University of Cincinnati NETT Network Hub and Spoke System

辛辛那提大学 NTT 网络中心辐射系统

• 批准号: 8700547
• 负责人: Opeolu M Adeoye
• 金额: $ 30.1万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-03 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8700547
• 关键词: Acute; Acute Disease; Advisory Committees; Affect; Caring; Chairperson; Characteristics; Clinical; Clinical Research; Clinical Trials; Committee Members; Communication; Communities; Complex; Conduct Clinical Trials; Continuity of Patient Care; Data; Data Quality; Disclosure; Disease; Effectiveness; Electronics; Eligibility Determination; Emergency Department Physician; Emergency Situation; Emergency treatment; Enrollment; Environment; Ethics; Failure; Funding; Goals; Health; Health system; Hospitals; Human Resources; Injury; Institutional Review Boards; Kentucky; Learning; Medicine; Metric; Monitor; National Institute of Neurological Disorders and Stroke; Neurologic; Neurological emergencies; Neurologist; Neurology; Neurosurgeon; Nurses; Outcome; Participant; Patient Recruitments; Patients; Persons; Physician Executives; Population; Positioning Attribute; Process; Protocols documentation; Provider; Randomized; Recruitment Activity; Rehabilitation therapy; Reporting; Request for Applications; Research; Research Design; Research Infrastructure; Research Personnel; Resolution; Site; Summary Reports; Symptoms; System; Training; Trauma; Universities; base; clinical research site; college; community consultation; data management; design; experience; flexibility; implementation trial; improved; meetings; multidisciplinary; nervous system disorder; neurosurgery; operation; patient population; screening; success; treatment trial; willingness; working group

DESCRIPTION (provided by applicant): The Neurological Emergencies Treatment Trials (NETT) Network has successfully established a clinical research network including emergency physicians, neurologists and neurosurgeons. The network's goals are to efficiently develop better treatments for patients with acute neurological disorders through execution of NINDS-sponsored clinical trials (RFA-NS-06-002). The essential aim of the NETT Network is to expedite recruitment into clinical trials. The Greater Cincinnati/Northern Kentucky NETT Hub and Spoke System was one of seventeen original Clinical Site Hubs funded under the 2006 Request for Applications. To date, our Cincinnati NETT Hub and Spoke System has enrolled over 226 patients in trials being conducted through the NETT Network. This positions us as the 2nd highest enroller among NETT Hubs. In this renewal application, we build on the success of our existing Hub and Spoke System with the following specific aims: #1) Efficiently recruit and retain participants and optimize data quality in NETT trials; and, #2) Actively contribute to the overall success of the NETT Network. To achieve these aims, we have identified four key ingredients that contribute to our continued success. These include: strong and ongoing institutional and community support; access to a demographic representative of the populations to which results must be generalized; unfiltered access to the full spectrum of acute neurologic disease and injury; and, active participation in and contributory to the efforts of the NETT Network. In this competitive renewal application, we demonstrate the strong and unwavering support of key players at our Hub including the Dean of the College of Medicine and the CEO of our Hub hospital. Further, we show a strong, multidisciplinary commitment to the success of our Hub and Spoke System embodied in our Advisory Committee members which include the Chairmen of Neurology and Neurosurgery, the PI of our CTSA, the Director of the Division of Trauma, and the COO of a large health system in Greater Cincinnati whose purview includes five of our Spoke hospitals. In addition to the high level support we receive from Institutional an community leaders, we demonstrate our ability to access the appropriate patient populations by presenting data on the relevant disease processes and showing the unyielding support we have from 'boots-on-the-ground' personnel from Medical Directors to bedside nurses. We have and will continue to be actively engaged in all NETT Network activities in order to learn how we may continue to optimize our Hub and Spoke System while also sharing our experience in ways that may be beneficial to other Hubs.

描述（由申请人提供）：神经急症治疗试验（NETT）网络已成功建立了一个包括急诊医师、神经科医生和神经外科医生的临床研究网络。该网络的目标是通过执行 NINDS 赞助的临床试验 (RFA-NS-06-002)，有效地为患有急性神经系统疾病的患者开发更好的治疗方法。 NTT 网络的基本目标是加快临床试验的招募。大辛辛那提/北肯塔基州 NTT 中心辐射系统是 2006 年申请资助的 17 个原始临床站点中心之一。迄今为止，我们的辛辛那提 NTT 中心辐射系统已招募了超过 226 名患者参加通过 NETT 网络进行的试验。这使我们成为 NTT 中心中第二高的注册者。在此更新应用程序中，我们以现有轮辐系统的成功为基础，实现以下具体目标：#1) 有效招募和留住参与者，并优化 NETT 试验中的数据质量； #2) 积极为 NTT 网络的整体成功做出贡献。 为了实现这些目标，我们确定了有助于我们持续成功的四个关键因素。 其中包括： 强有力且持续的机构和社区支持；获得必须将结果推广到的人口的人口代表；未经过滤地了解所有急性神经系统疾病和损伤；积极参与并为 NTT 网络的工作做出贡献。在这个竞争激烈的续签申请中，我们展示了我们中心关键参与者的强大和坚定的支持，包括医学院院长和我们中心医院的首席执行官。此外，我们对中心辐射系统的成功表现出强有力的多学科承诺，这体现在我们的咨询委员会成员中，其中包括神经病学和神经外科主席、CTSA 的 PI、创伤科主任和首席运营官大辛辛那提大型卫生系统的管辖范围包括我们的五家 Spoke 医院。除了我们从机构和社区领导人那里获得的高水平支持外，我们还通过提供相关疾病过程的数据并展示我们从“脚踏实地”获得的坚定支持，展示了我们接触适当患者群体的能力从医疗主任到床边护士的人员。我们已经并将继续积极参与所有 NETT 网络活动，以便了解我们如何继续优化我们的中心辐射系统，同时以可能有益于其他中心的方式分享我们的经验。