Developmental Core

发展核心

基本信息

批准号：
10215458
负责人：
Andrew Ddungu Kambugu
金额：
$ 23.99万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-13 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10215458
关键词：
AIDS related cancer Address Africa Africa South of the Sahara African Age Area Award Back California Caring Clinical Research Communicable Diseases Country Development Doctor of Philosophy Early Diagnosis Environment Foundations Funding Future Generations Grant HIV Health Sciences Home Individual Institutes Institution International Junior Physician K-Series Research Career Programs Leadership Malignant Neoplasms Malignant neoplasm of cervix uteri Mentors Mentorship Methodology Modeling Molds Pattern Phase Pilot Projects Prevention Principal Investigator Process Productivity Research Research Methodology Research Personnel Research Project Grants Research Support Resources San Francisco Scientist Stream Time Training Translational Research Uganda United States United States National Institutes of Health Universities Wages Writing anticancer research base career career development cohort college epidemiology study experience improved interest knowledge base programs prospective response skills virus related cancer

项目摘要

Creating an independent scientist requires extensive training within an enriching academic environment as well as adequate salary and research support for the trainee. The period that follows didactic graduate training is particularly vulnerable in East Africa, which is also true in sub-Saharan Africa as a whole. While funding streams exist for graduate training, the region lacks comprehensive mechanisms to support junior investigators as they transition towards research independence. In the U.S., post-graduate training is often facilitated by NIH "K Award" programs at both the individual and institutional level. NIH K Awards had been unavailable to African scientists but this recently changed with the creation of the K43 Emerging Global Leader Award. Yet, there still remains a substantial challenge preparing both trainees and their home institutions to compete for a K43 Award or other career development awards. To address the need for career development in the post-graduate period, the Developmental Core of the USEAHAMRC will: Aim 1. Bolster the overall environment for career development in clinical, epidemiologic and translational research at the East African institutions of our United States-East Africa HIV- Associated Malignancy Research Center (USEAHAMRC). Aim 2. Mentor and provide protected time for our emerging African and U.S. junior scientists working in the field of HIV-associated malignancies as they develop their academic and leadership portfolio and mature towards independence. Aim 3. Award funding for pilot research projects to be conducted by emerging African or U.S scientists. Modeled on institutional K Award programs in the U.S., we will create a semi-monthly Career Development Seminar featuring emphasis on scientific writing, mentorship skills, and foundational methodologic training for all interested scholars at our participating institutions (Aim 1). By drawing upon lessons learned from K Award funding in the U.S., four emerging Ugandan principal investigators will have a substantial portion of their time supported for the conduct of research in area of HIV-associated malignancies and will be mentored to compete for funding that will propel them to the next stage of their careers (Aim 2). With the assistance from substantial institutional commitment from UCSF, we will award two or three Pilot Project Awards annually over the 5-year funding cycle for research related to the USEAHAMRC research themes, which will help us identify and mentor the next cohort of junior investigators.

培养一名独立科学家需要在丰富的学术环境中进行广泛的培训以及为实习生提供足够的薪水和研究支持。教学毕业后的时期东非的培训尤其脆弱，整个撒哈拉以南非洲也是如此。尽管存在用于研究生培训的资金流，该地区缺乏支持初级人员的综合机制研究人员向研究独立过渡。在美国，研究生培训通常是由 NIH 在个人和机构层面的“K 奖”计划推动。 NIHK K 奖曾获得非洲科学家无法获得，但最近随着 K43 新兴全球项目的创建，这种情况发生了变化领袖奖。然而，为学员及其家庭做好准备仍然是一个巨大的挑战机构竞争 K43 奖或其他职业发展奖项。为了解决需要为了研究生阶段的职业发展，USEAHAMRC 的发展核心将：目标 1. 加强临床、流行病学和职业发展的整体环境我们美国东非机构的转化研究-东非艾滋病毒- 联合恶性肿瘤研究中心 (USEAHAMRC)。目标 2. 为非洲和美国新兴青年科学家提供指导并提供受保护的时间在与艾滋病毒相关的恶性肿瘤领域工作，同时发展他们的学术和领导组合并走向独立的成熟。目标 3. 为新兴非洲或美国开展的试点研究项目提供资金科学家。效仿美国机构 K 奖计划，我们将创建半月刊《职业发展》研讨会重点强调科学写作、指导技能和基础方法培训供我们参与机构的所有感兴趣的学者使用（目标 1）。借鉴K的经验教训在美国，四名新兴的乌干达首席研究员将获得很大一部分资助他们的时间用于开展与艾滋病毒相关的恶性肿瘤领域的研究，并将指导他们竞争资金，推动他们进入职业生涯的下一阶段（目标 2）。随着在加州大学旧金山分校的实质性机构承诺的帮助下，我们将授予两个或三个试点项目在 5 年资助周期内每年奖励与 USAHAMRC 研究主题相关的研究，这将帮助我们识别和指导下一批初级研究人员。