Digital Technology Core

数字技术核心

基本信息

批准号：
10369042
负责人：
Zachary Beattie
金额：
$ 30.32万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2025-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10369042
关键词：
Aging Agitation Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Analgesics Appointment Area Atrophic Automobile Driving Behavior Biological Markers Caregivers Clinical Clinical Markers Clinical assessments Cognition Collaborations Communities Computers Computing Methodologies Data Dementia Devices Diagnosis Early Diagnosis Elderly Environment Evolution Fostering Gait speed Genetic Home Impaired cognition Intervention Investigation Laboratories Life Liquid substance Maps Measurement Measures Medial Methodology Modeling Monitor Moods Motor Oregon Outcome Participant Pathologic Pathology Patients Pattern Peer Review Pharmaceutical Preparations Phase Physical activity Physiology Process Protocols documentation Psychometrics Research Research Personnel Resources Risk Sampling Sister Sleep Symptoms Technology Temporal Lobe Testing Time Visit advanced dementia aging brain care recipients cognitive change cohort computational platform dementia care digital experience follow-up improved insight interest novel strategies programs sensor social engagement statistics training opportunity video chat volunteer white matter change

项目摘要

Project Summary: Digital Technology Core Given limitations of conventional clinical assessments to precisely map change trajectories, our research community increasingly seeks methodologies that incorporate continuous, real-world and objective measurement of key features (e.g., mobility, cognition, sleep, medication taking, driving) using the pervasive computing platform and methodologies of ORCATECH (Oregon Center for Aging & Technology). This new approach has important application in many areas of dementia research beyond early detection, such as caregiver/care recipient activities; agitation in institutional settings; and objective digital biomarkers (DB) of sleep, physical activity, and the environment. Use of these technologies is not limited to assessment, but may also deliver interventions, such as dementia care programs via home video. Given the growing use and promise of DB and related technologies, this proposal will consolidate and build upon recent advances through the Oregon Alzheimer’s Disease Research Center’s Digital Technology Core (DTC). Specific Aims are: 1. To maintain and make available for research, an OADRC dementia-specific focused Life Laboratory cohort of research volunteers (healthy controls, MCI, and AD) who will have deployed in their homes state-of-the-art sensing and pervasive computing platforms. 2. To obtain and make available for research, DB data on OADRC subjects. 3. To foster collaborative research involving DB and related technologies.

项目概要：数字技术核心鉴于传统临床评估在精确绘制变化轨迹方面的局限性，我们的研究社区越来越多地寻求结合连续的、真实的和客观的方法使用普遍的方法测量关键特征（例如活动能力、认知、睡眠、服药、驾驶） ORCATECH（俄勒冈老龄化与技术中心）的计算平台和方法。除了早期检测之外，该方法在痴呆症研究的许多领域都有重要的应用，例如护理者/护理接受者的活动；以及客观数字生物标志物 (DB) 这些技术的使用不仅限于评估，还可以用于评估。还提供干预措施，例如通过家庭视频进行痴呆症护理计划。 DB 和相关技术的承诺，该提案将通过以下方式巩固和建立在最新进展的基础上：俄勒冈州阿尔茨海默病研究中心的数字技术核心 (DTC) 的具体目标是： 1. 维护并提供 OADRC 专门针对痴呆症的生命实验室进行研究将部署在家中的研究志愿者群体（健康对照组、MCI 和 AD）最先进的传感和普适计算平台。 2. 获取 OADRC 主题的 DB 数据并供研究使用。 3. 促进数据库及相关技术的合作研究。