Advanced Research Training in the Biology of the Inner Ear and Related Systems

内耳及相关系统生物学高级研究培训

• 批准号: 10617170
• 负责人: Ruth Anne Eatock
• 金额: $ 3.35万
• 依托单位: MARINE BIOLOGICAL LABORATORY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10617170
• 关键词: Acceleration; Address; Affect; Age; American; Area; Atmosphere; Auditory; Automobile Driving; Biological; Biological Models; Biology; Central Nervous System; Chalk; Clinical; Collaborations; Communication; Communities; Complex; Development; Developmental Cell Biology; Education; Educational Curriculum; Educational process of instructing; Enrollment; Environment; Equilibrium; Faculty; Feedback; Fostering; Foundations; Functional disorder; Genetic; Goals; Health; Hearing; Hearing problem; Human; Institution; Instruction; Investigation; Knowledge; Laboratories; Labyrinth; Learning; Mentors; Methods; Modeling; Molecular; Participant; Pathway interactions; Patients; Population; Postdoctoral Fellow; Problem Solving; Research; Research Personnel; Research Project Grants; Research Training; Science; Scientific Inquiry; Scientist; Sensory; Shoulder; Side; Site; Structure; Students; System; Talents; Technical Expertise; Techniques; Time; Training; Translating; Translations; Underrepresented Populations; Underrepresented Students; Work; career; career development; design; economic impact; education research; equilibration disorder; experience; gene therapy; graduate student; hearing impairment; improved; innovation; instructor; interest; laboratory curriculum; laboratory experience; lateral line; lectures; marine; neural; neural prosthesis; neurophysiology; next generation; peer networks; programs; recruit; response; role model; socioeconomics; stem cell biology; theories; tool; translational progress; undergraduate student; Acceleration; Address; Affect; Age; American; Area; Atmosphere; Auditory; Automobile Driving; Biological; Biological Models; Biology; Central Nervous System; Chalk; Clinical; Collaborations; Communication; Communities; Complex; Development; Developmental Cell Biology; Education; Educational Curriculum; Educational process of instructing; Enrollment; Environment; Equilibrium; Faculty; Feedback; Fostering; Foundations; Functional disorder; Genetic; Goals; Health; Hearing; Hearing problem; Human; Institution; Instruction; Investigation; Knowledge; Laboratories; Labyrinth; Learning; Mentors; Methods; Modeling; Molecular; Participant; Pathway interactions; Patients; Population; Postdoctoral Fellow; Problem Solving; Research; Research Personnel; Research Project Grants; Research Training; Science; Scientific Inquiry; Scientist; Sensory; Shoulder; Side; Site; Structure; Students; System; Talents; Technical Expertise; Techniques; Time; Training; Translating; Translations; Underrepresented Populations; Underrepresented Students; Work; career; career development; design; economic impact; education research; equilibration disorder; experience; gene therapy; graduate student; hearing impairment; improved; innovation; instructor; interest; laboratory curriculum; laboratory experience; lateral line; lectures; marine; neural; neural prosthesis; neurophysiology; next generation; peer networks; programs; recruit; response; role model; socioeconomics; stem cell biology; theories; tool; translational progress; undergraduate student

PROJECT ABSTRACT Inner ear dysfunction and the associated problems with hearing and balance affect about 30 million Americans and that number is expected to grow as the population ages. Despite the enormous socioeconomic impact, however, hearing and balance are the most poorly understood of all the senses. One significant reason for this gap in our knowledge is the technical difficulties unique to inner ear research that are a discouraging barrier to new investigators. To address this challenge, we have designed an ambitious three-week course, the Biology of the Inner Ear (BIE) course, to train new investigators in advanced research approaches to the biology of hearing and balance. In each course, 18 students are taught by a team of leading scientists and clinicians. The course will be held in the summers of 2021, 2023 and 2025 at the Marine Biological Laboratory (MBL) in Woods Hole, MA. For the intervening summers of 2022 and 2024, we plan on-site orientation programs for faculty from under-represented groups or who are hearing impaired, with the goals of increasing the diversity of faculty role models at the BIE course and attracting a greater diversity of students. The BIE course was first offered in 2007 and thereafter biennially through 2019. Each course was very well-received by students and faculty, and their feedback provided successive improvements, culminating in the present curriculum. Using the focused approach that typifies other highly successful MBL courses, BIE is designed to meet specific needs of new researchers in auditory and vestibular science. The course will continue to enroll a class comprising graduate students, postdoctoral researchers, clinician-scientists, and established investigators entering the field for the first time. These talented students will be provided with instruction and hands-on laboratory training in cutting-edge, rigorous techniques and specialized methods that are unique to investigations of the inner ear and auditory, vestibular, and lateral line systems. Through lectures, research seminars, roundtable discussions, tutorials, and informal interactions as students and instructors work side-by- side in the laboratory, the BIE course will foster the development of the students as investigators and provide the opportunity to establish long-lasting mentoring relationships. These interactions will emphasize problems, concepts, and theories that are driving current research; innovative approaches; and strategies to translate discoveries into meaningful improvements in human health. BIE is designed to enhance the pipeline of talented, highly motivated scientists entering the field, providing instruction that will challenge them and help them undertake independent and original research, and introducing them to networks within the hearing and balance community that will encourage their career development. This training will advance the pace of scientific discoveries and promote their translation into treatments that improve the lives of those suffering from hearing and balance disorders.

项目摘要 内耳功能障碍以及听力和平衡的相关问题影响约3000万美国人 随着人口年龄的增长，这一数字有望增长。尽管有巨大的社会经济影响，但 但是，听力和平衡是所有感官中最了解的。一个重要的原因 我们所知的差距是内耳研究所特有的技术困难，这是一个令人沮丧的障碍 新调查人员。为了应对这一挑战，我们设计了一个雄心勃勃的三周课程，即生物学 内耳（BIE）课程，以培训新的研究人员采用高级研究方法的生物学生物学 听力和平衡。在每门课程中，有18名学生由一组主要的科学家和临床医生教授。 该课程将在2021年，2023年和2025年的夏季举行。 马萨诸塞州伍兹霍尔。对于2022年和2024年的夏季，我们计划现场定位计划 来自代表性不足的团体或听力障碍的教师，其目标是增加多样性 在BIE课程中的教师榜样，并吸引了更多的学生。 Bie课程是第一个 于2007年及其2019年两年一次提供。每门课程都受到学生和 教师及其反馈提供了连续的改进，最终在本课程中达到了最终。使用 Bie旨在满足特定的专注于其他非常成功的MBL课程的重点方法 新研究人员在听觉和前庭科学方面的需求。该课程将继续参加课程 包括研究生，博士后研究人员，临床医生和成熟的研究人员 第一次进入该领域。这些才华横溢的学生将得到指导和动手 尖端，严格技术和专业方法的实验室培训是独有的 对内耳和听觉，前庭和侧线系统的调查。通过讲座，研究 当学生和讲师并排工作时，研讨会，圆桌讨论，教程和非正式互动 在实验室中，BIE课程将促进学生作为调查人员的发展，并提供 建立长期指导关系的机会。这些互动将强调问题， 概念和正在推动当前研究的理论；创新的方法；和翻译策略 发现人类健康的有意义改善。 bie旨在增强 才华横溢，积极进取的科学家进入该领域，提供将挑战他们并提供帮助的指导 他们进行独立和原始研究，并将其介绍给听证会内的网络 平衡社区，这将鼓励他们的职业发展。这项培训将提高 科学发现并将其转化为治疗，以改善那些患有苦难的人的生活 听力和平衡障碍。