IGF::OT::IGF - METABOLITE STANDARDS SYNTHESIS CENTERS; PP 7/15/13-7/14/14; FY13;

IGF::OT::IGF - 代谢物标准品合成中心；

• 批准号: 8755788
• 负责人: HERBERT SELTZMAN
• 金额: $ 67.06万
• 依托单位: RESEARCH TRIANGLE INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-15 至 2018-07-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8755788
• 关键词: Address; Area; Citric Acid Cycle; Consultations; Contractor; Contracts; Disease; Funding; Goals; Label; Metabolic Pathway; Pathway interactions; Production; Research; Services; Sterols; Techniques; United States; United States National Institutes of Health; amino acid metabolism; good laboratory practice; lipid metabolism; metabolomics; new therapeutic target; programs

The NIH Common Fund has identified Metabolomics as one of the cross-cutting research areas that can potentially have wide ranging impact on our understanding of disease mechanisms and identifying novel therapeutic targets. In order to increase metabolomics research capacity in the United States, the NIH Common Fund has developed a multi-component Program to help overcome current challenges. This requirement is aimed at addressing one of the challenges, namely the lack of high quality and authentic standards for identification, characterization and quantitation of metabolites visualized through currently available analytical techniques. The goal is to increase the repertoire of chemically identifiable metabolites to achieve greater coverage of the metabolome.

美国国立卫生研究院共同基金已将代谢组学确定为交叉研究领域之一，可能对我们对疾病机制的理解和确定新的治疗靶点产生广泛的影响。为了提高美国的代谢组学研究能力，NIH 共同基金制定了一项多组成部分的计划，以帮助克服当前的挑战。这一要求旨在解决挑战之一，即缺乏通过当前可用的分析技术可视化的代谢物的鉴定、表征和定量的高质量和可靠的标准。目标是增加化学可识别代谢物的库，以实现代谢组的更大覆盖范围。