International Pediatric Nephrology Association (IPNA) Eighth Symposium on Growth

国际儿科肾脏病协会（IPNA）第八届生长研讨会

• 批准号: 7675762
• 负责人: Frederick Kaskel
• 金额: $ 1.8万
• 依托单位: MONTEFIORE MEDICAL CENTER (BRONX, NY)
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7675762
• 关键词: Address; Adolescent; Adult; American; Cessation of life; Child; Childhood; Chronic Kidney Failure; Clinical; Clinical Investigator; Cohort Studies; Data; Databases; Defect; Development; Disease; Endocrinologist; Etiology; Failure; Feedback; Genetic; Goals; Grant; Growth; Growth Disorders; Health; Height; Hospitalization; Impairment; Incidence; Infant Care; Information Systems; International; Kidney; Mind; Molecular; Morbidity - disease rate; Nephrology; Patients; Peer Review; Prevalence; Regulation; Research; Research Personnel; Risk; Role; Spain; Stimulus; Travel; United States; Update; cardiovascular risk factor; collaborative trial; innovation; interest; meetings; mortality; nutrition; posters; prevent; success; symposium; web site

DESCRIPTION (provided by applicant): The International Pediatric Nephrology Association's (IPNA) Eighth Symposium on Growth and Nutrition in Children with Chronic Renal Disease will address the major challenges facing pediatric nephrologists and endocrinologists in the care of infants, children and adolescents with disorders of growth who are at risk for significant co-morbidities and mortality. The symposium will build upon the success of the prior conferences to provide: 1) in depth-discussion and updates on outstanding hot topics, 2) information on ongoing and innovative lines of research, 3) the proper framework for interaction between clinical and basic investigators, and 4) a stimulus for the incorporation of new groups of research and young investigators. Growth retardation is a common result of CKD in childhood and results in failure of the patient to achieve the final adult height consistent with their genetic potential. Despite major advances in our understanding of the cellular and molecular etiologies for the growth abnormalities, as well as, well-defined therapies aimed at preventing or correcting the growth defects, 37% of children with CKD in the North American Pediatric Renal Trials and Collaborative Studies database had statutory growth impairment. Additionally, data from the United States Renal Data System database has demonstrated that patients with severe-to-moderate growth failure had increased hospitalizations rates and increased risk of death. The role of growth impairment in the higher incidence and prevalence of pediatric-onset cardiovascular risk factors in CKD remains to be characterized. With these issues in mind, and the results of the current NIDDK-support Chronic Kidney Disease in Children Cohort Study, an international scientific organizing committee under the guidance of the IPNA, has assembled a distinguished group of investigators with expertise in growth and its regulation in health and disease, in order to convene a three day interactive scientific meeting in Olviedo, Spain, aimed at stimulating new research in the field and facilitating the development of new investigators and trainees. Competitive travel grants will provide the opportunity for their attendance and participation in the meeting with peer-reviewed poster sessions of their research for critical feedback from senior investigators. A website will disseminate meeting information.

描述（由申请人提供）：国际小儿肾脏学协会（IPNA）关于慢性肾脏疾病儿童成长和营养的第八次研讨会将解决针对婴儿，儿童和青少年患者，患有对重要企业的疾病的儿童和青少年的小儿肾病学家和内分泌学家面临的主要挑战，对有巨大的co co-morborbidities和Morterbicities风险有危险。研讨会将基于先前会议提供的成功：1）深度讨论和出色的热门话题的最新信息，2）有关正在进行的和创新的研究线的信息，3）临床和基本研究人员之间的相互作用的正确框架，以及4）刺激了新的研究和年轻研究人员的刺激。生长迟钝是CKD童年时期的常见结果，导致患者无法达到与其遗传潜力一致的最终成人身高。尽管我们对生长异常的细胞和分子病因的理解取得了重大进展，以及旨在预防或纠正生长缺陷的定义明确的疗法，但在北美儿科肾脏肾脏肾脏试验和协作数据库数据库中，有37％的CKD儿童有法规障碍。此外，美国肾脏数据系统数据库的数据表明，严重到中度生长失败的患者的住院率增加并增加了死亡风险。生长障碍在CKD中儿科发作的心血管危险因素的发病率和流行率中的作用尚待表征。考虑到这些问题，以及在iPNA指导下的国际科学组织委员会中，当前NIDDK-Support慢性肾脏疾病的结果，在iPNA的指导下，召集了一群杰出的研究人员，具有在健康和疾病方面的成长及其调节方面的专业知识，以使其在Spain and Spain Interviedo and Interive and Spen Interviede Inter Inding and Inting Inding In in Aim in the News Internigation int in of Newhd Acnitive In the New the Spection Inding In攻击。学员。竞争性的旅行赠款将为他们的出席和参加会议提供机会，并通过同行评审的海报会议会议，以获取高级研究人员的关键反馈。网站将传播会议信息。