Cancer Prevention and Control Research Program

癌症预防与控制研究计划

• 批准号: 10627509
• 负责人: Timothy L. Lash
• 金额: $ 5.44万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-07 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627509
• 关键词: Adherence; Adolescent; Affect; American Cancer Society; Area; Award; Behavior Therapy; Behavioral; Behavioral Sciences; Biological; Biological Markers; Biometry; Brain; Cancer Burden; Cancer Center Support Grant; Cancer Control; Cancer Control Research Program; Cancer Etiology; Cancer Patient; Cancer Survivor; Cancer Survivorship; Cardiovascular Diseases; Caring; Catchment Area; Centers for Disease Control and Prevention (U.S.); Childhood; Collaborations; Communities; Community Outreach; DNA; Data; Discipline; Discipline of Nursing; Disparity; Economics; Environment; Environmental Exposure; Epidemiology; Exposure to; Funding; Goals; Health; Healthcare; Human Papilloma Virus Vaccination; Individual; Inequity; International; Intervention; Journals; Knowledge; Late Effects; Leadership; Malignant Neoplasms; Medicine; Mission; Oncology; Outcome; Patient Outcomes Assessments; Peer Review; Policies; Population; Population Research; Prevention Research; Primary Care; Public Health; Public Health Schools; Publishing; Quality of Care; Quality of life; Recurrence; Research; Research Activity; Research Personnel; Research Training; Resource Sharing; Risk Factors; Risk Reduction; Rural; School Nursing; Scientist; Societies; Soot; Strategic Planning; Survivors; Symptoms; System; Technology; Underrepresented Populations; Universities; Weight Gain; biobehavior; burden of illness; cancer care; cancer diagnosis; cancer epidemiology; cancer prevention; cancer risk; career; community engaged research; community engagement; health equity; health organization; human disease; improved; innovation; learning community; medical schools; member; neoplasm registry; next generation; prevent; programs; recruit; reduce tobacco use; social; success; survivorship; symptom management; therapy development; tobacco control; vaccine acceptance; ward; weight gain prevention

PROJECT SUMMARY/ABSTRACT CANCER PREVENTION AND CONTROL PROGRAM The Cancer Prevention and Control (CPC) Program of Winship Cancer Institute of Emory University (Winship) coordinates and promotes all cancer prevention and control-related research activities within the center. The goal of CPC Program is to generate knowledge through innovative research and learning from the community, that will transform cancer prevention and care and reduce the cancer burden in Winship’s catchment area, the state of Georgia, and beyond. CPC has four scientific themes: (1) Cancer Epidemiology - to achieve high quality surveillance of the cancer burden and identify risk factors such as biological, behavioral, social and policy factors, and environmental exposures, to inform targeted interventions and strategies to reduce cancer risk in Georgia; (2) Interventions - focus on HPV vaccination uptake, individual behavioral interventions to reduce tobacco use and to prevent weight gain, and policy and systems-level changes with the ultimate goal of broad-scale implementation of effective strategies; (3) Cancer Survivorship and Symptom Management - focus on treatment- related early effects, including patient-reported outcomes, biobehavioral changes in the brain, childhood and adolescent cancer survivors transition to primary care, and late effects such as cardiovascular disease, which substantially affect the quality-of-life of cancer patients and survivors; and (4) Quality of Cancer Care - to conduct population-based research that describes, interprets, and predicts the impact of health care interventions and other factors on adherence to care, quality of cancer care, inequities in care, and outcomes. Under the leadership of Timothy L. Lash, DSc, MPH (leader) and Mylin Torres, MD (co-leader), CPC includes 53 core members representing 16 different departments within the School of Medicine, Nell Hodgson Woodruff School of Nursing, and Rollins School of Public Health at Emory University. This diverse membership furnishes a rich research training environment for the next generation of cancer researchers. CPC engages in ongoing interactions with Community Outreach and Engagement (COE) to inform research on catchment area priorities and actively engages in promoting biomedical scientific careers for under-represented groups. This highly collaborative group of researchers published 1,074 cancer-relevant scientific articles during the current funding period. Of these, 275 (26%) were intra- and 290 (27%) were inter-programmatic collaborations and 779 (73%) represented a collaboration with an external academic organization. 144 (13%) were published in journals with an impact factor of ≥ 10. As of end of 2021, CPC members held $14.5 million in annual total cancer-relevant research funding, of which $11.3 million is peer-reviewed (78%) and $8.6 million (59%) was awarded directly from NCI. Funding from NCI increased from $4.4 million in 2016 to $8.6 million in 2021. Notable new funding includes an R01 to support the addition of recurrence surveillance to the Georgia Cancer Registry ($3.7M total, R01CA234538, Ward/Lash), and renewed Centers for Disease Control and Prevention (CDC) funding of the Emory Prevention Research Center (U48DP006377, Kegler), focused on cancer prevention in rural Georgia.

项目摘要/摘要 预防癌症和控制计划 埃默里大学Winship癌症研究所（Winship）的癌症预防与控制计划（CPC）计划 坐标并促进中心内的所有预防癌症预防和与控制相关的研究活动。 CPC计划的目标是通过对社区的创新研究和学习来产生知识， 这将改变预防癌症的预防和护理，并减少Winship集水区的癌症燃烧， 佐治亚州及以后的状态。 CPC具有四个科学主题：（1）癌症流行病学 - 以实现高质量 监视癌症的癌症并确定危险因素，例如生物，行为，社会和政策因素， 和环境暴露，以告知有针对性的干预措施和降低佐治亚州癌症风险的策略； （2）干预措施 - 专注于HPV疫苗接种摄取，个人行为干预措施以减少烟草使用 并防止体重增加，政策和系统级别的变化，以大规模的最终目标 实施有效的策略； （3）癌症生存和症状管理 - 专注于治疗 - 相关的早期影响，包括患者报告的结果，大脑的生物行为变化，童年和 青少年癌症存活过渡到初级保健，以及诸如心血管疾病之类的晚期作用， 实质上影响癌症患者和幸存者的生活质量； （4）癌症护理的质量 - 进行 基于人群的研究描述，解释和预测医疗保健干预措施的影响 遵守护理，癌症护理质量，护理中的不平等和结果的其他因素。在领导下 DSC的Timothy L. Lash，MPH（领导者）和医学博士Mylin Torres（共同领导者），CPC包括53个核心成员 内尔·霍奇森·伍德拉夫护理学院代表医学院内的16个不同部门， 和埃默里大学的罗林斯公共卫生学院。这位潜水员的会员资格提供了丰富的研究 下一代癌症研究人员的培训环境。 CPC与 社区宣传与参与（COE），以告知有关集水区优先事项的研究 从事代表性不足的群体促进生物医学科学职业。这个高度协作的小组 在当前资助期间，研究人员发表了1,074篇与癌症相关的科学文章。其中275 （26％）是内部和290（27％）是策略间的合作，779（73％）代表 与外部学术组织合作。 144（13％）发表在具有影响力的期刊上 ≥10的系数。截至2021年底，CPC成员的年度总癌症总研究持有1450万美元 经过同行评审的1,130万美元（78％）和860万美元（59％）的资金是直接从NCI授予的。 NCI的资金从2016年的440万美元增加到2021年的860万美元。值得注意的新资金包括 R01支持在佐治亚州癌症注册表中加入复发率（总计370万美元） R01CA234538，病房/睫毛）和疾病控制与预防中心（CDC）的资金 Emory预防研究中心（U48DP006377，Kegler），重点介绍佐治亚州农村的癌症预防。