Georgia CTSA Research Supplement to Promote Diversity in Health-Related Research (Hernandez)

佐治亚州 CTSA 研究增刊促进健康相关研究的多样性 (Hernandez)

• 批准号: 9815750
• 负责人: HENRY M BLUMBERG
• 金额: $ 3.46万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-24 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9815750
• 关键词: Address; Affect; Behavior; Clinical; Clinical Research; Clinical Sciences; Communities; Community Health Aides; Doctor of Philosophy; Ethnic group; Growth; Health; Hispanics; Immigrant; Intervention; Knowledge; Latina; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Mentorship; Methods; Mexican; Minority; Modeling; Prevention Research; Preventive; Principal Investigator; Research; Research Proposals; Role; Rural; Stress; System; Training; Translational Research; Vulnerable Populations; Woman; Work; anticancer research; base; cancer diagnosis; cancer health disparity; cancer prevention; career; cervical cancer prevention; contextual factors; experience; improved; innovation; outreach; parent grant; programs; public health relevance; racial and ethnic; rural area; rural underserved; trend

Program Director/Principal Investigator (Last, First, Middle): Taylor, W. Robert Project Summary/Abstract This diversity supplement builds upon the work of the Georgia Clinical and Translational Science Alliance (Georgia CTSA) (ULTR002378) parent grant by conducting translational research and better engaging rural and underserved Georgia Latinas in cervical cancer prevention, and participation in cancer clinical research. Latina women are disproportionately impacted by cervical cancer in comparison to women from other racial/ethnic groups. In the state of Georgia, this national trend remains as Latinas are disproportionately affected by higher rates of cervical cancer diagnoses compared to non-Latina black and white women. Although studies have identified facilitators to cervical cancer prevention among Latinas, they are narrow in scope and don't address Latinas residing in rural areas and the boarder contextual factors that may prohibit women from participating in prevention and clinical research. Using community engaged approaches applied through a minority stress framework, the objective of this research proposal is to identify and improve our understanding of the facilitators and barriers to cervical cancer prevention, and participation in cancer clinical research among rural Mexican immigrant Latinas in Georgia. Using a mixed-methods approach, the specific aims include: Aim 1a: To identify the facilitators and barriers of cervical cancer prevention methods among rural Latina women in Georgia; Aim1b: To investigate the role of promotoras (community health workers) and other community-based, cancer prevention opportunities and outreach strategies to decrease cervical cancer disparities; and Aim 2: To assess factors associated with Latina participation in clinical cervical cancer research. Hypothesis: Immigrant related minority stress factors will significantly decrease the likelihood of preventive behaviors, and participation in clinical research among rural Latina immigrants. This study is significant because Latina women simultaneously experience the greatest burden of cervical cancer health disparities and are the fastest growing major demographic in the U.S, thus this growth may exacerbate the burden of cervical cancer. The research is innovative because it: (1) focuses on a largely rural, underserved, vulnerable population with unique and specific needs; (2) uses the Minority Stress Model that has not being applied in cancer research; and (3) engages the community as a part of the interdisciplinary team. Research findings will be used to inform to inform community and system-level approaches to address a persistent disparity. OMB No. 0925-0001/0002 (Rev. 01/18 Approved Through 03/31/2020) Page Continuation Format Page

项目总监/首席研究员（最后、第一、中间）：Taylor, W. Robert 项目概要/摘要 该多样性补充以佐治亚州临床和转化科学的工作为基础 联盟（乔治亚州 CTSA）（ULTR002378）通过开展转化研究和更好的家长资助 让农村和服务不足的佐治亚州拉丁裔参与宫颈癌预防，并参与 癌症临床研究。拉丁裔女性受宫颈癌的影响尤为严重 与其他种族/族裔群体的妇女进行比较。在乔治亚州，这种全国趋势 仍然存在，因为拉丁裔受宫颈癌诊断率较高的影响不成比例 与非拉丁裔黑人和白人女性相比。尽管研究已经确定了促进者 拉丁裔的宫颈癌预防，范围狭窄且不针对拉丁裔 居住在农村地区和寄宿家庭的环境因素可能会阻碍妇女参与 从事预防和临床研究。使用少数人采用的社区参与方法 压力框架，本研究计划的目的是确定并提高我们的理解 宫颈癌预防和参与癌症临床的促进因素和障碍 对佐治亚州农村墨西哥移民拉丁裔的研究。使用混合方法的方法， 具体目标包括： 目标 1a：确定宫颈癌预防的促进因素和障碍 格鲁吉亚农村拉丁裔妇女的方法；目标 1b：研究启动子的作用 （社区卫生工作者）和其他基于社区的癌症预防机会和 减少宫颈癌差异的外展策略；目标 2：评估相关因素 与拉丁裔参与临床宫颈癌研究。假设：与移民有关的少数群体 压力因素会显着降低预防行为和参与的可能性 农村拉丁裔移民的临床研究。这项研究意义重大，因为拉丁裔女性 同时经历着宫颈癌健康差异的最大负担，并且是 美国主要人口增长最快，因此这种增长可能会加剧 宫颈癌。这项研究具有创新性，因为它：(1) 重点关注农村地区、服务不足、 具有独特和具体需求的弱势群体； (2) 使用少数民族压力模型 应用于癌症研究； (3) 让社区参与跨学科研究 团队。研究结果将用于为社区和系统级方法提供信息 解决持续存在的差距。 OMB 编号 0925-0001/0002（修订版 01/18 批准至 03/31/2020） 页面延续格式页面