Forsyth Training in Oral Health Research

福赛斯口腔健康研究培训

基本信息

批准号：
10656564
负责人：
THOMAS Elliott VAN DYKE
金额：
$ 6.98万
依托单位：
ADA FORSYTH INSTITUTE, INC.
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-07-01 至 2027-06-30
项目状态：
未结题

项目摘要

Contact PD/PI: Van Dyke, Thomas In this competing renewal of the Postdoctoral Training Program at the Forsyth, we are excited to propose the expansion of our program to include the DMD/PhD program at our long-time affiliate, Harvard School of Dental Medicine (HSDM). The underlying rationale is to build on the strengths of our current separate training programs that focus on the development of research-focus dentist scientists and oral health researchers and to broaden the scope to include both predoctoral and postdoctoral applicants for academic careers in the NIH funding environment. This application seeks to integrate valuable and synergistic features to enhance the pipeline of dentist scientists and oral health researchers. We will build on the strength of our NIH-sponsored T90/R90 postdoctoral training program to develop a diverse group of committed, highly trained and competitive investigators who seek to obtain collaborative, multidisciplinary research training (basic, translational, or clinical) applicable to oral and craniofacial diseases, conditions and disorders that will take advantage of the most current scientific and collaborative strategies. Collaborative and multidisciplinary research is emphasized, in part, by recruiting trainees into collaborative investigations within or between broadly focused researchers at Forsyth and HSDM. The program is guided by an Internal Advisory Committee (IAC), led by Dr. Thomas Van Dyke (Program Director), Dr. Yingzi Yang (Co-Director) and Dr. Xuesong He (Assistant Director). Expert biannual program review is provided by an External Advisory Committee of Drs. Jane Weintraub (University of North Carolina), Jeffrey Ebersole (University of Nevada, Las Vegas) and Charles Serhan (Harvard Medical School). The program provides support for six trainees per year; 4 postdoctoral and 2 DMD/PhD. Trainees will take required courses/workshops including Responsible Conduct of Research, Methods for Enhancing Reproducibility, Elements of Grant Writing, Grant Review and Support, Maximizing the Mentor-Mentee Relationship, and Effectively Communicating Research. Additional elective and non-elective opportunities will be tailored to the individual's needs and programs. Tutorials and seminars in grantsmanship, grant writing skills, and successful teaching and presentation are each part of trainees’ programs. There are also opportunities for mentoring high school student summer research which not only provides trainees with valuable mentoring experience, but also enriches the pipeline for those selecting research-intensive health-related careers in the future. Trainees’ progress is reviewed weekly by the mentor and semiannually by program staff for reappointment and guidance. An IAC member is assigned to each trainee for guidance and assistance in grant preparation/review. All postdoctoral trainees are required to prepare and submit a K or R grant application and DMD/PhD’s are encouraged to submit F31 applications. Provision is made for informal and formal trainee feedback (current and post-program) and for trainee tracking following completion of the program. Project Summary/Abstract Page 6 Contact PD/PI: Van Dyke, Thomas

