Predoctoral Program in Biophysics

生物物理学博士前课程

• 批准号: 10628233
• 负责人: Yong Xiong
• 金额: $ 63.66万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10628233
• 关键词: Biophysics; pre-doctoral; programs

Project Summary The goal of the Yale Biophysics Training Program (BTP) is to equip predoctoral trainees with the intellectual and research foundations to become future leaders at the forefront of biophysical and biomedical sciences. The proposed BTP leverages the strengths of our previous 34 year-long program in biophysics training while incorporating substantial new focuses to adapt to the rapidly evolving research enterprise. The BTP is a PhD- track program that offers training in a wide range of biological systems and biophysical techniques to enable understanding the mechanisms of life processes at the molecular level. The BTP combines rigorous research training in a highly interactive environment and a thorough academic program in biophysics with diverse opportunities for career and skill development. The program takes advantage of the deep and diverse biophysics applicant pool at Yale as well as the extraordinary research strengths of 43 faculty trainers from many departments including Molecular Biophysics and Biochemistry (MB&B), Chemistry, Pharmacology, Immunology, and Cell Biology. BTP Program Directors Yong Xiong and Elsa Yan work together closely to oversee the program and together with four additional faculty, constitute the BTP Executive Committee, which develops new initiatives, evaluates program success based on internal and external reviews, and oversees trainee and BTP faculty evaluations and appointments. The BTP leadership will additionally ensure that our trainees thrive within an ethical, inclusive, and safe environment. The principal training entities are the MB&B Department and the Chemistry Department. Students are admitted to the BTP either directly through the Chemistry Department or from MB&B Department through an umbrella Biological and Biomedical Sciences (BBS) Program, primarily from the Biochemistry, Quantitative Biology, Biophysics, and Structural Biology (BQBS) track. Trainees are selected for BTP appointment in year 2 based on a research focus in biophysics. BTP training involves formal course work, research rotations, teaching, and qualifying exam in years 1-2, with thesis research beginning in the spring of year one. Upon joining a mentor lab, dissertation research is performed with supervision from a thesis committee comprised of at least three faculty that are familiar with the student's research topic and meet regularly to discuss progress. Training is enriched by intensive coaching in rigor, reproducibility, and responsible conduct of research, travel to major biophysics meetings, extensive outreach, mentoring, and diversity engagement, and numerous opportunities for collaboration and interaction. We are also developing special assessment tools and surveys to measure trainee development and guide future improvements. All trainee outcomes will be deposited into an easily accessible databank on the BTP website. The training resources at Yale and the dedicated commitment to training by the mentors, facilitate the BTP goal to produce the next-generation leaders in science. The BTP requests 12 training positions to appoint 6 second-year and 6 third-year students per year.

项目概要 耶鲁大学生物物理学培训计划（BTP）的目标是为博士前培训生提供知识和技能 研究基金会成为生物物理和生物医学科学前沿的未来领导者。这 拟议的 BTP 利用了我们之前长达 34 年的生物物理学培训计划的优势，同时 纳入大量新的重点，以适应快速发展的研究事业。 BTP 是一个博士项目 跟踪计划，提供广泛的生物系统和生物物理技术培训，使 在分子水平上了解生命过程的机制。 BTP 结合了严谨的研究 在高度互动的环境中进行培训，并提供全面的生物物理学学术课程 职业和技能发展的机会。该计划利用了深入而多样的生物物理学 耶鲁大学的申请人库以及来自许多国家的 43 名教师培训师的非凡研究实力 部门包括分子生物物理学和生物化学（MB&B）、化学、药理学、免疫学、 和细胞生物学。 BTP 项目总监熊勇和严艾莎密切合作，监督该项目 并与另外四名教员一起组成 BTP 执行委员会，负责制定新举措， 根据内部和外部审查评估项目的成功，并监督实习生和 BTP 教员 评估和任命。 BTP 领导层还将确保我们的学员在良好的环境中茁壮成长 道德、包容和安全的环境。主要培训实体是 MB&B 部门和 化学系。学生可直接通过化学系或 通过生物和生物医学科学 (BBS) 项目，主要来自 MB&B 部门 生物化学、定量生物学、生物物理学和结构生物学（BQBS）方向。练习生已选拔 基于生物物理学的研究重点，在第二年任命 BTP。 BTP培训涉及正规课程 第一至第二年的工作、研究轮换、教学和资格考试，论文研究于春季开始 第一年的。加入导师实验室后，论文研究是在论文的监督下进行的 委员会由至少三名熟悉学生研究主题并定期举行会议的教师组成 讨论进展情况。通过对严谨性、可重复性和负责任行为的强化指导，培训内容更加丰富 研究、参加主要生物物理学会议、广泛的外展、指导和多样性参与，以及 大量的合作和互动机会。我们还正在开发特殊的评估工具和 衡量学员发展并指导未来改进的调查。所有学员成果将被存入 进入 BTP 网站上易于访问的数据库。耶鲁大学的培训资源和专门的 导师对培训的承诺，促进 BTP 目标培养下一代科学领导者。 BTP 要求设立 12 个培训职位，每年任命 6 名二年级学生和 6 名三年级学生。