Transdisciplinary Research in Energetics and Cancer (TREC) Training Grant

能量学和癌症跨学科研究 (TREC) 培训补助金

• 批准号: 10270423
• 负责人: Melinda L Irwin
• 金额: $ 31.72万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10270423
• 关键词: Address; Adult; Basic Science; Body mass index; Budgets; Cancer Center; Cancer Control; Cancer Survivor; Clinical Sciences; Communities; Complex; Country; Development; Disease; Dissemination and Implementation; Educational workshop; Elderly; Extramural Activities; Faculty; Feedback; Funding; Goals; Grant; Hybrids; Immunotherapy; Incidence; Individual; Institution; Intervention; Investments; Journals; Knowledge; Low Prevalence; Low income; Malignant Neoplasms; Manuscripts; Mentors; Mentorship; Mission; Newsletter; Obesity; Obesity associated cancer; Oncology; Participant; Patient Care; Patients; Peer Review; Persons; Population; Population Sciences; Populations at Risk; Prevalence; Principal Investigator; Public Health Schools; Publications; Publishing; Research; Research Personnel; Resources; Risk Factors; Role; Scientist; Training; Training Programs; Unhealthy Diet; Work; Yale Cancer Center; anticancer research; cancer risk; career; career development; clinical care; education research; energy balance; ethnic minority population; evidence base; faculty mentor; immune function; improved; innovation; lifestyle intervention; microbiome; mortality; next generation; novel; peer coaching; physical inactivity; population health; programs; racial and ethnic; recruit; residence; rural setting; skills; training opportunity; virtual; webinar

Abstract Given the rising prevalence of obesity, poor diet and physical inactivity, known in combination as “energy balance” or “energetics”, as well as their associations with cancer incidence and mortality, innovative research, clinical care and training of scientists are needed to lower the prevalence of these risk factors and in turn, lower cancer incidence and mortality rates. In September 2020, the NCI released its Fiscal Year 2022 Budget proposal, which includes obesity and cancer as a featured scientific topic and training the next generation of cancer researchers as a key investment. With NCI R25 support from 2016-2021, we developed and offered an annual one-week, in-residence Transdisciplinary Research in Energetics and Cancer (TREC) Training Course, followed by a yearlong mentoring program, that focused on energy balance and cancer research across the cancer control continuum. The overall goals of this Program were to educate, train and mentor 100 early career investigators, called TREC Fellows, from diverse academic backgrounds (i.e., basic, clinical and population sciences) in transdisciplinary research in energetics and cancer. For the first four years of TREC, we admitted and trained 97 Fellows from 57 different institutions. We are in our 5th year of our TREC Program and expect to recruit 20 more Fellows, for a total of 117 Fellows completing the TREC Training Program. TREC Fellows have published 270 manuscripts in peer-reviewed journals, with 62 published manuscripts including the TREC Fellow as first or senior author and including a TREC Faculty and/or Fellow as co-author. Since completing the Program, TREC Fellows have received 31 extramural grants, as principal investigator. Building upon the strengths of the previous five years but responsive to additional opportunities for training and further dissemination of the course, the goals of our competitive renewal are: 1) to offer a hybrid TREC Training Program with virtual TREC Faculty-led programs before the in-person workshop focused on increasing content knowledge; 2) followed by a 5-day in-person workshop focused on the Fellows’ research, networking and professional development; and 3) year-long mentorship between the Fellow and Faculty Mentor and Peer Mentor. Led by Dr. Melinda Irwin and drawing from the resources of the Yale School of Public Health, Yale Cancer Center, and ~20 expert TREC Faculty from across the country and 100+ TREC Fellow alumni from around the world, our TREC Program is innovative in that currently no training opportunity exists that focuses on energetics and cancer research. Our goal is to continue the TREC mission of training scientists to develop a cadre of well-trained, diverse researchers. The overall impact of this program will be defined by the degree to which TREC Fellows produce innovative research approaches and discoveries, thereby accelerating the dissemination and implementation of evidence-based approaches into everyday practice and patient care, in turn improving the health of the population at risk for cancer as well as cancer survivors.

抽象的 鉴于肥胖症的患病率上升，饮食不良和身体不活跃，被称为“能量 平衡”或“能量学”，及其与癌症发病率和死亡率，创新研究的关联， 需要对科学家进行临床护理和培训，以降低这些危险因素的患病率，然后降低 癌症事件和死亡率。 2020年9月，NCI发布了2022财政年度的预算 提案，其中包括肥胖和癌症作为特色科学主题，并培训下一代 癌症研究人员是一项关键投资。在2016 - 2021年的NCI R25支持下，我们开发并提供了 年度一周的一周居住跨学科研究，用于癌症和癌症（TREC）培训课程， 其次是一个为期一年的心理计划，重点是能量平衡和癌症研究 癌症控制连续性。该计划的总体目标是早期教育，训练和心理100 从潜水员学术背景（即基本，临床和 人口科学）在能量和癌症的跨学科研究中。在TREC的头四年， 我们被录取并培训了来自57个不同机构的97名研究员。我们正处于TREC计划的第五年 并希望再招募20名研究员，总共有117名研究员完成TREC培训计划。 TREC研究员在同行评审的期刊上发表了270份手稿，有62份发表的手稿 包括TREC研究员为第一或高级作家，包括TREC教职员工和/或作为合着者。 自从完成该计划以来，TREC研究员已获得31个校外补助，作为首席调查员。 基于过去五年的优势，但要响应额外的培训机会和 进一步传播该课程，我们竞争性更新的目标是：1）提供混合TREC 在面对面的研讨会之前，通过虚拟TREC主导的计划进行培训计划 增加内容知识； 2）随后进行为期5天的面对面研讨会，重点是研究员的研究， 网络和专业发展； 3）同伴与教职员工之间的长期精神 导师和同伴导师。由梅琳达·欧文（Melinda Irwin）博士领导，并从耶鲁公立学校的资源中汲取 健康，耶鲁癌症中心和来自全国各地的约有20位专家TREC教师和100多个TREC研究员 来自世界各地的校友，我们的TREC计划具有创新性，因为目前没有培训机会 这重点介绍了能量学和癌症研究。我们的目标是继续培训科学家的TREC任务 开发训练有素的潜水研究人员的干部。该程序的总体影响将由 TREC研究员在何种程度上产生创新的研究方法和发现，从而 加速在每天的实践中加速和实施基于证据的方法和 患者护理又改善了处于癌症风险和癌症生存风险的人群的健康状况。