Understanding Perceptions of HIV Risk, PrEP, and PrEP use among African American Women Attending an HBCU

了解就读 HBCU 的非裔美国女性对 HIV 风险、PrEP 和 PrEP 使用的看法

基本信息

批准号：
10875004
负责人：
Cherise Baldwin Harrington
金额：
$ 22.61万
依托单位：
NORTH CAROLINA CENTRAL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-20 至 2025-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10875004
关键词：
Address Advisory Committees African American Area Automobile Driving Award Awareness Behavioral Behavioral Research Behavioral Sciences Biomedical Research Biotechnology COVID-19 COVID-19 disparity COVID-19 pandemic COVID-19 testing Collaborations Communities County Cues Data Development Disparity Dissemination and Implementation Doctor of Philosophy Economics Ecosystem Education Equity Evaluation Extramural Activities Fostering Funding Grant HIV risk Health Health Disparities Research Healthcare Historically Black Colleges and Universities Individual Infrastructure Institution Institutionalization International Investments Leadership Learning Mentors Minority Groups Mission National Institute of Environmental Health Sciences National Institute on Minority Health and Health Disparities North Carolina Perception Pilot Projects Postdoctoral Fellow Publications Renaissance Research Research Institute Research Personnel Research Project Grants Resolution Resource Sharing Resources Role Rural Scientist Social Distance Structural Racism United States National Institutes of Health Universities Vaccination Vaccines Woman Work behavioral health community engagement community organizations community partnership ethnic health disparity experience health disparity health equity health inequalities innovation interest malignant breast neoplasm meetings pandemic disease population health post-pandemic pre-exposure prophylaxis programs racial health disparity rural underserved tenure track underserved community urban underserved vaccine hesitancy virtual

项目摘要

Modified Project Summery/Abstract Section Despite advancements in HIV prevention and treatment, Black/African American women remain disproportionally affected by HIV infection. While many biological and behavioral factors shape women’s HIV risk at the individual level, social determinants of health including poverty, living in low-income communities, poor mental health, and lack of knowledge of and access to critical HIV prevention services including preexposure prophylaxis (PrEP) may drive this disproportionate burden. African American women are not only at increased risk but also have inequitable access to PrEP, particularly those living in low-income neighborhoods in the US South. Furthermore, few African American women, including students at HBCUs (many of whom grew up in low-income communities), are aware of PrEP. Although PrEP is highly effective in preventing the spread of HIV, only 10% of women in the US who could benefit from PrEP were prescribed it in 2019 (CDC, 2022). Increasing PrEP access is especially important for young women (under age 35), who experience 41% of all HIV infections among women. As HBCUs serve predominantly young women (64% of HBCU students were female in 2021) and many of their students come from low-income communities, HBCUs are an ideal context to reach an important population underserved by PrEP. To improve PrEP utilization among HBCU women, more research is needed to understand their low use of PrEP. Limited data exist about Black college women’s use of PrEP. Additionally, more African American HIV prevention researchers are needed because they may be more familiar with factors impacting Black communities due to their shared culture and life experiences. Thus, the primary goal of the proposed project is to engage and mentor African American female scholars from an HBCU in research to assess Black college women’s knowledge of and attitudes toward PrEP, perception of HIV risk, HIV testing behaviors, and likelihood of PrEP uptake. In service of this primary aim, the proposed project will also lay the foundation for a program of PrEP delivery research for these scholars, building on an existing community-based PrEP delivery program (IFE4Her). To adapt this program, we will conduct formative research to tailor a peer-based PrEP messaging campaign for HBCU women. These goals will be achieved through 2 Specific Aims: 1) To create and support a cadre of highly skilled African American HIV prevention researchers to address research gaps in the use of prevention strategies including PrEP, in African American communities, focusing on HBCUs. This aim will be achieved through a series of structured trainings and ongoing consultations and mentorship provided by UNC CFAR and associated faculty, longtime partners of the NCCU RCMI. 2)To adapt the IFE4Her peer-based PrEP communication strategy for HBCU women by conducting a mixed-methods (focus groups, key informant interviews, and surveys) tailoring study to understand PrEP knowledge, attitudes, messaging preferences, and delivery needs of African American women attending a HBCU. This study will catapult a body of research for highly promising RCMI investigators to develop HBCU-appropriate interventions to reduce HIV risk among women attending HBCUs.

