Networks underlying visual modulation of speech perception

语音感知视觉调制的网络

基本信息

批准号：
8959922
负责人：
David Brang
金额：
$ 13.74万
依托单位：
NORTHWESTERN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-12-01 至 2016-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8959922
关键词：
Accounting American Aphasia Area Auditory Auditory area Autistic Disorder Brain Chicago Cognitive Cues Development Development Plans Diffusion Magnetic Resonance Imaging Educational workshop Electrocorticogram Electroencephalography Environment Epilepsy Equilibrium Evaluation Face Processing Fusiform gyrus Goals Health Human Image Individual Individual Differences Knowledge Language Leadership Lip structure Lipreading Magnetic Resonance Imaging Measurement Measures Mediating Mentors Modality Modeling Monitor Movement Neurology Noise Operative Surgical Procedures Oral cavity Pathway interactions Patients Positioning Attribute Postdoctoral Fellow Prevalence Process Psychology Psychophysics Research Research Personnel Scalp structure Schizophrenia Scientist Signal Transduction Societies Speech Speech Perception Speed Structure of superior temporal sulcus Techniques Testing Training Universities Visual Visual Motion Weight area MT audiovisual speech base career development clinically relevant cognitive neuroscience experience graduate student healthy aging individual patient language processing meetings memory process multisensory neuroimaging novel programs research and development research study speech processing support network symposium temporal measurement tenure track visual information visual speech

项目摘要

DESCRIPTION (provided by applicant): The proposed research seeks to identify the anatomical and functional networks that support the facilitation of auditory speech processes by visual information. This research line is built on a novel model describing low- and high-level multisensory mechanisms that mediate speech perception processes and is evaluated by anatomical and functional measures of connectivity in typically developing individuals and patients with epilepsy. These aims will be accomplished through a detailed career development plan outlining my training in functional measures of connectivity using electroencephalography (EEG), intracranial electrocorticography (ECoG) in patients with epilepsy, as well as training in rigorous research on speech perception and epilepsy. This training regiment is supported by a team of respected scientists who together have expertise in each aspect of my research and career development plans. Drs. Suzuki and Grabowecky have expertise in auditory- visual multisensory processes including speech perception. Dr. Paller is an esteemed EEG and MRI researcher who has an established record of successfully training graduate students and post-doctoral researchers who advance to tenure-track positions at top Universities. Dr. Leo Towle from the University of Chicago is an established epilepsy researcher and neurophysiologist who uses intracranial ECoG measurements to study memory and language processes. Furthermore, each of these mentors has an excellent track record of administrative and leadership experience: Dr. Grabowecky as former assistant Chair of the Psychology Department, Dr. Paller as the Director of the Cognitive Neuroscience program, Dr. Towle as former Chair of Neurology and President of the American Society of Neurophysiologic Monitoring, and Dr. Suzuki as the Director of the Cognitive Division of the Psychology Department. Training from my mentors will be supplemented by attending four technique-based workshops, four academic conferences each year, as well as weekly meetings with each mentor and scholarly meetings at Northwestern University and the University of Chicago to discuss recent research. The overarching goal for this proposal is to advance my understanding of multisensory and speech related processes in order to conduct leading health-related research and to obtain a tenure-track position at a top research university. Supported by a thorough training regiment, this proposed research will provide a thorough understanding of the mechanisms that support multisensory speech perception and will provide clinically relevant understanding of multisensory processes as a compensatory mechanism.

描述（由申请人提供）：拟议的研究旨在识别支持视觉信息促进听觉言语过程的解剖和功能网络。该研究系列建立在一种新颖的模型之上，该模型描述了介导言语感知过程的低级和高级多感觉机制，并通过典型发育个体和癫痫患者的连接性的解剖学和功能性测量进行评估。这些目标将通过详细的职业发展计划来实现，该计划概述了我对癫痫患者使用脑电图（EEG）、颅内皮层电图（ECoG）进行连接功能测量的培训，以及对言语感知和癫痫的严格研究的培训。这个训练团得到了一群受人尊敬的科学家的支持，他们在我的研究和职业发展计划的各个方面都拥有专业知识。博士。铃木和格拉博威基拥有包括言语感知在内的听觉视觉多感官过程方面的专业知识。 Paller 博士是一位受人尊敬的脑电图和 MRI 研究员，在成功培训研究生和博士后研究人员方面拥有良好的记录，这些学生和博士后研究人员晋升为顶尖大学的终身教授职位。芝加哥大学的 Leo Towle 博士是一位知名的癫痫研究员和神经生理学家，他使用颅内 ECoG 测量来研究记忆和语言过程。此外，这些导师中的每一位都拥有出色的行政和领导经验记录：Grabowecky 博士担任心理学系前助理系主任，Paller 博士担任认知神经科学项目主任，Towle 博士担任神经病学前系主任，美国神经生理监测学会主席，铃木博士担任心理学系认知部主任。我的导师的培训将通过参加四次基于技术的研讨会、每年四次学术会议以及与每位导师的每周会议以及西北大学和芝加哥大学的学术会议来补充，以讨论最近的研究。该提案的总体目标是增进我对多感官和言语相关过程的理解，以便进行领先的健康相关研究并获得顶尖研究型大学的终身教授职位。在彻底的训练团的支持下，这项拟议的研究将提供对支持多感官语音感知的机制的透彻理解，并将提供对作为补偿机制的多感官过程的临床相关理解。