HCHS-SOL AE FIELD CENTER DIVERSITY SUPPLEMENT FOR DR. TREJO

HCHS-SOL AE 现场中心多样性补充 DR.

• 批准号: 10953884
• 负责人: ROBERT KAPLAN
• 金额: $ 10.89万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-15 至 2023-11-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10953884
• 关键词: HCHS; SOL; AE; FIELD; CENTER

The primary goals for the HCHS baseline study are to examine the prevalence and development of disease in Hispanics/Latinos, the role of acculturation, and to identify risk factors that play protective or harmful roles in Hispanics/Latinos. This project will leverage the HCHS data to examine the genetic risk of suspected nonalcoholic fatty liver disease in Hispanic/Latino populations and to examine differences by genetic ancestry. It will expands on previous HCHS work in the area of the genetics of liver disease, while making the novel contribution of a multicohort pooling project to enhance statistical power and increase generalizability of findings. Dr. Trejo's specific research activities for this supplemental application will involve conducting data analyses, manuscript preparation using data available from the parent study, and genetic data management and analysis that will expand on his previous work.

HCHS基线研究的主要目标是检查西班牙裔/拉丁美洲人的疾病的流行和发展，适应的作用，并确定在西班牙裔/拉丁美洲人中起保护性或有害作用的危险因素。该项目将利用HCHS数据来检查西班牙裔/拉丁裔人群中可疑的非酒精性脂肪肝病的遗传风险，并通过遗传血统检查差异。它将扩大以前的HCHS在肝病遗传学领域的工作，同时为增强统计能力并提高发现的普遍性的多胡子聚集项目的新贡献。 Trejo博士针对此补充应用的特定研究活动将涉及进行数据分析，使用父母研究中可用的数据以及遗传数据管理的手稿准备 和分析将扩大他以前的工作。