Multidisciplinary Research Training in Gastroenterology and Hepatology

胃肠病学和肝病学多学科研究培训

• 批准号: 10621459
• 负责人: randy s longman
• 金额: $ 8.11万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10621459
• 关键词: Gastroenterology; Hepatology; Interdisciplinary Study; Research Training

PROJECT SUMMARY The successful sequencing of the human genome and the evolution of human health services research in the post-genomic era have offered unprecedented opportunities to transform patient care in digestive diseases. Over the past decade, Weill Cornell Medicine (WCM) has made major investments in biomedical research, as well as research training and infrastructure. This is a new application from WCM that requests support for the research training of four clinical and non-clinical postdoctoral fellows in a multidisciplinary research training program (MRTP) in Gastroenterology and Hepatology, with WCM providing funding for an additional training slot. The objective is to recruit outstanding candidates with solid foundations in basic science and train them to apply their knowledge and skills towards addressing important clinically unmet needs in the prevention, diagnosis, and treatment of patients with digestive diseases. MRTP trainees will receive program support for two years during which they will follow a structured and rigorous postdoctoral training program. The MRTP will be a joint effort of 28 eminent preceptors from WCM, Memorial Sloan Kettering Cancer Center (MSKCC) and the Rockefeller University (RU), which constitute a dense network of collaborative researchers, who are international leaders in fields directly relevant to gastroenterology and hepatology. These preceptors have been organized into 3 themed units of research training: gastrointestinal malignancies, liver diseases and regeneration, and mucosal immunology and inflammation. These training units will enable the development of content-specific educational programming, as well as increase the efficiency administration within the training program. Oversight will be provided by a Research Training Executive Committee consisting of the Program Director and 2 Associate Program Directors, who will also serve as leaders of the training units, as well as 2 additional members who will provide specific guidance on clinical/epidemiologic research and on achieving and maintaining diversity within the training program. We have also assembled an outstanding roster of internal and external advisory board members with a mandate to evaluate the program and provide specific recommendations to improve both its quality and efficiency. The MRTP's highly personalized training program will include 1) individual development plans; 2) rigorous research training; 3) hands-on experience in cutting- edge methodologies; and 4) an integrated curriculum. Trainees will further benefit from the extensive institutional resources of WCM, MSKCC and RU. Based upon the growth in interest in our fellowship programs, we anticipate a substantial pool of highly qualified clinical and non-clinical candidates for the proposed MRTP, which will maintain a strong diversity focus. Through its rigorous, structured and highly personalized curriculum, this new training program seeks to train future leaders in digestive disease research who are prepared to translate their findings towards improving patient care in the United States.

项目摘要 人类基因组的成功测序以及人类健康服务研究的演变 基因组时代提供了前所未有的机会，可以改变消化疾病的患者护理。 在过去的十年中，Weill Cornell Medicine（WCM）对生物医学研究进行了重大投资，因为 以及研究培训和基础设施。这是WCM的新应用程序，请求支持 多学科研究培训中的四个临床和非临床博士后研究员的研究培训 胃肠病学和肝病学的计划（MRTP），WCM为额外的培训提供资金 投币口。目的是招募具有基础科学扎实基础的杰出候选人，并培训他们 运用他们的知识和技能来满足预防中重要的临床未满足需求， 诊断和治疗消化系统疾病。 MRTP受训人员将获得计划支持 两年之久，他们将遵循结构化和严格的博士后培训计划。 MRTP会 成为来自WCM，纪念Sloan Kettering Cancer Center（MSKCC）和 洛克菲勒大学（RU）构成了一个密集的合作研究人员网络，他们是 领域的国际领导者与胃肠病学和肝病直接相关。这些受体有 被组织成3个主题研究培训单位：胃肠道恶性肿瘤，肝病和 再生，粘膜免疫学和炎症。这些培训单位将使 特定于内容的教育计划，并提高培训中的效率管理 程序。监督将由由该计划组成的研究培训执行委员会提供 董事和2名副计划主任，他们还将担任培训单位的领导者，以及2个 其他成员将提供有关临床/流行病学研究以及实现和实现和 在培训计划中保持多样性。我们还汇集了一个出色的内部名册 和外部顾问委员会成员授权评估该计划并提供具体 提高其质量和效率的建议。 MRTP高度个性化的培训计划 将包括1）个人发展计划； 2）严格的研究培训； 3）实践实践经验 - 边缘方法； 4）集成课程。学员将进一步受益于广泛的 WCM，MSKCC和RU的机构资源。基于对我们的奖学金计划的兴趣增长， 我们预计拟议的MRTP的高度合格的临床和非临床候选者将有大量资金库， 这将保持强大的多样性重点。通过其严格，结构化和高度个性化的 课程，这个新的培训计划旨在培训未来的消化疾病研究领导者 准备将他们的发现转化为改善美国的患者护理。

项目成果

Remote monitoring of cognition in cirrhosis and encephalopathy: future opportunity and challenge.

• DOI: 10.1007/s11011-022-01134-x
• 发表时间: 2023-06
• 期刊: Metabolic brain disease
• 影响因子: 3.6

Future Therapies of Hepatic Encephalopathy.

• DOI: 10.1016/j.cld.2024.02.002
• 发表时间: 2024-05
• 期刊: Clinics in liver disease
• 影响因子: 5.1
• 作者: Adam P Buckholz;Robert S Brown

Practices and Perceptions of Living Donor Liver Transplantation, Nondirected Donation, and Liver Paired Exchange: A National Survey.

• DOI: 10.1002/lt.26384
• 发表时间: 2022-05
• 期刊: LIVER TRANSPLANTATION
• 影响因子: 4.6
• 作者: Kaplan, Alyson;Rosenblatt, Russell;Jackson, Whitney;Samstein, Benjamin;Brown, Robert S., Jr.
• 通讯作者: Brown, Robert S., Jr.