UAB-HudsonAlpha Genomic Medicine Training Program

UAB-HudsonAlpha 基因组医学培训计划

• 批准号: 10627848
• 负责人: Gregory Stefan Barsh
• 金额: $ 18.68万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627848
• 关键词: Genomic medicine; Training Programs

Project Summary The UAB-HudsonAlpha Genomic Medicine Training Program was established four years ago to train leaders in the integration of genetics and genomics into medical practice. We have recruited fellows with an MD, PhD, or PharmD degree who participate in customized educational training and pursue mentored research at UAB or HudsonAlpha. The educational plan is based on a set of competencies that equip the trainee with the knowledge and skill set to be an independent genomic medicine researcher. Each trainee also completes a genomic medicine practicum that provides exposure to clinics and clinical laboratories, an educational outreach project, an opportunity to explore entrepreneurship career opportunities, and training in the responsible conduct of research and rigor and reproducibility in research. The trainees carry out mentored research under the auspices of one of 60 program faculty, as part of an individualized development plan. Conferences at UAB and HudsonAlpha include research seminars, genome sequencing case review conferences, a molecular tumor board, and a monthly genomic medicine meeting, which provide a foundation and common platform for all trainees. All trainees attend the annual NHGRI training conference and present either posters or platform presentations and present their work at a Work in Progress seminar at UAB. Trainee progress is monitored in biannual written reports and meetings with each trainee and mentor together with the program co-directors. Several innovations have been instituted since the inception of the program four years ago. These include the monthly genomic medicine conference and the entrepreneurship practicum; the latter leverages the strong relationship of HudsonAlpha with biotechnology companies hosted on the HudsonAlpha campus. In order to increase our ability to recruit MDs, we have forged relationships with the UAB Department of Surgery and Department of Medicine, both of which have programs that enable residents to pursue two or more years of research during the course of their training. We have also added an introductory lecture series on the basics of genomic medicine to ensure that all trainees are equipped with basic skills in genomic medicine, including, for example, data management and sharing. The required education in Rigor and Reproducibility in Research is also a new addition. We have strengthened our outreach efforts to enhance the recruitment of minorities to the program. This includes leveraging relationships we have forged with Historically Black Colleges and Universities in Alabama through our R25 DAP program “Summer Undergraduate Experience in Genomic Medicine (SURE-GM)” and with the Muscogee (Creek) Nation. Finally, we have adapted a program evaluation approach initially developed for SURE-GM to provide formal evaluation of our T32 Genomic Medicine Training Program.

项目摘要 UAB-HUDSONALPHA基因组医学培训计划是四年前成立的 将遗传学和基因组学整合到医学实践中的领导者。我们已经招募了研究员 参加定制的教育培训和购买至关重要的医学博士学位，博士学位或药品学位 UAB或Hudsonalpha的研究。该教育计划基于一系列能力，这些能力为 具有知识和技能的实习生是一名独立的基因组医学研究人员。每个学员 还完成了一种基因组医学实践，可为诊所和临床实验室提供暴露， 一个教育外展项目，一个探索创业职业机会的机会， 负责研究和严格性和可重复性的负责任培训。学员 作为个性化的一部分 发展计划。在UAB和Hudsonalpha举行的会议包括研究半货币，基因组 测序案例审查会议，分子肿瘤板和每月基因组医学 会议，为所有学员提供了一个基础和共同的平台。所有学员参加年度 NHGRI培训会议并介绍海报或平台演示文稿，并介绍他们的工作 在UAB进行的一项正在进行的工作中。受训者的进度在两年一年的书面报告中受到监控， 与计划联合指导者与每个学员和导师会面。几项创新 自四年前该计划成立以来就已经成立了。这些包括一个月 基因组医学会议和企业家实践；后者利用强者 Hudsonalpha与Hudsonalpha校园内的生物技术公司的关系。在 为了提高我们招募MD的能力，我们忘记了与UAB部门的关系 手术和医学系都有，均具有使居民追求两个的计划 或在他们的培训过程中进行更多的研究。我们还添加了介绍演讲 关于基因组医学基础知识的系列，以确保所有学员都配备了基本技能 基因组医学，包括数据管理和共享。所需的教育 研究中的严格性和可重复性也是一个新的补充。我们加强了我们的外展工作 增强少数群体招募该计划。这包括利用我们的关系 通过我们的R25 DAP计划，在阿拉巴马州建立了历史上的黑人学院和大学 “夏季本科基因组医学（肯定GM）的经验”，并与Muscogee（Creek）一起 国家。最后，我们已经改编了一种最初为确定GM开发的程序评估方法 提供我们T32基因组医学培训计划的正式评估。