Problem-to-Product Team Entrepreneurship and Active Mentoring (P2P-TEAM) Graduate Training Program

问题到产品团队创业与主动指导（P2P-TEAM）研究生培训计划

• 批准号: 10620850
• 负责人: Jennifer S. Brodbelt
• 金额: $ 17.44万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10620850
• 关键词: Entrepreneurship; Mentors; Training Programs

Project Summary Our proposed predoctoral training program “Problem-to-Product Team Entrepreneurship and Active Mentoring” (P2P-TEAM) embraces a team science approach to research training, with an emphasis on entrepreneurial skills and professional development. The program will train the next generation of students to flourish in scientifically diverse teams and embrace an entrepreneurial perspective that will benefit the many graduate students in STEM fields who transition into industrial careers, as well as those pursuing academic or government career paths. The program revolves around the formation of interdisciplinary teams, which serve as the nuclei for pursuing advanced research projects related to the overarching theme of theranostics, a new approach to personalized medicine combining targeted therapy and diagnosis. The program will engage students in team-based collaborative projects and encourage entrepreneurial efforts that build directly from translational impact (i.e., prospects for technology transfer and commercialization). The team-based collaboration model is designed to increase accountability, develop peer networks and support systems, and motivate students to see their individual research efforts in the context of solving bigger problems with potentially translational payoffs, while the emphasis on entrepreneurship is designed to foster innovation and develop an understanding of the business world and industry practices. The program is planned for two trainees in the first year, then a steady-state of five trainees in subsequent years. The duration of each appointment is 2 years. Key programmatic features of the P2P-TEAM program include (i) collaborative research, (ii) entrepreneurial training, and (iii) professional development. The training program has 5 overarching goals: (1) facilitate the development of interdisciplinary peer teams, (2) improve scientific communication, (3) encourage an entrepreneurial perspective and business acumen not typically fostered in traditional graduate programs, (4) develop project management skills, and (5) enhance professional training (soft skills). Specific activities include training in translation of research problems into products; participation in professional development, statistical informatics, and entrepreneurship courses; activities to build networking and scientific communication skills; creation of an annual prospectus; and engagement in industrial internships. Industrial mentors will provide insight into the business aspects related to assessment of technology development arising from the collaborative research projects. The frontier field of theranostics provides avenues for both basic and applied research projects, as well as natural translation to commercialization opportunities, making it an ideal focus of the proposed training program. Because of its interdisciplinary and translational research approach, our program will be an avenue for recruiting and retaining highly innovative graduate students from diverse backgrounds.

项目摘要 我们提出的培训前培训计划“问题到产品团队的创业和积极指导” （P2P团队）采用团队科学方法进行研究培训，重点是企业家技能 和专业发展。该计划将培训下一代学生在科学上浮动 多元化的团队并拥护一种企业家的观点，将使STEM中的许多研究生受益 过渡到工业职业以及追求学术或政府职业道路的领域。 计划围绕跨学科团队的形成，这些团队是追求的核心 高级研究项目与Theranostics的总体主题有关，这是一种个性化的新方法 结合靶向疗法和诊断的医学。该计划将吸引学生参与基于团队 合作项目并鼓励直接源于翻译影响（即 技术转移和商业化的前景）。基于团队的协作模型旨在 提高问责制，发展同行网络和支持系统，并激励学生看到他们的 在解决可能翻译的收益的情况下，个人研究工作是在解决更大问题的背景下 对企业家精神的重视旨在促进创新和发展对业务的理解 世界和行业实践。该计划计划在第一年为两名学员，然后是五个学员 随后几年的学员。每个约会的持续时间为2年。 P2P团队计划的主要程序化功能包括（i）协作研究，（ii）创业 培训和（iii）专业发展。培训计划具有5个总体目标：（1）促进 发展跨学科的同伴团队，（2）改善科学交流，（3）鼓励 企业家的观点和商业敏锐度通常不在传统研究生课程中培养，（4） 发展项目管理技能，以及（5）增强专业培训（软技能）。具体活动包括 将研究问题翻译成产品的培训；参与专业发展，统计 信息和企业家课程；建立网络和科学沟通技巧的活动； 创建年度招股说明书；和从事工业实习。工业导师将提供洞察力 参与协作引起的技术发展评估有关的业务方面 研究项目。 Theranostics的边境领域为基础研究和应用研究提供了途径 项目以及自然转化为商业化机会，使其成为该项目的理想重点 拟议的培训计划。由于其跨学科和翻译研究方法，我们的计划将 成为招募和保留来自潜水员背景的高度创新研究生的途径。

项目成果

Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein.

• DOI: 10.1016/j.chom.2022.07.016
• 发表时间: 2022-09-14
• 期刊: CELL HOST & MICROBE
• 影响因子: 30.3
• 作者: Javanmardi, Kamyab;Segall-Shapiro, Thomas H.;Chou, Chia-Wei;Boutz, Daniel R.;Olsen, Randall J.;Xie, Xuping;Xia, Hongjie;Shi, Pei-Yong;Johnson, Charlie D.;Annapareddy, Ankur;Weaver, Scott;Musser, James M.;Ellington, Andrew D.;Finkelstein, Ilya J.;Gollihar, Jimmy D.
• 通讯作者: Gollihar, Jimmy D.

Proximity-Driven DNA Nanosensors.

• DOI: 10.1149/2754-2726/ace068
• 发表时间: 2023-09-01
• 期刊: ECS sensors plus