联系人 PD/PI：Van Dyke、Thomas 在福赛思博士后培训计划的竞争更新中，我们很高兴地提出扩展我们的项目，将我们的长期附属机构哈佛大学牙科学院的 DMD/PhD 项目纳入其中医学（HSDM）的基本原理是建立在我们当前单独培训计划的优势之上。重点关注以研究为重点的牙医科学家和口腔健康研究人员的发展，并扩大 NIH 资助范围包括博士前和博士后学术职业申请者该应用程序旨在集成有价值的协同功能，以增强管道。我们将利用 NIH 资助的 T90/R90 的实力来发展牙科医生科学家和口腔健康研究人员。博士后培训计划旨在培养一支多元化、忠诚、训练有素且具有竞争力的团队寻求获得协作、多学科研究培训（基础、转化或临床）的研究人员适用于口腔和颅面疾病、病症和失调，将利用最新的技术科学和协作策略在一定程度上得到了强调。招募受训人员参与福赛思和福赛思等广泛关注的研究人员内部或之间的合作调查该计划由 Thomas Van Dyke 博士领导的内部咨询委员会 (IAC) 指导（计划）主任）、杨英子博士（联合主任）和何雪松博士（助理主任）专家项目每两年一次。审查由 Jane Weintraub 博士（北卡罗来纳大学）的外部咨询委员会提供， Jeffrey Ebersole（内华达大学拉斯维加斯分校）和 Charles Serhan（哈佛医学院）。每年为 6 名实习生提供支持；4 名博士后和 2 名 DMD/PhD 实习生将接受所需课程。课程/研讨会包括负责任的研究行为、增强再现性的方法、资助金写作、资助金审查和支持、最大化导师与受训者关系的要素，以及有效交流研究将根据需要量身定制额外的选修和非选修机会。个人的需求和计划，有关补助金、补助金写作技巧和成功的教程和研讨会。教学和演示是学员计划的一部分，还有指导高年级学生的机会。在校学生暑期研究不仅为学员提供了宝贵的指导经验，还丰富了那些未来选择研究密集型健康相关职业的人才的渠道。导师每周审查进展情况，项目工作人员每半年审查进展情况，以便重新任命和指导。为每位学员分配一名 IAC 成员，以在赠款准备/审查方面提供指导和帮助。博士后学员需要准备并提交 K 或 R 资助申请，并且 DMD/PhD 是鼓励提交 F31 申请，提供非正式和正式的实习生反馈（当前和）。项目后）以及项目完成后的学员跟踪。项目总结/摘要第 6 页联系人 PD/PI：Van Dyke、Thomas

项目成果

期刊论文数量（6）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

RvE1 Promotes Axin2+ Cell Regeneration and Reduces Bacterial Invasion.

RvE1 促进 Axin2 细胞再生并减少细菌侵袭。

DOI：
发表时间：
2023-12
期刊：
影响因子：
7.6
作者：
Wu, Y;Yu, N;Rivas, C A;Mehrnia, N;Kantarci, A;Van Dyke, T E
通讯作者：
Van Dyke, T E

Regulatory T cell phenotype and anti-osteoclastogenic function in experimental periodontitis.

实验性牙周炎中的调节性 T 细胞表型和抗破骨细胞生成功能。

DOI：
发表时间：
2020-11-04
期刊：
影响因子：
4.6
作者：
Alvarez, Carla;Suliman, Salwa;Almarhoumi, Rawan;Vega, Maria Elena;Rojas, Carolina;Monasterio, Gustavo;Galindo, Mario;Vernal, Rolando;Kantarci, Alpdogan
通讯作者：
Kantarci, Alpdogan

Proteomic Analyses Discern the Developmental Inclusion of Albumin in Pig Enamel: A New Model for Human Enamel Hypomineralization.

蛋白质组学分析识别猪牙釉质中白蛋白的发育内含物：人类牙釉质低矿化的新模型。

DOI：
发表时间：
2023-10-25
期刊：
影响因子：
5.6
作者：
Gil;Karaaslan, Hakan;Depalle, Baptiste;Sulyanto, Rosalyn;Bidlack, Felicitas B
通讯作者：
Bidlack, Felicitas B

Parkinson's disease is positively associated with periodontal inflammation.

帕金森病与牙周炎症呈正相关。

DOI：
10.1002/jper.23-0274
发表时间：
2023-07-11
期刊：
Journal of periodontology
影响因子：
4.3
作者：
Melis Yilmaz;E. Yay;N. Balci;H. Toygar;B. Kiliç;A. Zirh;Carla Alvarez Rivas;A. Kantarcı
通讯作者：
A. Kantarcı

Enamel multidien biological timing and body size variability among individuals of Chinese Han and Tibetan origins.

中国汉族和藏族个体的牙釉质多日生物时间和体型变异。

DOI：
发表时间：
2020-07-13
期刊：
影响因子：
1.7
作者：
Karaaslan, Hakan;Seckinger, Jeffrey;Almabrok, Amel;Hu, Bin;Dong, Hui;Xia, Dengsheng;Dekyi, Tsering;Hogg, Russell T;Zhou, Jian;Bromage, Timothy G
通讯作者：
Bromage, Timothy G