CELLULAR MECHANISMS OF ALCOHOL INJURY OF GASTRIC MUCOSA

酒精损伤胃粘膜的细胞机制

• 批准号: 2044111
• 负责人: ANDRZEJ S TARNAWSKI
• 金额: $ 16.49万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-07-01 至 1993-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2044111
• 关键词: CELLULAR; MECHANISMS; ALCOHOL; INJURY; GASTRIC

项目成果

Increased susceptibility to injury and normal reactivity to prostaglandin protection of mucous cells isolated from gastric mucosa of portal hypertensive rats.

门静脉高压大鼠胃粘膜分离的粘液细胞对损伤的敏感性增加，对前列腺素保护的反应性正常。

• DOI: 10.1016/0090-6980(93)90076-j
• 发表时间: 1993
• 期刊: Prostaglandins
• 作者: Arakawa,T;Tarnawski,A;Mach,T;Fukuda,T;Stachura,J;Sarfeh,IJ;Kobayashi,K
• 通讯作者: Kobayashi,K

Direct protective action of epidermal growth factor on isolated gastric mucosal surface epithelial cells.

表皮生长因子对离体胃粘膜表面上皮细胞的直接保护作用。

• 发表时间: 1992
• 期刊: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
• 作者: Ishikawa,T;Fukuda,T;Sugiyama,M;Tarnawski,A
• 通讯作者: Tarnawski,A

Adaptation of gastric mucosa to chronic alcohol administration is associated with increased mucosal expression of growth factors and their receptor.

胃粘膜对长期饮酒的适应与生长因子及其受体的粘膜表达增加有关。

• DOI: 10.3109/00365529209096007
• 发表时间: 1992
• 期刊: Scandinavian journal of gastroenterology. Supplement
• 作者: Tarnawski,A;Lu,SY;Stachura,J;Sarfeh,IJ
• 通讯作者: Sarfeh,IJ

Calcium channel blockers and prostaglandin generation by gastric surface epithelial cells.

钙通道阻滞剂和胃表面上皮细胞产生前列腺素。

• DOI: 10.1016/0090-6980(91)90020-g
• 发表时间: 1991
• 期刊: Prostaglandins
• 作者: Fukuda,T;Arakawa,T;Mach,T;Durbin,T;Tarnawski,A
• 通讯作者: Tarnawski,A