Los Angeles - Southern California (LASC) NIH StrokeNet Regional Coordinating Center

洛杉矶 - 南加州 (LASC) NIH StrokeNet 区域协调中心

基本信息

批准号：
10669559
负责人：
JEFFREY L SAVER
金额：
$ 32.1万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-01 至 2023-12-04
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10669559
关键词：
Academic Medical Centers Acceleration Achievement Acute Address Adherence Adult African American African American population Aging American Award Blood Vessels California Cause of Death Cerebrovascular Disorders Cessation of life Child Clinical Research Clinical Trials Network Collaborations Communities County Dedications Disease Emergency Department Physician Emergency Medicine Ensure Faculty Funding Goals Grant Hispanic Americans Hospitals Impairment Individual Infrastructure Inpatients Intervention Investments Leadership Los Angeles Medical Medical Students Medical center Mentors Minority Groups Multi-Institutional Clinical Trial National Institute of Neurological Disorders and Stroke Neurologist Neurology Neurosurgeon New Mexico Nurses Oranges Outcome Measure Paramedical Personnel Patient Dropouts Patient Noncompliance Patients Pediatric Hospitals Performance Phase Physical Medicine Physical Rehabilitation Physicians Population Premedical Students Prevention Prevention trial Preventive Recovery Rehabilitation Centers Rehabilitation therapy Research Research Personnel Resources Self Perception Stroke Stroke prevention StrokeNet trials System Testing Time Training Translational Research Underserved Population United States United States National Institutes of Health Universities Validation Woman acute stroke arm biomarker validation career cerebrovascular decision-making capacity disability educational atmosphere experience follow-up mid-career faculty neurosurgery neurovascular novel outreach performance site post stroke programs randomized, clinical trials recruit rehabilitative care safety net stroke recovery stroke rehabilitation stroke therapy stroke trials success treatment trial validation studies working group

项目摘要

Stroke is the 2nd leading cause of death and a leading cause of disability in Southern California. It is imperative that new treatments for stroke prevention, acute therapy, and recovery be efficiently developed. This application is to renew the NIH Los Angeles – Southern California StrokeNet Regional Coordinating Center (LASC StrokeNet RCC) that marshals a network of 37 acute stroke and rehabilitation medical centers in Los Angeles and Orange Counties, and New Mexico, which will perform 5-10 NIH StrokeNet trials in prevention, acute, and recovery, efficiently and excellently. Participating hospitals in the network include 7 academic and 30 mixed academic-community and community medical centers. Twelve LASC StrokeNet Working Groups with expertise in specific neurovascular research domains facilitate trial implementation within the Network and serve as a resource to the RCC leadership and to individual performance sites. The four specific aims of this proposal are to: 1) perform high quality NIH StrokeNet acute and prevention trials throughout Los Angeles and Orange Counties, and New Mexico; 2) perform high quality NIH StrokeNet recovery and rehabilitaiton trials throughout Los Angeles and Orange Counties, and New Mexico; 3) ensure participation of high volumes of underserved populations in NIH StrokeNet trials, including women, Hispanic-American, African-American, and other minority populations; and 4) educate fellows, residents, medical students, premedical students, and junior faculty to engage in stroke translational research.

中风是南加州第二大死亡原因，也是导致残疾的主要原因。有效开发中风预防、急性治疗和康复的新疗法势在必行。本申请旨在更新 NIH 洛杉矶 – 南加州 StrokeNet 区域协调中心 (LASC StrokeNet RCC)，该中心汇集了 37 个急性中风和康复医疗中心的网络洛杉矶县、奥兰治县以及新墨西哥州将在 2019 年进行 5-10 次 NIH StrokeNet 试验网络中的参与医院包括 7 家，在预防、急性和康复方面都表现出色。学术中心和 30 个混合学术社区和社区医疗中心，12 个 LASC StrokeNet。具有特定神经血管研究领域专业知识的工作组促进试验的实施网络并作为 RCC 领导层和各个表演场所的资源。该提案的四个具体目标是：1）执行高质量的 NIH StrokeNet 急性和整个洛杉矶县、奥兰治县以及新墨西哥州的预防试验 2) 进行高质量的 NIH；在洛杉矶、奥兰治县和新墨西哥州进行的 StrokeNet 恢复和康复试验 3) 确保大量服务不足的人群（包括女性）参与 NIH StrokeNet 试验，西班牙裔美国人、非裔美国人和其他少数族裔；4) 教育研究员、居民；医学生、医学预科生和初级教师从事中风转化研究。