Near-infrared spectroscopy and electroencephalography to assess cortical activation during motor tasks in infants and toddlers with or at high-risk for Cerebral Palsy and Autism Spectrum Disorder comp

近红外光谱和脑电图用于评估患有脑瘫和自闭症谱系障碍或具有高风险的婴儿和幼儿运动任务期间的皮质激活

• 批准号: 10928554
• 负责人: DIANE L. DAMIANO
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10928554
• 关键词: 1 year old; 3 year old; Adult; Age; Age Years; Area; Body Weight; Brain; Cerebral Palsy; Child; Childhood; Communities; Contracts; Cross-Sectional Studies; Data; Data Analyses; Data Collection; Dedications; Development; Devices; Electroencephalography; Enrollment; Family; Force of Gravity; Foundations; Friction; Hand; Infant; Intervention; Laboratories; Leg; Life; Limb structure; Mediation; Motor; Motor Skills; Movement; Near-Infrared Spectroscopy; Pattern; Rehabilitation therapy; Research; Toddler; Toy; United States National Institutes of Health; Visit; Weight-Bearing state; Work; autism spectrum disorder; coronavirus disease; disability; grasp; high risk; infancy; longitudinal analysis; mobility aid; nervous system disorder; recruit; response; treadmill; walker; web site

This project was severely impacted by COVID. We had collected data on multiple infants from 2018-2020, but has been very slow since we restarted enrollment in summer of 2022. We have dedicated considerable effort to recruitment this past year by visiting and connecting with local therapists who work with infants, distributing flyers to practitioners as well as in the surrounding community. We connected with a CP foundation who has a research website where they have posted our study information and after several months of negotiating and seeking approval at NIH, we entered into a contract with NextDoor to try and reach young families in the greater DC metro area. We hope that these efforts will boost recruitment soon because our early data showed that we could get reliable brain activation data in infants under a year of age during fundamental motor tasks such as reaching and stepping.

该项目受到Covid的严重影响。从2018 - 2020年开始，我们已经收集了多个婴儿的数据，但是自2022年夏天重新启动入学以来，我们一直非常慢。过去一年来，我们付出了巨大的努力来招募并与与婴儿合作，分发飞行者分发的当地治疗师并建立联系。向从业人员以及周围的社区致敬。我们与CP基金会建立了联系，该基金会拥有一个研究网站，他们在其中发布了我们的研究信息，经过几个月的谈判和寻求NIH的批准，我们与Nextdoor签订了合同，试图在更大的DC Metro地区与年轻家庭联系。我们希望这些努力将很快促进招聘，因为我们的早期数据表明，在诸如达到和步步之类的基本运动任务期间，我们可以在一岁以下的婴儿中获得可靠的大脑激活数据。