Research Projects Core

研究项目核心

• 批准号: 10628977
• 负责人: Walter I Silva
• 金额: $ 17.37万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10628977
• 关键词: Affect; Agreement; Alcohols; Alzheimer' s Disease; Area; Award; Behavior; Biological Models; Brain; Centers of Research Excellence; Core Facility; Development; Dimensions; Disease; Educational workshop; Electrophysiology (science); Entrepreneurship; Environment; Equipment; Evaluation; Evolution; Experimental Models; Fostering; Funding; Funding Agency; Goals; Government; Grant; Health; Individual; Industry; Infrastructure; Institution; Investigator-Initiated Research; Legal patent; Measures; Methodology; Modality; Modeling; Modernization; Nature; Nerve Tissue; Nervous System; Neurodegenerative Disorders; Neuronal Plasticity; Neurosciences; Neurosciences Research; New Agents; Outcome; Parkinson Disease; Participant; Phase; Pilot Projects; Population; Productivity; Publications; Puerto Rico; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Proposals; Scientist; Series; Small Business Innovation Research Grant; Small Business Technology Transfer Research; Source; Teacher Professional Development; Therapeutic; Training; Training and Education; United States National Institutes of Health; Universities; addiction; base; career development; combat; disability; equipment acquisition; higher education; instrumentation; neuroimaging; neuroinflammation; next generation; novel; novel strategies; programs; skill acquisition; success; synergism; tissue injury; tissue trauma; translational applications

Project Summary/Abstract The UPR Phases 1 and 2 CCfN significantly contributed to advancement of research in Puerto Rico. A key component has been the investigator-initiated research projects: Phase 1 and 2 Subprojects, and Phase 2 Pilot and Collaborative Seed Projects. The CCfN supported a total of 21 investigator-initiated research projects: 10 Subprojects, 4 Pilot, and 7 Seed projects. These projects impacted scientists from 5 institutions and 8 academic departments. These entailed a rich diversity of Neuroscience research themes, experimental model systems, approaches and methodology. In terms of scientific productivity COBRE-funded PIs (Subprojects, Pilots and Seeds) accounted for ~50% of the 113 total publications of the CCfN and contributed to 41% (745) of the citations total (1816). A total of ~$15M in external funds were obtained by these investigators. Subprojects accounted for 52 of the 83 grants submitted (~63%) and 27 of the 48 funded (~56%). COBRE Phase 2 Pilot and Seed projects accounted for 37.4% of grants submitted and 43% of grants funded for ~$4,25M or 36.3% of the total external funds obtained by these projects. Phase 3 CCfN seeks expansion and evolution of investigator-initiated research into a Research Projects Core (RPC) that further evidences the inherent and emerging synergism between the CCfN’s Administrative Core, Neuroimaging and Electrophysiology Facilities (NIEF), and Research Projects Core. Phase 3 RPC specifically aims to: (1) continue providing support for investigator-initiated research projects in the modalities of Pilot and Seed projects. RPC will continue support of Pilots and Seed projects, with an expanded potential user population and academic institutions. Scope will also be expanded to more Neuroscience-related research themes and entrepreneurship. Most importantly, all Seed Projects funds (5K/Seed, 25K/yr, 125K complete grant cycle) and equipment purchases during the first year of each Pilot project will derive entirely from institutional commitment funds; (2) further enhance the development of COBRE investigators’ productivity and competitiveness by their participation in programmatic activities sponsored by the Administrative and NIEF Cores. Pilot Projects participants are required to participate in the capabilities’ enhancement activities of the Administrative CORE and other applicable NIEF education and training sessions; and, (3) sponsor the submission of Neuroplasticity and related neuroscience research grants to competitive sources of research funding, including individual, multiple-PI, program project or center grants from other NIH Institutes and Centers, or other Federal and non-Federal entities. We aim to facilitate submission of multiple-PI, program project, or center grants based on areas of research strength. Given our diversity of neuroscientists and expertise we envision their coalescence into next-level collaborative research venues. The RPC will further the programmatic goals of fostering development of researchers, enhancing competitiveness, promoting continued development of a competitive research culture, and becoming a world- recognized self-sustainable Center for Neuroplasticity with emerging translational/therapeutic applications.

项目摘要/摘要 UPR阶段1和2 CCFN显着促进了波多黎各研究的发展。钥匙 组件一直是研究人员发起的研究项目：第1阶段和第2阶段，第2阶段飞行员 和协作种子项目。 CCFN总共支持了21个研究人员发起的研究项目：10 副投射，4个飞行员和7个种子项目。这些项目影响了来自5个机构和8个学术的科学家 部门。这些需要大量的神经科学研究主题，实验模型系统， 方法和方法论。就科学生产力而言 种子）占CCFN总数113个出版物的约50％，并贡献了41％（745）的引文 总计（1816）。这些调查人员总共获得了约1500万美元的外部资金。子项目占 在提交的83个赠款中，有52个（〜63％）和48个资助的27个（〜56％）。山cor阶段2飞行员和种子项目 占提交赠款的37.4％，占赠款的43％，分别为约42.5万美元，占外部总额的36.3％ 这些项目获得的资金。第三阶段CCFN寻求研究者发起的研究的扩展和演变 进入研究项目核心（RPC），进一步证明 CCFN的行政核心，神经影像学和电生理学设施（NIEF）和研究项目核心。 第3阶段RPC专门针对：（1）继续为研究者发起的研究提供支持 试点和种子项目方式的项目。 RPC将继续支持飞行员和种子项目， 随着潜在用户人数和学术机构的扩大。范围也将扩展到更多 与神经科学相关的研究主题和企业家精神。最重要的是，所有种子项目资金 （5k/seed，25k/yr，125k完整的赠款周期）和在每个试点项目的第一年购买设备 将完全源自机构承诺基金； （2）进一步增强了毛病的发展 调查人员通过参与计划活动的生产力和竞争力 由行政和疼痛核心赞助。试点项目参与者必须参加 能力的提高行政核心和其他适用的疼痛教育的增强活动以及 培训课程； （3）赞助神经可塑性和相关神经科学研究 授予竞争性的研究资金来源，包括个人，多人PI，计划项目或 来自其他NIH机构和中心或其他联邦和非联邦实体的中心赠款。我们的目标 促进基于研究力量领域的多PI，计划项目或中心赠款的提交。给出 我们的神经科学家和专业知识的多样性，我们将它们的合并视为下一级合作研究 场地。 RPC将进一步促进研究人员发展的计划目标 竞争力，促进竞争性研究文化的持续发展，并成为一个世界 - 公认的自我维持神经可塑性中心，并具有新兴的翻译/治疗应用。