238th American Chemical Society National Meeting

第 238 届美国化学会全国会议

• 批准号: 7749286
• 负责人: SHANA J STURLA
• 金额: $ 1万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7749286
• 关键词: American; Analytical Chemistry; Applications Grants; Area; Award; Biological; Chemicals; Chemistry; Communities; Complex; DNA Adducts; Development; Disease; District of Columbia; Ensure; Environmental Health; Etiology; Funding; Goals; Health; Human; Individual; Link; Malignant Neoplasms; Mass Spectrum Analysis; Medicine; Monitor; Organic Chemistry; Pharmaceutical Preparations; Platinum; Postdoctoral Fellow; Request for Applications; Research; Risk; Risk Assessment; Scientist; Series; Societies; Solutions; System; Therapeutic; Toxic effect; Toxicology; Travel; United States National Institutes of Health; Work; base; cancer therapy; chemical carcinogenesis; drug discovery; drug metabolism; graduate student; human disease; improved; innovation; meetings; mitochondrial dysfunction; next generation; novel strategies; programs; public health relevance; safety testing; symposium

DESCRIPTION (provided by applicant): This grant application requests funding for partial support of a series of symposia with the title "New Facets of Chemical Toxicology." These symposia are part of the program to be presented by the American Chemical Society Division of Chemical Toxicology at the 238th National Meeting and Exposition of the Society in Washington, DC on August 16-20, 2009. These symposia will provide forums for the presentation of new research that emphasizes modern scientific approaches and applications based in chemical toxicology, including (1) Advances in Aquatic Toxicology, with emphasis on linking mechanism and monitoring to improve risk assessment, (2) Human Drug Metabolites in Safety Testing, (3) Drug-Induced Mitochondrial Dysfunction and Human Disease, (4) DNA Adducts and Human Health, and (5) New approaches for Cancer Therapy involving Platinum-based Chemotherapeutics. Chemistry research in the area of toxicology has recently shifted to the development of newer strategies for better understanding mechanistic aspects of interactions of chemicals with complex biological and environmental systems. Progress in applying this understanding to human health concerns has great potential for innovative and dramatic advances. However, a continued challenge imposed by the breadth of the field centers on bringing together individuals who are all focused on chemistry-based solutions, but immersed within diverse biomedical arenas. Thus, this meeting is needed as a premiere national venue to bring this diverse group of chemists together, and a highly respected and diverse group of scientists have agreed to present their newest findings. Public Health Relevance: The planned symposia have relevance to the goals of the National Institutes of Health in the areas of environmental health, cancer therapeutics and etiology, drug metabolism and toxicity, and general medicine. The broader scientific community will also find the information presented relevant in the fields of biological, medicinal and analytical chemistry as well as chemical toxicology. Travel awards will be made to graduate students and postdoctoral fellows to ensure that the next generation of scientists is aware of the important advances in the fields of drug discovery, mass spectrometry, synthetic organic chemistry and chemical carcinogenesis to mention a few and how they work in concert to develop new ways to determine disease etiology and risk.

描述（由申请人提供）：本拨款申请要求为题为“化学毒理学的新方面”的一系列研讨会提供部分支持。这些研讨会是美国化学会化学毒理学部将于 2009 年 8 月 16 日至 20 日在华盛顿特区举行的第 238 届学会全国会议和博览会上提出的计划的一部分。这些研讨会将为介绍以下内容提供论坛：强调基于化学毒理学的现代科学方法和应用的新研究，包括（1）水生毒理学进展，重点是将机制和监测联系起来以改进风险评估， (2) 安全测试中的人类药物代谢物，(3) 药物引起的线粒体功能障碍和人类疾病，(4) DNA 加合物和人类健康，以及 (5) 涉及铂类化疗的癌症治疗新方法。毒理学领域的化学研究最近转向开发新策略，以更好地理解化学品与复杂生物和环境系统相互作用的机制。将这种理解应用于人类健康问题的进展具有巨大的创新和巨大进步潜力。然而，该领域的广度所带来的持续挑战集中在将专注于基于化学的解决方案但沉浸在不同生物医学领域的个人聚集在一起。因此，这次会议需要作为一个全国性的重要场所，将这些不同的化学家聚集在一起，并且一群备受尊敬的多元化科学家已同意展示他们的最新发现。 公共卫生相关性：计划召开的研讨会与美国国立卫生研究院在环境健康、癌症治疗和病因学、药物代谢和毒性以及普通医学领域的目标相关。更广泛的科学界还将发现所提供的与生物、医学和分析化学以及化学毒理学领域相关的信息。将为研究生和博士后研究员提供旅行奖励，以确保下一代科学家了解药物发现、质谱、合成有机化学和化学致癌等领域的重要进展以及它们如何在这些领域发挥作用。共同开发确定疾病病因和风险的新方法。