2009 Glial Biology: Functional Interactions Among Glia & Neurons Gordon Research

2009 神经胶质生物学：神经胶质细胞之间的功能相互作用

• 批准号: 7590634
• 负责人: BRUCE Robert RANSOM
• 金额: $ 2.8万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7590634
• 关键词: Address; Area; Astrocytes; Biology; Brain; California; Cells; Cerebrovascular Circulation; Development; Disease; Energy Metabolism; Goals; Health; Hypoglycemia; International; Microglia; Neuroglia; Neurons; Oligodendroglia; Pain; Participant; Perception; Request for Proposals; Research; Resolution; Series; Societies; Stroke; Structure; Synapses; burden of illness; meetings; nervous system disorder; neurogenesis; posters; programs; public health relevance; symposium; tumor

DESCRIPTION (provided by applicant): This proposal requests partial support for an international meeting on Glial Biology, as part of the Gordon Research Conference series, to be held in Ventura, California, March 15-20, 2009. The broad and long-term goal of the conference is to increase our understanding of the manner in which glial cells interact with one another and with neurons during normal brain function and in neurological diseases. The biology of astrocytes and microglial cells, more than that of oligodendrocytes, is emphasized in this meeting. The specific aim of this meeting will be to convene 44 speakers to discuss critical areas of glial research with a total of 140 participants, during a five-day conference in a relatively isolated setting. The program will have nine sessions that broadly address glia cell involvement in synaptic structure and function, neurogenesis, brain energy metabolism, cerebral blood flow, and some neurological diseases including tumors and stroke. In addition, two poster sessions will permit all participants to contribute to discussion of these topics. The significance of this application is that the Gordon Research Conference on Glial Biology is a essential component of the recurring conferences that promote worldwide research on glial cells, and help define critical research areas in need of experimental resolution. The health relatedness of this application is that glial cells participate in many, possibly all, neurological diseases. Discussions about current research will advance our understanding of glial cells in both health and disease. In addition, specific presentations at this conference will focus on the involvement of glial cells in brain development, tumor formation and spread, normal and deranged energy metabolism (e.g., stroke and hypoglycemia) and pain perception. PUBLIC HEALTH RELEVANCE: The health relatedness of this application is that glial cells participate in many, possibly all, neurological diseases. Discussions about current research will advance our understanding of glial cells in both health and disease. In addition, specific presentations at this conference will focus on the involvement of glial cells in brain development, tumor formation and spread, normal and deranged energy metabolism (e.g., stroke and hypoglycemia) and pain perception. By helping to define key questions that require experimental resolution we can advance our understanding of how glial cells are involved in neurological diseases, which are the first necessary steps to lessening the burden of these diseases on society.

描述（由申请人提供）：本提案请求对神经胶质生物学国际会议提供部分支持，该会议是戈登研究会议系列的一部分，将于 2009 年 3 月 15 日至 20 日在加利福尼亚州文图拉举行。会议的目标是增进我们对正常大脑功能和神经系统疾病期间神经胶质细胞彼此相互作用以及与神经元相互作用的方式的了解。这次会议强调了星形胶质细胞和小胶质细胞的生物学特性，而不是少突胶质细胞的生物学特性。本次会议的具体目标是在相对孤立的环境中召开为期五天的会议，召集 44 名发言者，与总共 140 名与会者讨论神经胶质研究的关键领域。该计划将有九场会议，广泛讨论神经胶质细胞参与突触结构和功能、神经发生、脑能量代谢、脑血流以及包括肿瘤和中风在内的一些神经系统疾病。此外，两次海报会议将允许所有参与者为这些主题的讨论做出贡献。这一应用的意义在于，戈登神经胶质生物学研究会议是定期会议的重要组成部分，这些会议促进了全球神经胶质细胞研究，并帮助确定需要实验解决的关键研究领域。该应用的健康相关性在于神经胶质细胞参与许多（可能是所有）神经系统疾病。对当前研究的讨论将增进我们对健康和疾病中神经胶质细胞的理解。此外，本次会议的具体演讲将重点关注神经胶质细胞在大脑发育、肿瘤形成和扩散、正常和紊乱的能量代谢（例如中风和低血糖）和疼痛感知中的参与。公共健康相关性：本申请的健康相关性在于神经胶质细胞参与许多（可能是所有）神经系统疾病。对当前研究的讨论将增进我们对健康和疾病中神经胶质细胞的理解。此外，本次会议的具体演讲将重点关注神经胶质细胞在大脑发育、肿瘤形成和扩散、正常和紊乱的能量代谢（例如中风和低血糖）和疼痛感知中的参与。通过帮助定义需要实验解决的关键问题，我们可以加深对神经胶质细胞如何参与神经系统疾病的理解，这是减轻这些疾病给社会造成的负担的首要必要步骤。