MINOR DEPRESSION--PSYCHOSOCIAL TREATMENT IN PRIMARY CARE

轻度抑郁症——初级保健中的心理社会治疗

• 批准号: 2415793
• 负责人: CHARLOTTE BROWN
• 金额: $ 11.44万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-30 至 2000-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2415793
• 关键词: behavioral /social science research tag; clinical depression; clinical trials; health care cost /financing; human subject; human therapy evaluation; mental disorder diagnosis; nurse practitioners; nursing intervention; primary care physician; problem solving; psychometrics; psychotherapy; therapy compliance

DESCRIPTION (Adapted from the Applicant's Abstract): The program of training and research outlined in this revised application for a Scientist Development Award for Clinicians (SDAC) focuses on developing the candidate's expertise in applying randomized clinical trails methodology to clinical services research in a primary care setting, with Herbert C. Schulberg, Ph.D., Professor of Psychiatry, Psychology, and Medicine, University of Pittsburgh School of Medicine, as Preceptor. The career development plans include training in psychiatric and medical epidemiology, psychometrics, health economics, and biostatistics. Planned tutorials are "Integrating Behavioral Interventions into Primary Health Care" and "Evaluating the Cost-Effectiveness of Psychiatric Treatment in Primary Care." The proposed research evaluates the efficacy of psychosocial treatment and course of recovery in primary care patients with minor depression. There is growing evidence that significant impairment in subjective well- being and functional status, and increased health care utilization are associated with minor depression. Yet, effective and feasible treatment options have received little attention. A randomized, clinical trial conducted at four urban health centers in Pittsburgh, PA is proposed to examine the efficacy of problem-solving therapy (PST) provided by nurse clinicians for primary care patients with minor depression. The outcomes of PST provided by nurse clinicians will be compared to the outcomes experienced by patients receiving usual care from their primary care physician. The integrity of the treatment provided by nurses will be evaluated with a scale to be developed by the candidate during the start-up phase of the study. The efficacy of PST will be assessed through multiple domains, including both symptomatic and functional changes following treatment. It is hypothesized that patients receiving PST will show greater symptomatic and functional improvement than those receiving usual care. Additionally, a pilot study of the cost- effectiveness of PST in primary care patients with minor depression will be undertaken during the award period.

描述（根据申请人的摘要改编）： 此修订的申请中概述的培训和研究 科学家临床医生发展奖（SDAC）专注于发展 候选人在应用随机临床踪迹方面的专业知识 初级保健环境中临床服务研究的方法， 与赫伯特·舒尔伯格（Herbert C. Schulberg）博士，心理学，心理学教授， 和医学，匹兹堡大学医学院，作为教育者。 职业发展计划包括精神病和医学培训 流行病学，心理学，健康经济学和生物统计学。 计划的教程是“将行为干预措施整合到主要 医疗保健”和“评估精神病的成本效益 拟议的研究评估了 社会心理治疗和初级保健康复过程的功效 轻微抑郁症患者。 越来越多的证据表明主观良好的损害很大 存在和功能状况以及增加的医疗保健利用是 与轻微抑郁有关。然而，有效且可行的治疗 选项很少受到关注。一项随机，临床试验 在宾夕法尼亚州匹兹堡的四个城市卫生中心进行 检查护士提供的解决问题疗法（PST）的功效 小抑郁症患者的临床医生。这 将将护士临床医生提供的PST结果与 患者从主要护理中接受常规护理的结果 护理医师。护士提供的治疗的完整性将 在候选人期间进行评估 研究的启动阶段。 PST的功效将被评估 通过多个领域，包括症状和功能 治疗后的变化。假设接受的患者 PST比那些会显示出更大的症状和功能改善 接受平常的护理。此外，一项针对成本的试点研究 PST在轻度抑郁症患者中的有效性将 在奖励期内进行。