Core A: Administrative

核心A：行政

基本信息

批准号：
10617344
负责人：
James L Riley
金额：
$ 8.15万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-05-15 至 2025-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10617344
关键词：
Acquired Immunodeficiency Syndrome Adherence Administrator Advisory Committees Annual Reports Award BLT mice Basic Science Biometry Budgets CAR T cell therapy Clinical Clinical Trials Communication Congresses Ensure Genome Goals Guidelines HIV HIV-1 Home Human Resources Immunology Individual Laboratories Logistics Mission Modeling Modification Monitor National Institute of Allergy and Infectious Disease Occupational activity of managing finances Outcome Pharmacologic Substance Phase I Clinical Trials Preparation Principal Investigator Private Sector Productivity Progress Reports Publications Reporting Research Research Personnel Resource Allocation Scientist Structure T cell response T-Lymphocyte Testing Therapeutic United States National Institutes of Health Viral reservoir Work antiretroviral therapy bench to bedside clinical center clinical epidemiology clinical trial implementation data management data sharing design engineered T cells experience innovation manufacturing process meetings novel strategies preclinical evaluation programs targeted nucleases timeline tool trafficking working group

项目摘要

CORE A: ABSTRACT Core A will be responsible for providing administrative and biostatistics support for the overall program project. The Core will interact with Program management at NIAID and with the external Scientific Advisory Panel, coordinating meetings and progress reports. Budget reports and annual reports to NIH and FDA will be coordinated by Core A. It will also serve to amalgamate the investigators, their experimental findings and their ideas, evaluation of pre- clinical and clinical efforts to focus efforts on enhancing the clinical outcome. The administrative functions will be accomplished using a structure in which the Core Leader, Dr. Riley, is advised by an Executive Committee of Project and Core Leaders with input from the Scientific Advisory Committee. The finances and meeting logistics of the U19 will be organized by Ms. Chelsey Molineaux who will meet monthly with the U19 PI and each Project and Core Leader. Dr. Shaw will provide comprehensive biostatistics support for the scientific project and core, and for the design and implementation of the clinical trial. Therefore, the specific aims are: SA1: To coordinate the interactions among scientists, private sector partners, and NIH personnel regarding efficient implementation of proposed plans and projects. SA2: To oversee all budgetary matters, including monitoring of monthly expenses and preparation of non-competitive renewal applications. SA3: To provide statistical support for projects, especially the proposed clinical trial in Project 4

核心A：摘要核心A将负责为整体提供行政和生物统计学支持计划项目。核心将与NIAID的计划管理互动，并与外部科学咨询小组，协调会议和进度报告。预算报告向NIH和FDA向NIH和FDA的年度报告将由Core A进行协调。将研究人员合并，他们的实验发现及其思想，评估前临床和临床努力将精力集中在增强临床结果上。行政将使用建议核心负责人莱利博士的结构来实现功能由项目和核心领导者执行委员会，并通过科学咨询的意见委员会。 U19的财务和会议后勤将由Chelsey女士组织 Molineaux将每月与U19 PI和每个项目和核心负责人见面。肖博士将为科学项目和核心提供全面的生物统计学支持，并为临床试验的设计和实施。因此，具体目的是： SA1：协调科学家，私营部门合作伙伴和NIH之间的互动关于有效实施拟议计划和项目的人员。 SA2：监督所有预算事项，包括监视每月费用和制备非竞争性更新应用。 SA3：为项目提供统计支持，尤其是项目4的拟议临床试验