Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda (MITHU)

乌干达艾滋病毒和艾滋病毒相关研究微生物学和免疫学培训 (MITHU)

• 批准号: 10243781
• 负责人: W. Henry Boom
• 金额: $ 29.96万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-05-01 至 2026-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10243781
• 关键词: 2019-nCoV; Address; Biomedical Research; COVID-19 pandemic; Collaborations; Diagnosis; Distance Learning; Doctor of Philosophy; Educational workshop; Epidemic; Faculty; Funding; HIV; HIV/TB; Health Sciences; Immunology; Infection; Infrastructure; Institution; Internet; Journals; Mentors; Methods; Microbiology; Molecular; Prevention; Research; Research Personnel; Research Training; Rotation; Schools; Science; Scientist; Students; Training; Training Programs; Uganda; Universities; Work; base; college; doctoral student; faculty mentor; faculty research; improved; lectures; meetings; next generation; pathogen; programs; success

Abstract (450 words; 29 lines) This competing renewal builds on the success of the first 4 yrs. of the "Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda” (MITHU) training program. MITHU addresses capacity building in basic/translational biomedical research on HIV and HIV-related complications in Uganda. Persistence of the HIV epidemic, compounded by the evolving SARS-CoV-2 (COVID-19) pandemic and other emerging infections, emphasizes the importance of lab-based research capacity in immunology and molecular microbiology for tracking, prevention, diagnosis and treatment. This capacity requires biomedical faculty at Makerere University (MU) and other institutions in Uganda to train the next generation of biomedical technicians, researchers and faculty. For this competing renewal, MITHU proposes the 5 New Aims. Aim 1. To continue MITHU's success in supporting biomedical MSc training at MU. We propose to continue MSc training as a primary Aim for this next funding cycle. The best MSc students will go on to biomedical PhD training. Aim 2. To expand Biomedical PhD Training at MU by starting a Sandwich PhD program in biomedical sciences with CWRU. We propose a Sandwich PhD where outstanding MSc students will be co-mentored by faculty from MU and CWRU, spend their first yr at CWRU for selected course work in immunology or molecular microbiology, to do lab rotations, and to select CWRU and MU mentors for their thesis project. Thesis research will begin at CWRU and will be completed at MU. This Sandwich PhD program is possible because there are now 9 biomedical research faculty in MU's School of Biomedical Sciences. Six of 9 were trained at CWRU, 2 trained at MU by the Uganda-CWRU Research Collaboration and 1 at Univ. of Wash. Aim 3. To continue mentoring of junior biomedical science faculty and providing re-entry support for returning PhD trainees as they establish themselves as biomedical faculty and researchers in Uganda. MITHU will continue to coordinate a mentoring program for junior and senior research scientists with the College of Health Sciences' NURTURE program. MITHU will also continue to provide re-entry support for PhD trainees returning to Uganda. Improved internet access has greatly improved distance-learning and intercontinental interactions, allowing for remote mentoring, lab meetings and journal clubs. Aim 4. To continue to sponsor the yearly short intensive course “Host- Pathogen interactions in HIV, TB and their complications. This popular course is attended by MU biomedical MSc, MMed and PhD students. This course is a mixture of lectures, journal clubs and workshops in which MU- and CWRU-sponsored scientists present the latest biomedical results and methods related to HIV and its complications. Aim 5. To continue to leverage for MITHU the Uganda-CWRU Research Collaboration's expertise and infrastructure for HIV and TB research for training in the biomedical sciences of HIV and its complications.

摘要（450个单词； 29行） 这种竞争的更新是基于前4年的成功。 “微生物学和免疫学培训 乌干达的艾滋病毒和与艾滋病毒相关的研究”（密苏里州）培训计划。 在乌干达的HIV和HIV相关并发症的基本/转化生物医学研究中。持久性 艾滋病毒流行，由不断发展的SARS-COV-2（COVID-19）大流行和其他出现 感染，强调基于实验室的研究能力在免疫学和分子方面的重要性 用于跟踪，预防，诊断和治疗的微生物学。这种能力需要生物医学教师 Makerere University（MU）和乌干达的其他机构培训下一代生物医学 技术人员，研究人员和教师。对于这种竞争的续约，密特提出了5个新目标。目标1 继续Mithu在MU支持生物医学MSC培训方面的成功。我们建议继续MSC培训 作为下一个资金周期的主要目的。最好的MSC学生将继续接受生物医学博士学位培训。目的 2。通过启动与生物医学科学的三明治博士学位课程扩大MU的生物医学博士培训 CWRU。我们提出了三明治博士学位 和CWRU，在CWRU上度过第一年，从事免疫学或分子微生物学的选定课程工作， 进行实验室轮换，并为其论文项目选择CWRU和MU导师。论文研究将开始 CWRU，将在MU完成。这个三明治博士课程是可能的，因为现在有9个 MU生物医学科学学院的生物医学研究教师。 9个中有6名在CWRU训练，2个训练 在乌干达 - 乌干达研究合作的MU，在大学1。华盛顿的目标3。 初级生物医学科学教师，并为返回博士学位的学员提供重新入学支持 自己是乌干达的生物医学教师和研究人员。 Mithu将继续协调心理 卫生科学学院培育计划的初级和高级研究科学家计划。 Mithu还将继续为返回乌干达的博士学员提供重新进入支持。改进的互联网 访问大大改善了距离学习和洲际互动，可以进行远程心理， 实验室会议和期刊俱乐部。目标4。要继续赞助年度简短密集课程“主持人 - HIV，结核病及其并发症中的病原体相互作用。 MU生物医学参加了这项流行的课程 MSC，MMED和博士生。本课程是讲座，期刊俱乐部和研讨会的混合物，其中 CWRU赞助的科学家提出了与艾滋病毒及其有关的最新生物医学结果和方法 并发症。目标5。继续利用乌干达 - 乌干达研究合作的密特 艾滋病毒和结核病研究的专业知识和基础设施，用于艾滋病毒生物医学及其生物医学科学培训 并发症。