International Research in Thailand

泰国的国际研究

• 批准号: 7732717
• 负责人: Steven Holland
• 金额: $ 5.52万
• 依托单位: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7732717
• 关键词: Anonymous Testing; Asians; Autoantibodies; Blood Banks; Disease; Enrollment; Goals; Histoplasmosis; Interferon Type II; International; Laboratories; Lymphocyte Count; Mycobacterium Infections; Opportunistic Infections; Patients; Plasma; Population; Protocols documentation; Reporting; Research; Research Ethics Committees; Research Infrastructure; Sampling; Series; Thailand; United States; United States National Institutes of Health; cytokine

We have previously shown that autoantibodies to interferon gamma exist in patients in this population in northern Thailand, and that blood bank donors do not have these autoantibodies. We have spend the last year developing the protocol and infrastructure in Thailand to execute this project, which is now ready to enroll as soon as the final IRB approvals are received. We have developed the local laboratory support to obtain appropriate lymphocyte counts and plasma samples and cytokine stimulations for shipment to the NIH for analysis.

我们以前已经表明，泰国北部人群中的患者中存在干扰素伽玛的自身抗体，而血库捐献者没有这些自身抗体。在最后一年，我们已经在泰国开发协议和基础架构来执行该项目，该项目现在准备在收到最终IRB批准后立即注册。我们已经开发了当地的实验室支持，以获得适当的淋巴细胞计数，血浆样品和细胞因子刺激，以将其运送到NIH进行分析。