Mentoring and Research in Biobehavioral Aspects of Pediatric Pain

小儿疼痛生物行为方面的指导和研究

• 批准号: 10598517
• 负责人: LAURA E SIMONS
• 金额: $ 19.54万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10598517
• 关键词: Adolescent; Affective; Award; Caring; Characteristics; Child; Childhood; Clinical; Clinical Trials; Cognitive; Collaborations; Communication; Coupled; Data; Data Analyses; Dedications; Development; Disabled Children; Ensure; Ethical Issues; Evaluation; Family; Focus Groups; Funding; Future; Health; Health Services Accessibility; Healthcare; Intervention; Interview; Leadership; Legal; Mentors; Mentorship; Methods; Mid-Career Clinical Scientist Award (K24); Musculoskeletal Pain; Neurosciences; Outcome; Pain; Pain management; Parents; Participant; Patients; Pediatric Research; Personal Satisfaction; Persons; Physical therapy; Physicians; Process; Provider; Psychology; Recovery; Refractory; Research; Research Methodology; Research Personnel; Resources; Scientist; Sentinel; Site; Teenagers; Time; Training; Translating; United States National Institutes of Health; Work; Youth; biobehavior; biopsychosocial; career; career development; chronic musculoskeletal pain; chronic pain; clinical care; cohort; digital health; evidence base; expectation; experience; human subject; improved; improved outcome; innovation; multidisciplinary; multimodality; neglect; neuroimaging; next generation; opioid epidemic; patient engagement; patient oriented; patient oriented research; recruit; response; skills; success; theories; virtual; years lived with disability

Project Summary The overall objective of this K24 application is to expand my current patient-oriented research (POR) and mentoring to integrate patient engagement from research to dissemination of care to improve the biobehavioral care of youth with chronic MSK pain. This award will provide the crucial protected time to enhance my quality and quantity of mentoring of junior investigators focused on POR including current K awardees, future T-32 fellows, and clinical fellows (physician and psychology). My currently supported POR encompasses translating targeted biopsychosocial assessments into mechanistically informed treatment approaches for optimal clinical care, coupled with pain neuroscience psychology that leverages experimental and neuroimaging methods to gain a mechanistic understanding of cognitive and affective processes that coalesce with function in children with chronic pain and their parents. All projects leverage the ubiquity of digital health to enhance patient access and reach. Our lab has world-leading expertise in theory- and mechanism-oriented research for patients and their families. The new direction of research to be supported through this award focuses on gaining new expertise in scientifically rigorous qualitative and codesign methods to partner with patients and their families across all stages of research. This application proposes two studies with significant mentoring opportunities within my long- term research objective to improve the health and well-being of youth with chronic pain. Study 1 characterizes the lived experience of youth with musculoskeletal (MSK) pain seeking, completing, and reflecting on pain care. Study 2 aims to codesign an optimization of our evidence-based graded exposure treatment for adolescents with chronic MSK pain and their parents, GET Living. The K24 builds on my previous research, leverages existing cohorts and data, adds new training, and solidifies collaborations with leaders in patient participatory research and qualitative data analysis to provide effective mentorship to the next generation of POR pediatric pain scientists. With support from the K24 award, I will enhance my mentoring capacity and I will work to enhance my career development with activities relevant to my mentees, my research, and my professional development. Specifically, I plan to deepen my understanding of qualitative data methods and analysis and patient participatory research methods. Moreover, I will dedicate time to ensure continued training in legal and ethical issues associated with research on human subjects and clinical trials and strengthen my professional leadership skills. The proposed studies provide the ideal context for enhancing mentorship opportunities via hands-on training and scientific development in the biobehavioral aspects of pediatric chronic pain applying patient-centered methods. With dedicated time and training from the K24, I will be better equipped to mentor the next generation of POR pediatric pain scientists and weave a patient-centered approach into all research from inception to execution.

项目概要 此 K24 应用程序的总体目标是扩展我当前的以患者为导向的研究 (POR) 和 指导将患者参与从研究到传播护理相结合，以改善生物行为 护理患有慢性 MSK 疼痛的青少年。这个奖项将为我提高素质提供关键的保护时间 重点关注 POR 的初级研究者的指导数量和数量，包括当前的 K 获奖者、未来的 T-32 研究员和临床研究员（医生和心理学）。我目前支持的 POR 包括翻译 将有针对性的生物心理社会评估纳入机械知情的治疗方法中，以实现最佳临床 护理，结合疼痛神经科学心理学，利用实验和神经影像方法 获得对与儿童功能相结合的认知和情感过程的机械理解 患有慢性疼痛和他们的父母。所有项目都利用无处不在的数字医疗来增强患者的可及性 并达到。我们的实验室在面向患者和机制的理论和机制研究方面拥有世界领先的专业知识 他们的家人。该奖项支持的新研究方向侧重于获得新的专业知识 采用科学严谨的定性和协同设计方法，与各个领域的患者及其家人合作 研究阶段。该申请提出了两项​​研究，在我的长期研究中具有重要的指导机会 学期研究目标是改善患有慢性疼痛的青少年的健康和福祉。研究 1 的特点 患有肌肉骨骼 (MSK) 疼痛的青少年寻求、完成和反思疼痛护理的生活经历。 研究 2 旨在共同设计优化我们针对青少年的循证分级暴露治疗 患有慢性 MSK 疼痛的患者及其父母，GET Living。 K24 以我之前的研究为基础，利用了现有的 队列和数据，增加新的培训，并巩固与患者参与研究领域领导者的合作 和定性数据分析，为下一代 POR 儿科疼痛提供有效指导 科学家。在K24奖的支持下，我将增强我的指导能力，并努力提高我的水平 通过与我的学员、我的研究和我的专业发展相关的活动来实现职业发展。 具体来说，我计划加深对定性数据方法和分析以及患者参与的理解 研究方法。此外，我将花时间确保法律和道德问题方面的持续培训 与人体研究和临床试验相关，并增强我的专业领导技能。 拟议的研究为通过实践培训增加指导机会提供了理想的背景 应用以患者为中心的小儿慢性疼痛生物行为方面的科学发展 方法。凭借 K24 的投入时间和培训，我将能够更好地指导下一代 POR 儿科疼痛科学家的团队，并将以患者为中心的方法融入到从开始到实施的所有研究中 执行。