International Gap Junction Conference 2009

2009年国际间隙连接会议

• 批准号: 7750265
• 负责人: Scott Boitano
• 金额: $ 1.73万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7750265
• 关键词: Arizona; Biological Process; Cell Communication; Cells; Collaborations; Communication; Connexins; Development; Disabled Persons; Family; Fostering; Funding; Gap Junctions; Goals; Heart; Human body; Individual; International; Ion Channel; Learning; Link; Minority; Movement; Mutation; Myocardial; Proteins; Request for Applications; Research Personnel; Series; Structure; Techniques; Woman; abstracting; human disease; meetings; member; small molecule; symposium

DESCRIPTION (provided by applicant): Virtually all cells in the human body form gap junctions. These structures are membrane channels that connect apposing cells and provide for the direct movement of small molecules between cells. This form of cell communication is critical in a wide variety of biological processes, e.g., in synchronizing the beating of myocardial cells within the heart. We have recently learned that more than 20 human diseases are linked to mutations in the channel proteins found in gap junctions, members of the "connexin" family. With the rapid developments in the field, investigators have found recurring scientific meetings to be especially valuable forums for the exchange of ideas and techniques that pave the way for scientific discovery. This application requests funds for the 2009 International Gap Junction Conference, to be held in Sedona, Arizona July 25-30. This meeting represents the 12th in a unique series of biennial interdisciplinary meetings focused on gap junctions and the communication mechanisms associated with them. The overall goals of this meeting are to achieve a better understanding of connexins and gap junctions in both normal and diseased states, as well as to provide a continuing forum for the fostering productive collaborations and attracting young investigators, particularly, women, minorities and disabled individuals, to the field. (End of Abstract)

描述（由申请人提供）： 实际上，人体中的所有细胞构成了间隙连接。这些结构是连接细胞的膜通道，并提供了细胞之间小分子的直接运动。这种细胞通信形式在各种生物学过程中至关重要，例如，在同步心脏内的心肌细胞的殴打时。我们最近了解到，“连接蛋白”家族的成员在Gap连接处发现的通道蛋白中，有20多种人类疾病与突变有关。随着该领域的快速发展，调查人员发现，经常出现的科学会议是交换思想和技术的特别有价值的论坛，为科学发现铺平了道路。该申请要求于7月25日至30日在亚利桑那州塞多纳举行的2009年国际差距会议上要求资金。这次会议代表了一系列两年一次的跨学科会议中的第十二次会议，该会议的重点是间隙连接及其相关的沟通机制。这次会议的总体目标是更好地了解常规和患病国家的连接蛋白和差距连接，并为促进生产性合作的持续论坛提供一个持续的论坛，并吸引年轻的调查人员，尤其是妇女，少数民族和残疾人。 （抽象的结尾）