Fellowship in Biological Psychiatry and Neuroscience

生物精神病学和神经科学研究员

基本信息

批准号：
10621897
负责人：
Pei-an (Betty) Shih
金额：
$ 22.97万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
1986
资助国家：
美国
起止时间：
1986-07-15 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10621897
关键词：
Biological Psychiatry Fellowship Neurosciences

项目摘要

Project Summary Neuroscience is among the fastest growing area of science and has produced remarkable developments that will have profound implications for the understanding and treatment of mental disorders. Innovations and advancements in molecular genetics, brain imaging methods, molecular biology and have resulted in unprecedented advances that have extended visions of understanding and treating psychiatric disorders to the hope of preventing and even curing them. However, there is still a gap in applying knowledge and tools to psychiatric disorders that is due, in part, to a shortage of clinical and translational-science researchers. Consequently, it is imperative train researchers to translate important basic science findings into clinically relevant treatments. This competitive renewal application requests continued NIMH funding for the long-standing, successful University of California, San Diego (UCSD) Fellowship in Biological Psychiatry and Neuroscience. The Fellowship is designed for provide education, research training, and career opportunities for 7 post-doctoral fellows with a particular emphasis on candidates that are focused on using biological tools to understand pathophysiology and brain processes of psychiatric illness and develop potential treatments for these disorders. The overall goal is to train fellows from diverse backgrounds to acquire the skills necessary for the conceptualization, planning, conduct and publication of research in biological psychiatry and neuroscience with the ultimate goal to become independent and funded researchers. Specific goals of the Fellowship are: (1) To recruit a diverse group of highly accomplished fellows for advanced research training (2) To provide a high level of training necessary for successful transition into an independent research career, which is focused on: a) Ethical conduct of research and research ethics; b) General methodologies applicable to research in biological psychiatry and neuroscience; c) Use of data science in research; d) Methods to improve reproducibility of results; e) Specific approaches relevant for the fellow's individual research project; f) Training in scientific writing directed at production of scientific papers and grant applications.; g) Grant writing skills and education regarding NIH procedures (3) To enable the fellow to conduct and complete a specific research project that can be viewed as a seed for an independent research career trajectory and includes: a) Proposal of a research project based on NIH forms and guidelines; b) Implementation of this project with a UCSD-affiliated mentor, and c) Regular monitoring and evaluation of research progress. (4) To provide practical advice and support for career development, which includes: a) Opportunities for fellows to present their projects and peer-review grant applications, and practice grant review as a mock reviewer through mandatory attendance of the weekly didactic session; b) Explicate milestones and career guidelines that are written in the T32 Individual Development Plan (IDP); c) Network with senior researchers within UCSD and other organizations, and via online resources; d) Fellows have regular one-on-one meetings with directors for scientific and career development related mentoring and support.

项目概要神经科学是发展最快的科学领域之一，并取得了显着的发展，将对精神障碍的理解和治疗产生深远的影响。创新和分子遗传学、脑成像方法、分子生物学的进步导致前所未有的进步将理解和治疗精神疾病的视野扩展到了希望能够预防甚至治愈它们。然而，在知识和工具的应用方面仍然存在差距。精神疾病的部分原因是缺乏临床和转化科学研究人员。因此，必须培训研究人员将重要的基础科学发现转化为临床相关治疗。此竞争性更新申请要求 NIMH 继续为长期、成功的项目提供资金加州大学圣地亚哥分校 (UCSD) 生物精神病学和神经科学奖学金。这奖学金旨在为 7 名博士后提供教育、研究培训和职业机会特别强调专注于使用生物工具来理解的候选人的研究员精神疾病的病理生理学和大脑过程，并开发这些疾病的潜在治疗方法失调。总体目标是培训来自不同背景的研究员，以获得必要的技能生物精神病学和神经科学研究的概念化、规划、实施和出版最终目标是成为独立并受资助的研究人员。该奖学金的具体目标是： (1) 招募一批多元化的高水平研究员进行高级研究培训 (2) 提供成功转型为独立研究所需的高水平培训职业生涯，重点关注： a) 研究道德行为和研究伦理； b) 一般方法适用于生物精神病学和神经科学研究； c) 在研究中使用数据科学； d) 提高结果再现性的方法； e) 与研究员个人相关的具体方法研究项目； f) 旨在撰写科学论文和资助的科学写作培训应用程序。； g) 授予有关 NIH 程序的写作技巧和教育 (3) 使研究员能够开展并完成一项特定的研究项目，该项目可被视为独立研究职业轨迹的种子，包括： a) 基于的研究项目提案关于 NIH 表格和指南； b) 与 UCSD 附属导师一起实施该项目，以及 c) 定期监测和评估研究进展。 (4) 为职业发展提供切实可行的建议和支持，其中包括：研究员展示他们的项目和同行评审拨款申请，并模拟拨款评审通过强制参加每周的教学会议来进行审查； b) 阐明里程碑和职业生涯 T32 个人发展计划 (IDP) 中写入的指南； c) 与资深研究人员建立联系在加州大学圣地亚哥分校和其他组织内，以及通过在线资源； d) 研究员定期举行一对一会议与科学和职业发展相关的指导和支持主管。

项目成果

期刊论文数量（271）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Functioning of neural systems supporting emotion regulation in anxiety-prone individuals.

DOI：
10.1016/j.neuroimage.2010.07.041
发表时间：
2011-01-01
期刊：
NEUROIMAGE
影响因子：
5.7
作者：
Campbell-Sills, Laura;Simmons, Alan N.;Lovero, Kathryn L.;Rochlin, Alexis A.;Paulus, Martin P.;Stein, Murray B.
通讯作者：
Stein, Murray B.

Subjective cognitive complaints contribute to misdiagnosis of mild cognitive impairment.

DOI：
10.1017/s135561771400068x
发表时间：
2014-09
期刊：
Journal of the International Neuropsychological Society : JINS
影响因子：
0
作者：
Edmonds EC;Delano-Wood L;Galasko DR;Salmon DP;Bondi MW;Alzheimer’s Disease Neuroimaging Initiative
通讯作者：
Alzheimer’s Disease Neuroimaging Initiative

Searching for host immune-microbiome mechanisms in obsessive-compulsive disorder: A narrative literature review and future directions.

DOI：
10.1016/j.neubiorev.2021.02.034
发表时间：
2021-06
期刊：
Neuroscience and biobehavioral reviews
影响因子：
8.2
作者：
Troyer EA;Kohn JN;Ecklu-Mensah G;Aleti G;Rosenberg DR;Hong S
通讯作者：
Hong S

Sleep loss activates cellular inflammation and signal transducer and activator of transcription (STAT) family proteins in humans.

DOI：
10.1016/j.bbi.2014.09.017
发表时间：
2015-07
期刊：
BRAIN BEHAVIOR AND IMMUNITY
影响因子：
15.1
作者：
Irwin, Michael R.;Witarama, Tuff;Caudill, Marissa;Olmstead, Richard;Breen, Elizabeth Crabb
通讯作者：
Breen, Elizabeth Crabb

Modified Mediterranean Diet for Enrichment of Short Chain Fatty Acids: Potential Adjunctive Therapeutic to Target Immune and Metabolic Dysfunction in Schizophrenia?