Collaborative Hub for Emerging Adult Recovery Research (CHEARR)

新兴成人康复研究合作中心 (CEARR)

• 批准号: 10589466
• 负责人: Kristyn Zajac
• 金额: $ 190.38万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-30 至 2025-09-29
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10589466
• 关键词: Abstinence; Advocacy; Age; Applications Grants; Area; Assessment tool; Biomedical Research; Capital; Caring; Clinical; Clinical Trials; Collaborations; Communities; Complement; Connecticut; Consultations; Coupled; Data; Decision Making; Development; Education; Effectiveness; Employment; Ensure; Face; Fellowship; Formulation; Fostering; Funding; Future; Goals; Health; Health Services Research; Heterogeneity; Home visitation; Housing; Independent Living; Infrastructure; Internships; Intervention; Lead; Literature; Measurement; Measures; Mental Health; Mental disorders; National Institute of Drug Abuse; Neighborhood Health Center; Outcome; Outpatients; Persons; Pharmaceutical Preparations; Phase; Pilot Projects; Play; Psychometrics; Recovery; Recovery Support; Research; Research Activity; Research Personnel; Risk; Risk Factors; Science; Services; Social support; Specialist; Students; Subgroup; Telephone; Training; Underrepresented Populations; United States National Institutes of Health; Validation; Work; addiction; age group; base; care systems; community based participatory research; community setting; cost; effectiveness study; efficacy evaluation; emerging adult; evidence base; experience; indexing; mHealth; mortality; multidisciplinary; opioid epidemic; opioid use; opioid use disorder; outreach; peer; polysubstance use; premature; prevent; programs; recruit; reduce symptoms; repository; substance use treatment; symposium; tool; treatment organization

Abstract Emerging adults (ages 16-25) have been particularly impacted by the opioid crisis. Although medications are crucial for reducing mortality, return to opioid use, and other harms associated with opioid use disorder (OUD), persons in recovery who take or who have taken medications for OUDs (MOUDs) have many unmet needs and ongoing risk factors that prevent their return to full functioning and to flourishing. The recovery needs of EAs following stabilization on MOUDs are not well documented and are likely unique to this age group. EAs face developmental milestones characterized by frequent transitions and instability in education, housing, and relationships. The recovery needs of EAs taking MOUDs are further complicated by high rates of co-occurring mental health disorders, polysubstance use, and premature discontinuation of MOUDs. Recovery support services, particularly clinical continuing care delivered after a treatment episode, are likely to play a key role in the long-term management of OUD for EAs. Although such services can be found across the spectrum of real- world substance use treatment, very little high-quality research has evaluated the efficacy or effectiveness of recovery support services or continuing care specific to the needs of EAs. Further, continuing care research has been largely researcher-driven and focused on abstinence, symptom reduction, and reducing cost, rather than fostering recovery capital and the full range of outcomes valued by EAs in recovery from OUD. Genuine partnerships and collaborations are needed to ensure research on continuing care reflects the values and needs of EAs taking MOUDs. We will advance this critical but under-researched area by building a multidisciplinary, community-engaged network: The Continuing Care Hub for Emerging Adult Recovery Research (CHEARR). Our proposed team has extensive expertise in recovery support services, research with real-world substance use treatment organizations, and partnerships with agencies that serve EAs taking MOUDs. We propose three overarching goals that each provide actionable deliverables: (1) use a community-based participatory approach to develop the critical tools to conduct high-quality research in this area by creating and partnering with two community boards comprised of EAs who take or who have taken MOUD and recovery supports specialists who have expertise with EAs; (2) provide a hub of science on continuing care for EAs on multiple platforms to educate and engage the larger scientific community, communities impacted by OUD, and other key partner communities; and (3) create a trainee-to-investigator pipeline through a) a postdoctoral fellowship and student internship program and b) funding pilot studies that will produce preliminary data for NIH grant applications. In addition, the CHEARR team and community boards will partner to develop an EA-specific measure of recovery capital, a crucial tool that is currently missing from the scientific literature. Psychometric data on this measure will be collected as part of the pilot study program. Through these aims, CHEARR will foster rapid expansion of science and develop the infrastructure necessary to investigate continuing care services for EAs taking MOUD.

抽象的 新兴的成年人（16-25岁）受阿片类药物危机的影响。虽然是药物 对于降低死亡率，返回阿片类药物的使用以及与阿片类药物使用障碍（OUD）相关的其他危害至关重要， 康复中服用或服用Ouds药物（MOUDS）的人有许多未满足的需求，并且 持续的风险因素，以防止其恢复全部功能并蓬勃发展。 EAS的恢复需求 在MOUD上稳定后，没有充分的文献记载，并且可能是该年龄段的独特之处。 EAS面 发展里程碑的特征是教育，住房中频繁的过渡和不稳定 关系。 EAS的恢复需求更加复杂 心理健康障碍，多物质使用以及穆德的过早停用。恢复支持 服务，尤其是治疗情节后提供的临床持续护理，可能在 EA的长期管理。尽管可以在整个现实中找到此类服务 世界药物使用治疗，很少的高质量研究评估了 恢复支持服务或特定于EAS需求的持续护理。此外，持续护理研究已经 在很大程度上以研究人员为导向，并专注于禁欲，减轻症状和降低成本，而不是 促进恢复资本和EAS从OUD恢复中估价的全部结果。真的 需要伙伴关系和协作以确保对继续护理的研究反映价值和需求 EAS的MOUD。我们将通过建立一个多学科的， 社区参与网络：新兴成人康复研究（CHEARR）的持续护理中心。我们的 拟议的团队在恢复支持服务方面拥有广泛的专业知识，研究现实世界的研究 治疗组织，以及与EAS采用MOUDS的机构的合作伙伴关系。我们提出了三个 每个提供可行的可交付成果的总体目标：（1）使用基于社区的参与式方法 通过与两个建立和合作，开发在该领域进行高质量研究的关键工具 社区委员会由EAS组成，谁聘请了或接受过MOUD和恢复支持的专家 具有EAS的专业知识； （2）在多个平台上为EAS提供持续护理的科学枢纽以教育 并吸引更大的科学界，受Oud影响的社区以及其他主要合作伙伴社区； （3）通过a）博士后研究金和学生实习 计划和b）资助试点研究，该研究将为NIH赠款应用程序提供初步数据。另外， Chearr团队和社区委员会将合作开发特定于EA的恢复资本的度量， 当前科学文献中缺少的关键工具。有关此措施的心理测量数据将是 作为试点研究计划的一部分收集。通过这些目标，Chearr将促进科学的快速扩展 并开发基础设施，以调查持续护理服务以供EAS带走MOUD。