Research Education Core

研究教育核心

基本信息

批准号：
10684071
负责人：
Gene Gabriel Gurkoff
金额：
$ 13.6万
依托单位：
UNIVERSITY OF CALIFORNIA AT DAVIS
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-01 至 2027-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10684071
关键词：
Academia Acute Address Animal Disease Models Area Basic Science Biometry Chronic Clinical Trials Communities Complex Development Diverse Workforce Drug Screening Educational Activities Educational workshop Effectiveness Emergency response Environment Evaluation Exposure to Faculty Feedback Fostering Future Generations Goals Government Growth Human Resources Image Industry Innovative Therapy Institution Interdisciplinary Study Intoxication Knowledge Laboratories Learning Medical Students Mentors Mission Neurologic Neurology Neurosciences Organophosphates Outcome Participant Patients Pharmaceutical Chemistry Pharmacology Pharmacology and Toxicology Postdoctoral Fellow Preclinical Testing Process Research Research Activity Research Personnel Research Project Summaries Research Training Resources Scientist Therapeutic Toxicology Training Translational Research Underrepresented Populations United States National Institutes of Health Work career chemical threat cohort design disadvantaged background drug development drug discovery education research effectiveness evaluation emergency preparedness equity, diversity, and inclusion experience graduate student improved instructor lectures medical countermeasure meetings member nervous system disorder neurotoxicology next generation outreach programs recruit responsible research conduct role model skills socioeconomic disadvantage success undergraduate student

项目摘要

Project Summary – Research Education Core (REC) The training of future leaders in the development of medical countermeasures for chemical threat agents is critical to the success of the CounterACT program and to national emergency response and preparedness efforts. The overall mission of the Research Education Core (REC) is to create a diverse array of human resources capable of conducting team-based interdisciplinary research focused on addressing the complex problems posed by chemical threat agents. Advanced training in pharmacology, toxicology, neuroscience, and drug discovery will be provided to a diverse generation of researchers, more specifically, technicians, medical and graduate students, postdoctoral fellows, and/or early stage investigators within and outside the UC Davis CounterACT Center. Accordingly, the REC will interact with all Cores and Projects of the Center. A major emphasis will be enhancing the diversity, and recruitment of trainees and mentors from underrepresented and socioeconomically disadvantaged backgrounds into the Center. The educational research environment at UC Davis is well suited for the CounterACT Center. UC Davis is a national leader in pharmacology and toxicology, and CounterACT faculty have expertise in fundamental pharmacology, toxicology, medicinal chemistry, drug screening, mechanistic target identification, animal models of disease, advanced imaging, biostatistics as well as preclinical testing and participation in clinical trials. The REC will facilitate the transfer of this knowledge to trainees and promote the advancement of trainees’ careers by providing opportunities to be mentored by and learn from both internal and external scientists with expertise relevant to the CounterACT mission. The REC has three main objectives: (1) Develop skill sets necessary for the study of toxicology, pharmacology, drug discovery, neuroscience, and neurological disorders related to chemical threat agents. First, hands- on interdisciplinary and collaborative research training primarily in the laboratories of the Project and Core Leaders will be provided. Second, specialized didactic training in areas relevant to the Center’s mission will be accomplished via workshops, seminars, and specialized coursework. (2) Enhance the recruitment of graduate students and faculty from underrepresented backgrounds into the UC Davis CounterACT Center by leveraging well established undergraduate, graduate, and faculty STEM-related recruiting and retention programs on campus. (3) Evaluate the activities of the REC to assess effectiveness and identify areas for improvement. By fulfilling these objectives, the REC will accomplish its goal of developing a diverse group of scientists with broader understanding of the concepts, challenges, and opportunities in drug discovery and development of medical countermeasures of chemical threat agents.

项目摘要 – 研究教育核心 (REC) 对化学威胁剂医疗对策开发未来领导者的培训是对于 CounterACT 计划的成功以及国家应急响应和准备工作至关重要研究教育核心（REC）的总体使命是培养多样化的人才能够进行基于团队的跨学科研究的资源，重点关注解决复杂的问题化学威胁剂造成的问题。药理学、毒理学、神经科学和化学方面的高级培训。药物发现将提供给不同世代的研究人员，更具体地说，技术人员、医疗人员以及加州大学戴维斯分校内外的研究生、博士后研究员和/或早期研究人员 CounterACT 中心。因此，REC 将与该中心的所有核心和项目进行互动。重点将是增强多样性，并从代表性不足和社会经济弱势背景进入中心。加州大学戴维斯分校的教育研究环境非常适合加州大学戴维斯分校的 CounterACT 中心。药理学和毒理学领域的国家领导者，CounterACT 教师拥有基础知识方面的专业知识药理学、毒理学、药物化学、药物筛选、机制靶标识别、动物模型疾病、先进成像、生物统计学以及临床前测试和参与临床试验。 REC 将促进这些知识向学员的传授，并促进学员的职业发展通过提供接受具有专业知识的内部和外部科学家的指导和学习的机会与 CounterACT 任务相关。 REC 有三个主要目标：(1) 培养毒理学、药理学研究所需的技能，首先，与化学威胁剂相关的药物发现、神经科学和神经系统疾病。主要在项目和核心实验室进行跨学科和协作研究培训其次，将提供与中心使命相关领域的专门教学培训。（二）加大毕业生引进力度通过利用来自弱势背景的学生和教师进入加州大学戴维斯分校 CounterACT 中心完善的本科生、研究生和教职员工与 STEM 相关的招聘和保留计划 (3) 评估 REC 的活动，以评估有效性并确定需要改进的领域。通过实现这些目标，REC 将实现培养多元化科学家群体的目标对药物发现和开发的概念、挑战和机遇有更广泛的了解化学威胁剂的医疗对策。