Enhancing efficacy of speech modification strategies for pediatric dysarthria

提高儿童构音障碍言语矫正策略的疗效

• 批准号: 10610448
• 负责人: Kristen M. Allison
• 金额: $ 15.7万
• 依托单位: NORTHEASTERN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-15 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10610448
• 关键词: Acoustics; Address; Adolescent; Affect; Articulation; Cerebral Palsy; Child; Childhood; Clinical; Clinical Management; Communication; Cues; Data; Development; Dysarthria; Effectiveness; Evidence based intervention; Intervention; Intervention Studies; Knowledge; Lead; Loudness; Measures; Methods; Modeling; Modification; Motor; Movement; Outcome; Population; Prevalence; Production; Quality of life; Research; Secondary to; Spastic Cerebral Palsy; Speech; Speech Disorders; Speech Intelligibility; Speech Sound; Stress; Task Performances; Techniques; Treatment Effectiveness; Voice; Work; comparative efficacy; evidence base; improved; individualized medicine; kinematics; novel; programs; response; skills; social engagement; successful intervention; Acoustics; Address; Adolescent; Affect; Articulation; Cerebral Palsy; Child; Childhood; Clinical; Clinical Management; Communication; Cues; Data; Development; Dysarthria; Effectiveness; Evidence based intervention; Intervention; Intervention Studies; Knowledge; Lead; Loudness; Measures; Methods; Modeling; Modification; Motor; Movement; Outcome; Population; Prevalence; Production; Quality of life; Research; Secondary to; Spastic Cerebral Palsy; Speech; Speech Disorders; Speech Intelligibility; Speech Sound; Stress; Task Performances; Techniques; Treatment Effectiveness; Voice; Work; comparative efficacy; evidence base; improved; individualized medicine; kinematics; novel; programs; response; skills; social engagement; successful intervention

PROJECT SUMMARY Dysarthria is a neuromotor speech disorder that negatively impacts functional communication and social participation for over 50% of children with cerebral palsy (CP). Despite its prevalence among children with CP, little evidence exists to guide treatment of dysarthria in children. Global speech modification strategies (e.g., using a loud voice or slow rate) have shown promise for improving intelligibility in this population; however, children with CP are heterogeneous in their communication skills and motor abilities, and they do not all benefit from these strategies. The effectiveness of speech modification strategies for children with CP is currently limited by a lack of research comparing the efficacy of different strategies and a poor understanding of how these strategies lead to intelligibility gains. The proposed research aims to address this need by comparing the efficacy of three speech modification strategies, and by identifying the “key ingredients” underlying intelligibility gains across different speech modification conditions. Specific Aim 1 will examine the effect of emphatic stress, a novel, local speech modification strategy on intelligibility and speech naturalness for adolescents with CP, compared to two global speech modification strategies (loud speech and slow rate). We hypothesize that the emphatic stress strategy will yield equivalent or greater intelligibility gains and higher naturalness ratings compared to the global loud and slow strategies. Specific Aim 2 will identify quantitative speech measures that best predict within-child changes in intelligibility across speaking conditions. We hypothesize that acoustic and kinematic measures of articulation will better predict within-child intelligibility gains than acoustic measures of task performance. The proposed research will provide information that has the potential to lead to development of a novel, emphatic stress intervention strategy for children with dysarthria. In addition, this research has important implications for improving theoretical understanding of factors that directly contribute to speech intelligibility gains, and could be leveraged to improve individualization of treatment techniques and maximize speech outcomes for children with dysarthria secondary to CP.

项目摘要 构造障碍是一种神经运动言语障碍，对功能产生负面影响 超过50％的脑瘫儿童（CP）的沟通和社会参与。 尽管在CP儿童中的患病率很少，但几乎没有证据可以指导治疗 儿童构造障碍。全球语音修改策略（例如，使用大声或缓慢的声音 速率）显示出有望提高该人群的清晰度的希望；但是，有孩子 CP的沟通技巧和运动能力是异质的，他们并非全部 从这些策略中受益。儿童语音修改策略的有效性 目前，CP的限制受到比较不同策略效率的研究的限制 对这些策略如何导致可理解性提升的不良理解。提议 研究旨在通过比较三个语音修改的效率来满足这种需求 策略，并通过确定不同不同的“关键成分”的“关键成分” 语音修改条件。具体目标1将检查强调的效果，a 小说，本地语音修改策略有关可理解性和语音自然的策略 与两种全球语音修改策略相比，患有CP的青少年（大声的语音和 速度缓慢）。我们假设强调压力策略将产生等效或更大的 与全球大声而缓慢相比，可理解性提高和更高的自然评级 策略。特定目标2将确定最能预测孩子内的定量语音措施 讲话条件之间的清晰度变化。我们假设声学和运动学 与声学测量相比 任务绩效。拟议的研究将提供有潜力的信息 导致针对患有儿童的新颖，强调压力干预策略的发展 构造障碍。此外，这项研究对改善理论具有重要意义 理解直接导致语音可理解性提升的因素，并且可能是 利用以提高治疗技术的个性化并最大化语音结果 用于构造障碍的儿童继发于CP。