Comprehensive Mechanisms in Reproductive Sciences

生殖科学综合机制

• 批准号: 10615873
• 负责人: STEPHANIE A. PANGAS
• 金额: $ 41.72万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10615873
• 关键词: Reproductive Sciences

Project Summary and Abstract Our program goal is to train talented young scientists for research-intensive and research-related careers in reproductive biology. Baylor College of Medicine is a long-standing leader in reproductive biology research. Predoctoral and postdoctoral trainees receive mentored training in biomedical research and career development to obtain skills necessary for a variety of career paths. The predoctoral program combines state-of-the-art training in premier reproductive biology laboratories along with didactic learning. Postdoctoral fellows attend courses and seminars alongside their research training. Both will have structured committees for research and career advising that include a formal oral presentation. Trainee mentorship is guided by program-specific Individual Development Plans (IDP), developed in conjunction with the mentor and a core executive committee member. Activities to enhance skills in teaching, clinical/translational work, and entrepreneurship, is offered by BCM and neighboring collaborative institutions within the world's largest medical center. Program specific activities include a mentored journal club, an annual mini-symposium, research advisory committees, NRMN modules for mentor-mentee training, formal critiques of oral communications, assistance with development of fellowship applications, and individual career planning programs. These programs are supplemented with training in responsible conduct of research and a novel “ethics in reproductive health learning unit” specifically designed for this proposal. The 13 faculty members have been selected for contemporary research interests in reproductive biology and are currently supported by over $14 million in funding with $6 million in NICHD funding alone (43% of total PI funding). Their research areas fall squarely within the mission of NICHD, and includes studies of key reproductive biology proteins, normal and pathophysiology of male and female reproductive tissues, genetic and environmental factors that affect fertility, and translational research (male contraceptive development and developmental origins of adult disease). The training faculty use cutting edge approaches to study reproductive processes using genetic models, patient samples, in vitro models, and clinical data. Our program is designed for three predoctoral students and four postdoctoral fellows. We plan to support trainees for two years with an option to compete for a third year. Due to the long-standing reproductive biology research program at BCM and an active national recruiting strategy, we currently have a strong applicant pool in our training labs from which to select trainees, including pre- and postdoctoral trainees from UR groups. In total, our program provides necessary skills and experience to prepare the next generation of scientists for successful and diverse careers in reproductive biology.

项目摘要和摘要 我们的计划目标是培训有才华的年轻科学家，从而从事研究密集型和研究有关的职业 在生殖生物学中。贝勒医学院是生殖生物学研究的长期领导者。 托管前和博士后学员接受了生物医学研究和职业发展的指导培训 获得各种职业道路所需的技能。专用计划结合了最先进的培训 在主要的生殖生物学实验室以及教学学习中。博士后研究员参加课程， 下水道以及他们的研究培训。两者都有结构化的研究和职业咨询委员会 其中包括正式的口头陈述。受训者的精神训练以特定于计划的个人发展为指导 计划（IDP）与心理和核心执行委员会成员一起开发。活动 BCM及其邻近提供了提高教学，临床/翻译工作和企业家精神的技能 世界上最大的医疗中心内的合作机构。计划特定的活动包括一个问题 期刊俱乐部，年度迷你群岛，研究咨询委员会，NRMN心理委员会模块 培训，口头通信的正式批判性，协助发展奖学金申请以及 个人职业计划计划。这些计划补充了负责任的培训 研究和专门为该建议设计的新颖的“生殖健康学习部门的伦理”。 13 已选中教职员工的当代生殖生物学研究兴趣，并且是 目前，仅由600万美元的NICHD资金提供了超过1400万美元的资金（占PI总额的43％） 资金）。他们的研究领域直接属于NICHD的任务，包括对关键生殖的研究 生物学蛋白，雄性和女性生殖组织的正常和病理生理学，遗传和 影响生育能力和翻译研究的环境因素（男性避孕性发展和 成人疾病的发展起源）。培训教师使用尖端方法来研究生殖 使用遗传模型，患者样品，体外模型和临床数据的过程。我们的计划是为 三名学生和四名博士后研究员。我们计划支持学员两年 竞争第三年。由于BCM的长期生殖生物学研究计划， 积极的国家招聘策略，我们目前在培训实验室中有一个强大的应用程序池 精选的学员，包括UR团体的学前和博士后学员。我们的计划总共提供 必要的技能和经验，为下一代科学家做好准备，以实现成功和多元化的职业 在生殖生物学中。