Strengthening behavioral and social science research capacity to address the evolving challenges in HIV care and prevention in Uganda

加强行为和社会科学研究能力，应对乌干达艾滋病毒护理和预防方面不断变化的挑战

• 批准号: 10872340
• 负责人: Carol Suzanne Camlin
• 金额: $ 10万
• 依托单位: MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-18 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10872340
• 关键词: Acceleration; Address; Ageism; Aging; Area; Behavioral; California; Caring; Collaborations; Complex; Data; Effectiveness; Elderly; Faculty; Fellowship; Future; HIV; Health; Intervention; Leadership; Master of Science; Mentorship; Nature; Older Population; Persons; Population; Postdoctoral Fellow; Prevention; Process; Productivity; Research; Research Personnel; Research Training; Resource-limited setting; Resources; San Francisco; Social isolation; Training; Training Programs; Uganda; Universities; antiretroviral therapy; behavioral and social science; biomedical scientist; collaborative environment; comorbidity; design; high risk; interest; next generation; programs; scale up; social; social science research; social stigma; success; Acceleration; Address; Ageism; Aging; Area; Behavioral; California; Caring; Collaborations; Complex; Data; Effectiveness; Elderly; Faculty; Fellowship; Future; HIV; Health; Intervention; Leadership; Master of Science; Mentorship; Nature; Older Population; Persons; Population; Postdoctoral Fellow; Prevention; Process; Productivity; Research; Research Personnel; Research Training; Resource-limited setting; Resources; San Francisco; Social isolation; Training; Training Programs; Uganda; Universities; antiretroviral therapy; behavioral and social science; biomedical scientist; collaborative environment; comorbidity; design; high risk; interest; next generation; programs; scale up; social; social science research; social stigma; success

Project summary: The effectiveness of and increased access to antiretroviral therapy (ART) has resulted in longer, healthier, and more productive lives for people living with HIV (PLHIV). However, this success presents unexpected consequences of a growing population of people aging with HIV. Challenges of aging with HIV include a high risk of co-morbidities, a double burden of intersectional stigma related to both aging and HIV, and an accelerated aging process. Previous research has shown that older PLHIV are more likely to be socially isolated. The intersection of HIV-related stigma and ageism is a complex issue requiring further research on the design and feasibility of implementing stigma reduction interventions. There is also an urgent need for research to address critical gaps in our understanding of the impacts of aging on the health of PLHIV and the nature of the accelerated aging process in PLHIV. There is therefore a need to train the next generation of researchers to address these challenges and to design, implement, and scale-up tailored and context-specific interventions for the growing population of older PLHIV in Uganda and similar resource-limited settings. In the past 4 years, we have established a comprehensive research-training program at Makerere University (Mak) with emphasis on strengthening leadership and expertise in Behavioral and Social Sciences Research (BSSR-D43TW011304) to address the evolving challenges in HIV care and prevention in Uganda. We have built on longstanding and productive collaborations between faculty at Mak and the University of California San Francisco (UCSF), to provide a suitable environment for interdisciplinary training in BSSR. We propose to continue the program and focus the next year and a renewal application to address the challenges of HIV and aging. We propose a one-year supplement to spur interest in research on HIV and aging and to obtain preliminary data to inform future long-term research training in this area. Specifically, we aim to: 1) broaden the MakBSSR training program to include research training on HIV and aging, ageism, and intersectional stigma, 2) provide research training and mentorship to masters and postdoctoral fellowship trainees to address the evolving challenges of HIV and aging in Uganda and, 3) prepare a renewal application of the MakBSSR research training program focused on aging with HIV, ageism and intersectional stigma. This supplement will leverage existing resources of the MakBSSR program including collaborations among social, behavioral, and biomedical scientists at Mak, collaborating HIV programs, and partner universities in the USA. During the one-year supplement, we plan to train one master’s degree candidate and two post-doctoral fellowship trainees, all at Mak.

项目摘要： 获得抗逆转录病毒疗法（ART）的有效性和增加的有效性已导致更长的时间 对艾滋病毒（PLHIV）患者更健康，更有生产力的生活。但是，这个成功呈现 越来越多的艾滋病毒衰老的人群的意外后果。艾滋病毒衰老的挑战 包括同事的高风险，与衰老和艾滋病毒相关的交叉污名的双重烧伤， 以及加速的衰老过程。先前的研究表明，较旧的PLHIV更有可能是 社会孤立。与HIV相关的污名与年龄歧视的交集是一个复杂的问题，需要进一步 对实施污名降低干预措施的设计和可行性的研究。还有一个 迫切需要研究以解决我们对衰老对健康的影响的关键差距 PLHIV和PLHIV加速衰老过程的性质。因此，有必要训练 下一代研究人员应对这些挑战并设计，实施和扩展 针对乌干达旧PLHIV不断增长的人群的量身定制和背景特定的干预措施和类似的干预措施 资源有限的设置。 在过去的四年中，我们在Makerere建立了一项全面的研究培训计划 大学（MAK）强调加强行为和社会领域的领导能力和专业知识 科学研究（BSSR-D43TW011304），以应对艾滋病毒护理和预防的不断发展的挑战 在乌干达。我们建立在Mak教职员工与产品之间的长期和产品合作建立 加利福尼亚大学旧金山大学（UCSF），为跨学科提供合适的环境 BSSR培训。我们建议继续该计划，并在明年集中精力，并续签申请 应对艾滋病毒和衰老的挑战。我们提出了一年的补充，以刺激研究 关于艾滋病毒和衰老，并获得初步数据，以告知该领域未来的长期研究培训。 具体而言，我们的目标是：1）扩大MAKBSSR培训计划，包括有关艾滋病毒和艾滋病毒的研究培训 衰老，年龄歧视和交叉污名，2）为硕士提供研究培训和心态 博士后奖学金学员应对乌干达艾滋病毒和衰老的不断发展的挑战，3） 准备MAKBSSR研究培训计划的更新应用，该计划旨在与HIV衰老， 年龄和交叉污名。该补充剂将利用MAKBSSR的现有资源 计划包括MAK的社会，行为和生物医学科学家之间的合作，合作 艾滋病毒计划和美国的合伙大学。在一年的补充期间，我们计划培训一个 硕士学位候选人和两名博士后奖学金学员，都在Mak。