Training Program in Translational Research

转化研究培训计划

• 批准号: 10618868
• 负责人: ANDREW P LIEBERMAN
• 金额: $ 31.83万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10618868
• 关键词: Training Programs; Translational Research

Abstract The Training Program in Translational Research offers an interdisciplinary program of study and research that prepares graduate students for successful careers at the interface between basic biomedical science and clinical medicine. This program is designed for predoctoral Ph.D. students and aims to address the widely-recognized shortage of rigorously trained scientists who can successfully work together with medical professionals to bridge the gap between basic science and clinical practice. Annual support for 6 trainees (3 in their 2nd year and 3 in 3rd year of graduate studies) is requested throughout five years of funding. The program is centered in the University of Michigan School of Medicine, with participating faculty members affiliated with ten departments (6 clinical and 4 basic science) providing multidisciplinary training for graduate students in 15 degree-granting programs. Additional faculty mentors have their primary appointments in the College of Pharmacy, the School of Dentistry and the College of LSA. These faculty members were selected because of their commitment to graduate education and expertise in translational research. Based on the long-standing research interests of these preceptors, scientific projects will be focused on areas of excellence in cancer biology, epigenetics, aging, immunology, neuroscience, omics studies, precision medicine and experimental therapeutics & biomarkers. This broad spectrum of research activities provides a wide-range of exciting opportunities for students to work on translational research projects. The educational experience will be enhanced and supported by integration of dual-mentors with corresponding expertise in the basic and clinical aspects of the research project. The curriculum includes innovative, individualized and competency-based coursework in translational science, training in the performance of rigorous and reproducible research, and participation in clinical rotations, interdisciplinary conferences, tumor boards, and grand rounds. These activities will be complemented by a T32- based seminar series, workshops, annual retreat, and career development support. Our goal is to foster the training of basic researchers who will interact with clinicians and laboratory professionals to become future leaders in translating research findings into clinical practice to improve patient outcomes. The program will be administered by co-directors who are experienced in, and passionate about, graduate student education and translational research. The program will benefit from the advice and oversight of internal and external advisory committees, both of which will assist the co-directors in running and evaluating the program. Graduates from this program will have the skills and knowledge to undertake independent careers that feature translational and multidisciplinary research. In summary, the strengths of this training program are the direct link between the basic and clinical sciences, the collegial and successful preceptors, the experienced program leadership, and the rich academic research and clinical environment at the University of Michigan.

抽象的 翻译研究的培训计划提供了一个跨学科的研究计划 在基本生物医学科学与临床之间的界面上为成功的职业准备研究生 药品。该程序是为博士学位博士设计的。学生并旨在解决广泛认可的 缺乏受过严格培训的科学家，他们可以成功与医疗专业人员一起桥接 基础科学与临床实践之间的差距。对6名学员的年度支持（第二年为3名，第三年为3 整个五年的资金都要求研究生学年。该计划以大学为中心 密歇根州医学院的教职员工隶属于十个部门（6个临床和 4基础科学）为研究生提供15个学位课程的研究生培训。 其他教师导师在药学学院，牙科学院有主要任命 和LSA学院。这些教职员工之所以被选中，是因为他们致力于毕业 翻译研究的教育和专业知识。基于这些长期的研究兴趣 主教，科学项目将集中在癌症生物学，表观遗传学，衰老， 免疫学，神经科学，OMICS研究，精密医学和实验治疗和生物标志物。这 广泛的研究活动为学生提供了许多令人兴奋的机会 翻译研究项目。通过整合的教育经验将得到增强和支持 在研究项目的基本和临床方面具有相应专业知识的双重训练器。这 课程包括转化科学的创新，个性化和基于能力的课程， 培训严格和可重复的研究以及参与临床旋转的培训， 跨学科会议，肿瘤委员会和大回合。这些活动将由T32-补充 基于研讨会系列，研讨会，年度务虚会和职业发展支持。我们的目标是促进 培训将与临床医生和实验室专业人员互动的基础研究人员，以成为未来 将研究结果转化为临床实践以改善患者预后的领导者。该程序将是 由经验丰富和热情的研究生教育和热情的联合主席管理 翻译研究。该计划将受益于内部和外部咨询的建议和监督 委员会都将协助联合导演运行和评估该计划。毕业生 计划将拥有技能和知识来从事具有翻译和的独立职业 多学科研究。总而言之，该培训计划的优势是 基础和临床科学，合作和成功的主持人，经验丰富的计划领导力以及 密歇根大学的丰富学术研究和临床环境。