissues; Utah; Work; bone; career development; clinical practice; improved; insight; interdisciplinary collaboration; meetings; multidisciplinary; public health relevance; response; skeletal disorder; skeletal stem cell; student training; symposium; tool; web site

Description This application requests support for the 50th annual meeting of the ORS Musculoskeletal Biology Workshop, which had been held at Sun Valley, Idaho, for the past 20+ years. In 2022 the Workshop moved to the Utah Rockies, just outside Salt Lake City. The 2023 workshop will be held in Midland, Utah at the Zermatt Resort, from July 21-25, 2023. The Workshop was moved to the new location in response to feedback from attendees over the past several years, who expressed a desire to have the meeting at a venue that was less expensive and easier to get to. We have achieved both of those improvements with the new location. The conference itself will maintain the same spirit it has enjoyed for several decades: it emphasizes active participation of junior faculty and students; promotes interdisciplinary communication; and is unusual in that discussion time equals or exceeds time allotted for formal presentation. The goals of the Workshop are to (1) work toward a multidisciplinary basic and clinical synthesis of molecular, tissue and biomechanical processes in musculoskeletal tissues that help us to understand the pathogenesis of bone, muscle, and cartilage disease as well as its prevention and treatment; (2) apply basic science concepts to clinical problems; develop a dialogue between basic and clinical investigators that leads to interdisciplinary collaboration; (3) identify significant problems in musculoskeletal disease, and identify experimental approaches that provide solutions to them and (4) provide a forum for student training and the opportunity in a small group setting for junior scientists to talk with more senior scientists. A partnership between the Workshop and the Orthopaedic Research Society (ORS) provides maximum visibility through broadcast emails and links on the ORS website. This year we continue our newly instituted focus on problem solving, with the theme for the Workshop being “Musculoskeletal cells: identity, targeting, stimulation, and manipulation for therapeutic gain.” Six sessions address relevant and significant current problems, including current challenges with rare skeletal disease, recent breakthroughs in our understanding of the biology of osteoarthritis, progress in bone-targeting molecular tools for delivery of therapeutics, new insights into osteoclast origin and fate, advances in skeletal stem cells, and the intersection of mechanobiology and imaging. A notable feature of this Workshop is that it is becoming a truly musculoskeletal workshop, considering problems of musculoskeletal conditions beyond bone, though the major focus remains bone. Opportunities are provided for junior investigators to interact with more senior investigators. Two Career Development sessions specifically geared toward young investigators will be conducted. Ten ASBMR/Frost Young Investigator Awardees will present their work from the podium. Ten or more Jee Young Investigator Awards will also be distributed to increase young investigator attendance and participation.

描述 本申请请求支持 ORS 肌肉骨骼生物学研讨会第 50 届年会， 过去 20 多年一直在爱达荷州太阳谷举办，2022 年研讨会搬到了犹他州。 盐湖城郊外的落基山脉 2023 年研讨会将在犹他州米德兰的采尔马特度假村举行。 2023年7月21日至25日。根据与会者的反馈，研讨会搬至新地点 过去几年，谁表示希望在更便宜的地点举行会议 会议的新地点使我们都实现了这些改进。 它本身将保持几十年来所享有的相同精神：它强调初级者的积极参与 教师和学生之间的交流；并且不同寻常的是，讨论时间是平等的。 或超出正式演示的时间 研讨会的目标是 (1) 努力实现 分子、组织和生物力学过程的多学科基础和临床综合 肌肉骨骼组织帮助我们了解骨、肌肉和软骨疾病的发病机制 及其预防和治疗；（2）将基本科学概念应用于临床问题； (3) 识别显着性 肌肉骨骼疾病的问题，并确定为这些问题提供解决方案的实验方法 (4) 为学生培训提供论坛，并为年轻科学家提供小组讨论的机会 与更多资深科学家合作。 (ORS) 今年我们通过广播电子邮件和 ORS 网站上的链接提供最大的可见性。 继续我们新设立的解决问题的重点，研讨会的主题是 “肌肉骨骼细胞：识别、靶向、刺激和操纵以获得治疗效果。” 解决当前相关的重大问题，包括当前罕见骨骼疾病的挑战， 最近我们对骨关节炎生物学的理解取得了突破，骨靶向分子的进展 提供治疗的工具、对破骨细胞起源和命运的新见解、骨骼干细胞的进展、 本次研讨会的一个显着特点是它正在成为机械生物学和成像的交叉点。 一个真正的肌肉骨骼研讨会，考虑骨骼以外的肌肉骨骼状况问题 主要重点仍然是为初级研究人员提供与高级研究人员互动的机会。 将举办两场专门针对年轻研究者的职业发展课程。 十名 ASBMR/Frost 青年研究员获奖者将在讲台上展示他们的工作。 还将颁发更多的 Jee Young 研究员奖，以增加年轻研究员的出席率和 参与。