Support for Vector Biology Training for Sustainable Control of Vector Borne diseases in East Africa

支持媒介生物学培训以可持续控制东非媒介传播疾病

• 批准号: 10675897
• 负责人: Serap AKSOY
• 金额: $ 25.04万
• 依托单位: BIOTECHNOLOGY RESEARCH INSTITUTE-KALRO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2027-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10675897
• 关键词: Address; Administrator; Adoption; Africa; Africa South of the Sahara; African; Agriculture; Animals; Award; Bioethics; Biology; Biotechnology; Clinical; Consultations; Country; Disease; Ecology; Education; Educational workshop; Environmental Health; Epidemiology; Faculty; Genomics; Human; Institution; Kenya; Knowledge; Laboratories; Leadership; Livestock; Manuscripts; Medical Research; Mentorship; Output; Participant; Persons; Physiology; Policy Maker; Population Genetics; Postdoctoral Fellow; Practice Management; Preparation; Public Health; Public Health Schools; Research; Research Institute; Research Personnel; Science; Scientist; Tanzania; Teacher Professional Development; Technology; Training; Uganda; Universities; Vector-transmitted infectious disease; burden of illness; career; data management; editorial; empowerment; evidence base; innovation; institutional capacity; low and middle-income countries; mathematical model; neglected tropical diseases; next generation; peer; programs; research and development; skills; training opportunity; vector; vector control; vector management strategies; vector-borne; virtual; webinar

Vector-borne and neglected tropical diseases (VBDs and NTDs, respectively) are endemic and emerging threats in sub-Saharan Africa (sSA). In this renewal application, scientists from Kenya Agricultural and Livestock Research Organization, Biotechnology Research Institute (BioRI-KALRO), and Yale School of Public Health (YSPH) will partner with Kenya Medical Research Institute (KEMRI), Gulu University (GU) and Vector and Vector-Borne Diseases Institute (VVBDI) and their peers in Kenya, Uganda and Tanzania with support of the East African Science and Technology Commission (EASTECO) to strengthen Vector Biology (VB) education and research capacity in order to advance vector control applications and reduce disease burden in East Africa. Our specific objectives are to: Aim 1) Empower early-career researchers in East Africa. Our training will target early-career scientists, including post-doctoral scholars and junior level faculty. We will transfer knowledge necessary to advance the state-of-the-art laboratory and field research skills, mathematical modeling and data management within broad fields of vector physiology, ecology, population genetics/genomics and epidemiology. We will establish regional network(s) of early-career researchers in LMIC institutions to support the next-generation of researchers and field practitioners and policy makers. Our program will prepare trainees with necessary skills to establish independent research programs, and to advise on sustainable and evidence-based strategies for in-country VC and disease elimination programs, and promote public discussions and consultations to advance downstream delivery capacity of innovative and integrated human, animal and environmental health VC technologies. Aim 2) Develop leadership and institutional capacity to disseminate knowledge on innovative VC applications. We will offer in-person and/or virtual training and mentorship opportunities in bioethics, proficient clinical and laboratory practices, vector management and biosafety to early-career scientists from LMIC institutions. We will also train faculties in manuscript preparation, grantsmanship, and editorial capabilities and administrators in best-practices for the management of research and development (R&D) activities. Working with our network institutions and public health agencies in the LMICs, we will identify and address barriers to downstream application and adoption of research outputs relavant for VBZD control. During the course of this award, we will support advanced training of 8-10 early career scientists for a two-year period in LMIC institutions, and present up to five workshops/webinars annually to broad program participants in different LMIC institutions. We will provide a leadership training opportunity to two advanced researchers at YSPH for 3-months annually to advance research content and mentorship/administration skills.

媒介传播的热带病和被忽视的热带病（分别为 VBD 和 NTD）是地方性流行病， 撒哈拉以南非洲 (sSA) 的新威胁。在这个更新申请中，来自肯尼亚农业的科学家 和畜牧研究组织、生物技术研究所 (BioRI-KALRO) 和耶鲁大学医学院 公共卫生 (YSPH) 将与肯尼亚医学研究所 (KEMRI)、古鲁大学 (GU) 和 媒介和媒介传播疾病研究所 (VVBDI) 及其在肯尼亚、乌干达和坦桑尼亚的同行 东非科学技术委员会 (EASTECO) 支持加强媒介生物学 (VB) 教育和研究能力，以推进病媒控制应用并减少疾病 东非的负担。我们的具体目标是： 目标 1) 为东非的早期职业研究人员提供支持。 我们的培训将针对早期职业科学家，包括博士后学者和初级教师。 我们将传授必要的知识，以提高最先进的实验室和现场研究技能， 数学建模和数据管理 之内 媒介生理学、生态学、人口等广泛领域 遗传学/基因组学和流行病学。我们将在以下地区建立早期职业研究人员的区域网络 中低收入国家机构支持下一代研究人员、现场从业者和政策制定者。我们的 该计划将为学员提供建立独立研究计划所需的技能，并为他们提供建议 国内风险投资和疾病消除计划的可持续和基于证据的战略，以及 促进公众讨论和协商，提高创新和技术的下游交付能力 综合人类、动物和环境健康风险投资技术。 目标 2) 培养传播创新风险投资应用知识的领导力和机构能力。 我们将提供生物伦理学、精通领域的面对面和/或虚拟培训和指导机会 为中低收入国家的早期职业科学家提供临床和实验室实践、媒介管理和生物安全 机构。我们还将对教师进行稿件准备、资助和编辑能力方面的培训 以及管理人员研究和开发 (R&D) 活动管理的最佳实践。 我们将与中低收入国家的网络机构和公共卫生机构合作，确定并解决 下游应用和采用与 VBZD 控制相关的研究成果的障碍。 在此奖项期间，我们将支持 8-10 名早期职业科学家的高级培训 在中低收入国家机构为期两年，每年举办最多五次研讨会/网络研讨会，以开展广泛的计划 不同中低收入国家机构的参与者。我们将为两位高级人士提供领导力培训机会 每年在 YSPH 为研究人员提供为期 3 个月的培训，以推进研究内容和指导/管理技能。