Creating and Optimizing Mindfulness Measures to Enhance and Normalize Clinical Evaluation (COMMENCE)

创建和优化正念措施以增强和规范临床评估（COMMENCE）

基本信息

批准号：
9364754
负责人：
CAROL MARIE GRECO
金额：
$ 79.63万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-07-15 至 2022-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9364754
关键词：
Address Assessment tool Attention Attitude Awareness Body measure procedure Calibration Characteristics Chicago Clinical Clinical Research Cognitive Communities Confusion Development Device or Instrument Development Dimensions Emotions Esthesia Evaluation Focus Groups Funding Future General Population Gold Health Health behavior Individual Information Systems Integrative Medicine Intervention Intervention Studies Intervention Trial Interview Length Life Link Literature Measurement Measures Meditation Methodology Methods Outcome Participant Patient Outcomes Assessments Patient Self-Report Performance Persons Procedures Process Psychometrics Public Health Publications Quality of life Reaction Reporter Reproducibility Research Research Design Research Personnel Review Literature Sampling Self Care Site Standardization Stress Students Surveys System Techniques Testing Thinking Time United States United States National Institutes of Health Validation Walking Writing arm base behavioral/social science body-mind clinical efficacy clinically relevant computerized educational atmosphere experience flexibility improved innovation instructor instrument intervention program member method development mindfulness mindfulness intervention mindfulness meditation mindfulness-based stress reduction person centered post intervention practice-based research network programs research clinical testing response skills teacher theories tool

项目摘要

PROJECT SUMMARY/ABSTRACT BACKGROUND: Mindfulness-Based Interventions (MBIs) have a prominent place in public health and clinical research, and are the focus of hundreds of NIH-funded trials. Nevertheless, significant gaps exist in how mindfulness is measured as a construct using currently available self-reported outcomes instruments. Due to the sheer number of available mindfulness measurement tools, each measuring different concepts in different ways, it has become difficult to establish whether MBI participants actually develop mindfulness skills and attitudes, and whether health outcomes can be attributed to gains in mindfulness. Further, it is not possible to compare findings from one mindfulness trial with another using the same measurement metric. The Patient Reported Outcomes Measurement Information System (PROMIS) has established a rigorous and systematic instrument development methodology that draws from qualitative, quantitative and advanced psychometric approaches to create brief, precise, flexible, standardized, and clinically-relevant outcomes tools. Further, PROMIS-related applications such as PROsetta Stone, have enabled psychometric score linking between PROMIS and legacy measures using sophisticated cross-walk analytic techniques. OBJECTIVE: To improve the rigor, relevance, and reproducibility of MBI research results by applying PROMIS and PROsetta Stone instrument development methodologies to the field of mindfulness measurement. STUDY DESIGN: We will accomplish our study through the following three aims and related development and analysis activities: AIM 1. Development of New Mindfulness Item Banks. This will include: 1) a literature review, 2) online survey of mindfulness researchers (n=50); 3) individual interviews (n=20) and focus groups (n=48 participants) with new and experienced meditators; 4) item writing and refinement; 6) translatability review; and 7) cognitive interviews (n=30) with mindfulness instructors and community members. AIM 2. Calibration of New Mindfulness Item Banks and Score Linking with Legacy Measures. This will include: 1) testing new mindfulness item banks in a large online general population sample (n=4200) and online sample of mindfulness teachers and students (n=500); 2) evaluating dimensionality and other Item Response Theory (IRT) assumptions; 3) Conducting IRT analyses; and 4) Creating computerized adaptive tests (CATs) and fixed length short forms; 5) Linking new mindfulness item banks with legacy mindfulness measures and creating scoring cross walk tables (n=3000). AIM 3. Validation of New Mindfulness Short Forms in Ongoing Mindfulness Courses. For Classic Test Theory-based validation outcomes (e.g., construct and criterion-related validity), responsiveness to change, and estimation of minimally important differences, we will administer new mindfulness short forms, legacy measures, and a performance-based experiential mindfulness task at baseline, 8-weeks, and 16 weeks in multiple, on-going 8-week MBI courses programs occurring throughout the United States (n=250). RELEVANCE: Applying PROMIS and PROsetta Stone methods to mindfulness measurement could have a major impact on mindfulness research through increasing measurement precision, standardization, and comparability across and between studies: past, present, and future.

项目概要/摘要背景：基于正念的干预（MBI）在公共卫生和临床中具有突出的地位研究的重点，也是 NIH 资助的数百项试验的重点。然而，在如何运用正念方面存在重大差距使用当前可用的自我报告结果工具作为构建进行测量。由于数量庞大可用的正念测量工具，每种工具都以不同的方式测量不同的概念，因此很难确定 MBI 参与者是否真正培养了正念技能和态度，以及健康结果是否可以归因于正念的收获。此外，不可能将一项正念试验的结果与另一项试验的结果进行比较使用相同的测量指标。患者报告结果测量信息系统 (PROMIS) 建立了严格、系统的仪器开发方法，该方法借鉴了定性、定量和先进的心理测量方法可创建简洁、精确、灵活、标准化和临床相关的结果工具。此外，PROSetta Stone 等与 PROMIS 相关的应用程序已启用心理测量分数使用复杂的人行横道分析技术的 PROMIS 和遗留测量。目的：通过应用 PROMIS 和 PROsetta Stone 正念测量领域的仪器开发方法。研究设计：我们将通过以下三个目标以及相关的开发和分析来完成我们的研究活动：目标 1. 开发新的正念项目库。这将包括：1）文献综述，2）在线正念研究人员调查（n=50）； 3) 个人访谈（n=20）和焦点小组（n=48 参与者）和经验丰富的冥想者； 4）项目撰写和细化； 6）可译性审查； 7) 认知访谈 (n=30) 与正念导师和社区成员一起。 AIM 2. 新正念项目库和分数的校准与旧措施的链接。这将包括：1）在大型在线综合测试中测试新的正念项目库人口样本（n=4200）和正念师生在线样本（n=500）； 2）评估维数和其他项目反应理论 (IRT) 假设； 3）进行IRT分析； 4) 创造计算机化适应性测试（CAT）和固定长度的简表； 5）将新的正念项目库与传统项目库联系起来正念测量并创建步行评分表 (n=3000)。 AIM 3. 新正念短片的验证持续正念课程的形式。对于基于经典测试理论的验证结果（例如，构造和标准相关的有效性）、对变化的响应以及对最小重要差异的估计，我们将管理新的正念简短形式、遗留措施和基于绩效的体验式正念任务在整个美国开展的多个持续 8 周 MBI 课程项目中的基线、8 周和 16 周州（n=250）。相关性：将 PROMIS 和 PROsetta Stone 方法应用于正念测量可以通过提高测量精度、标准化和研究之间的可比性：过去、现在和未来。