修改的项目夏季/摘要部分尽管艾滋病毒预防和治疗方面取得了进步，但黑人/非洲裔美国妇女仍然存在受HIV感染的影响不成比例。虽然许多生物学和行为因素塑造了女性艾滋病毒在个人层面上的风险，包括贫困在内的社会决定者，生活在低收入社区中，精神健康不良，缺乏对包括预防预防的关键艾滋病毒预防服务（PREP）的知识和获得的知识可能会驱动这种不成比例的伯恩。非裔美国妇女不仅处于风险增加，而且还无法获得Prep，尤其是居住在美国南部低收入社区的人。此外，很少有非洲裔美国妇女，包括HBCUS的学生（许多人在低收入中长大，尽管PREP在预防艾滋病毒的传播方面非常有效，只有10％的妇女在2019年就处方了可以从PREP中受益的妇女（CDC，2022年，2022年的PROP ACCESS均对年轻女性（35岁以下的女性）尤其重要，而在35岁以下的女性中，所有妇女均为41％的人提供41％的妇女，这些妇女在41％的妇女中受到了HIV Invections的限制。（64％的HBCU学生是2021年的女性，他们的许多学生来自低收入社区，HBCU是一个理想的环境，可以通过PREP启动，以改善HBCU妇女的准备工作。共同的文化和生活经验。这一拟议项目的主要目标是从HBCU进行研究，以评估黑人大学妇女对预期的了解，对艾滋病毒风险的认识，艾滋病毒测试行为以及预备摄取的可能性。为了为这一主要目标服务，拟议的项目还将为这些学者的准备递送研究计划奠定基础，并以现有的基于社区的预备递送计划（IFE4HER）为基础。为了适应该计划，我们将进行形成性研究，以量身定制针对HBCU女性的基于同行的预备消息传递运动。这些目标将通过2个具体目标来实现：1）创建和支持一群高技能的非裔美国人艾滋病毒预防研究人员，以解决使用预防策略的研究差距，包括PREP，在非裔美国人社区，重点是HBCUS。该目标将通过一系列结构化培训以及NCCU RCMI的长期合作伙伴提供的一系列结构化培训以及持续的咨询和心态。 2）通过进行混合方法（焦点小组，关键线人访谈和调查）调整基于IFE4HER的同伴的预备沟通策略，以了解预期知识，态度，消息传递偏好以及参加HBCU的非裔美国妇女的交付需求。这项研究将为高度有希望的RCMI研究人员弹射一项研究，以开发适合HBCU的干预措施，以降低参加HBCU的妇女的HIV风险。

项目成果

期刊论文数量（10）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Food Insecurity in the Rural South in the Wake of the COVID-19 Pandemic.

COVID-19 大流行后南方农村地区的粮食不安全。

DOI：
10.18103/mra.v11i12.4593
发表时间：
2023
期刊：
Medical research archives
影响因子：
0
作者：
Taylor,LorraineC;Robinson,SerondaA;Doherty,IreneA;Giles,AkeylahC;Bauer,BrookeE;Pilkington,William
通讯作者：
Pilkington,William

Differential signalling induced by α7 nicotinic acetylcholine receptors in hippocampal dentate gyrus in vitro and in vivo.

DOI：
10.1113/jp280505
发表时间：
2021-10
期刊：
The Journal of physiology
影响因子：
0
作者：
Cheng Q;Lamb P;Stevanovic K;Bernstein BJ;Fry SA;Cushman JD;Yakel JL
通讯作者：
Yakel JL

Optimization and validation of a DYRK1A TR-FRET assay for high-throughput screening.

DOI：
10.1016/j.mex.2021.101383
发表时间：
2021
期刊：
MethodsX
影响因子：
1.9
作者：
Tarpley M;Caligan TB;Onyenwoke RU;Williams KP
通讯作者：
Williams KP

Proprotein Convertase Subtilisin Kexin 9 (PCSK9) and nonHDL particles rise during normal pregnancy and differ by BMI.

DOI：
10.1016/j.jacl.2022.05.070
发表时间：
2022-06
期刊：
Journal of clinical lipidology
影响因子：
4.4
作者：
R. Wild;E. Weedin;K. Cox;Y.D. Zhao;D. Wrenn;D. Lopez;C. Wooten;Q. Melendez;D. Myers;
通讯作者：
R. Wild;E. Weedin;K. Cox;Y.D. Zhao;D. Wrenn;D. Lopez;C. Wooten;Q. Melendez;D. Myers;

Identification of Novel Proteins Interacting with Proprotein Convertase Subtilisin/Kexin 9.