Conference Grant Proposal: 12th Congress of the International Photodynamic Assn

会议拨款提案：国际光动力协会第十二届大会

• 批准号: 7674450
• 负责人: David Harry Kessel
• 金额: $ 0.5万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7674450
• 关键词: Applications Grants; Area; Cancer Detection; Clinical Sciences; Congresses; Diagnosis; Diagnostic; Disease; Fluorescent Dyes; Funding; International; Laboratory Scientists; Light; Malignant Neoplasms; Modality; Monitor; Optics; Photochemistry; Photochemotherapy; Photosensitizing Agents; Physicians; Poison; Postdoctoral Fellow; Procedures; Public Health; Research Personnel; Scientist; Site; Students; Therapeutic; Time; Visible Radiation; authority; base; cancer therapy; cell injury; cost; design; improved; interest; irradiation; public health relevance; symposium; tumor

DESCRIPTION (provided by applicant): Photodynamic Therapy (PDT) is a photochemistry based approach to the treatment of disease and relies on the use of light to activate certain non-toxic chemicals called photosensitizers. An attribute of PDT is its dual selectivity conferred by the localization of the photosensitizers and the spatial confinement of light. PDT is approved by regulatory authorities world-wide for a number of cancer and non-cancer applications and continues to emerge as a potential therapeutic modality for a variety of new indications. Because of the ability of most of the PDT agents to fluoresce, advances in optical diagnostic and therapy monitoring modalities have also evolved rapidly and online monitoring and therapy approaches are being developed. The 13th Congress of the International Photodynamic Association Conference will be held in Seattle (11- 15 June 2009) and is expected to attract physicians and scientists from the world over and is aimed at being forward-looking, projecting areas most amenable to Photodynamic Therapy as well as capturing the current status of the field. Both basis science and clinical topics will be covered allowing adequate times for discussion. The conference should be useful to those already in the field of PDT and also to those contemplating entering it. This is anticipated to be a particularly good forum for exchange of ideas between laboratory scientists and clinicians. Of particular interest to the association is the attendance by students and postdoctoral fellows and effort is being made to provide funding for these young scientists to defray some of the conference costs. Public Health Relevance: This conference is designed to improve public health by providing a format for investigators to exchange information in an emerging procedure for cancer detection and treatment. The use of fluorescent agents that localize at tumor sites facilitates diagnosis. The ability of these agents to cause a highly-selective form of cell damage upon irradiation with visible light can be utilized in cancer treatment procedures.

描述（由申请人提供）：光动力疗法（PDT）是一种基于光化学的疾病治疗方法，依赖于使用光来激活某些称为光敏剂的无毒化学物质。 PDT 的一个属性是其由光敏剂的定位和光的空间限制赋予的双重选择性。 PDT 已获得世界各地监管机构的批准，可用于多种癌症和非癌症应用，并不断成为各种新适应症的潜在治疗方式。由于大多数 PDT 药物能够发出荧光，光学诊断和治疗监测方式的进步也迅速发展，并且正在开发在线监测和治疗方法。国际光动力协会第十三届大会将于 2009 年 6 月 11 日至 15 日在西雅图举行，预计将吸引来自世界各地的医生和科学家，会议旨在具有前瞻性，将最适合光动力疗法的领域预测为以及捕捉该领域的当前状态。将涵盖基础科学和临床主题，以便有足够的时间进行讨论。这次会议对于那些已经进入 PDT 领域的人以及那些考虑进入该领域的人来说应该是有用的。预计这将成为实验室科学家和临床医生之间交流思想的一个特别好的论坛。该协会特别感兴趣的是学生和博士后研究员的出席，并且正在努力为这些年轻科学家提供资金，以支付部分会议费用。 公共健康相关性：本次会议旨在通过为研究人员提供一种在新兴的癌症检测和治疗程序中交换信息的形式来改善公共健康。使用定位于肿瘤部位的荧光剂有助于诊断。这些试剂在可见光照射下引起高度选择性形式的细胞损伤的能力可用于癌症治疗过程。