Racial disparities for the effects of parental marijuana use on youth marijuana and other substance use

父母吸食大麻对青少年吸食大麻和其他药物的影响的种族差异

基本信息

批准号：
10593655
负责人：
Hongying Daisy Dai
金额：
$ 19.89万
依托单位：
UNIVERSITY OF NEBRASKA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-25 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10593655
关键词：
18 year old Adolescence Adolescent Adult African American African American population Age Behavior Brain Cannabis policy Child Chronic stress Communities Complement Counseling Data Databases Development Discrimination Disparity Drug usage Environment Ethnic Origin Ethnic Population Etiology Exposure to Family Fathers Future Goals Growth Health High School Student Hispanic Populations Household Individual Institution Intervention Interview Latino Population Legal Legal Status Link Longitudinal Surveys Marijuana Mediating Mediation Mental Health Methods Modeling Mothers Not Hispanic or Latino Outcome Parents Perception Pharmaceutical Preparations Policies Population Assessment of Tobacco and Health Prevalence Psychological Stress Race Reduce health disparities Regression Analysis Reporting Risk Risk Factors Social Change Social status Socioeconomic Status Stress Structure Substance abuse problem Surveys Testing Tobacco United States United States National Institutes of Health Youth acute stress adolescent offspring adolescent substance use drug use behavior experience health data health disparity populations illicit drug use innovation intergenerational low socioeconomic status marijuana legalization marijuana use marijuana user offspring outcome disparities parental influence peer prevent prospective protective factors psychological distress racial disparity racial minority racial population racism screening sex social disparities social norm substance use transmission process vaping

项目摘要

Project Summary Marijuana use among youth has been increasing, with considerably enlarged disparities across racial/ethnic groups. Racial minorities like African American (AA) adolescents are more likely to report marijuana use than their White peers. Marijuana use during adolescence can harm brain development and lead to other substance abuse and adverse health outcomes. In order to identify potential targets for interventions to reduce health disparities, there is a critical need to distinguish risk and protective factors for marijuana use that are specific to race and ethnicity. With a shifting legal environment for marijuana use in the United States and more adults supporting marijuana legalization, it is estimated that 8.2% of mothers and 9.6% of fathers living with adolescent offspring reported past-year marijuana use. The family environment is a major driver of youth development, and racial and ethnic families often experience greater exposure to systemic oppression (e.g., institutional and interpersonal racism, bias, and discrimination) and higher social inequality than their White peers, resulting in acute and chronic stress. Therefore, we hypothesize that parental marijuana use independently predicts offspring marijuana and other substance use, and intergenerational effects of marijuana use may be stronger among racial and ethnic families, especially among AA families. The overarching goal of this mixed-methods sequential explanatory study is to assess racial disparities in relationships between parental marijuana use and youth substance use. In Aim 1, we will leverage a longitudinally national survey with 5 waves of parent and offspring data (n≈3,272) to examine the intergenerational association between G1 marijuana use and subsequent G2 marijuana, vaping, tobacco, and other illicit drug use across distinct racial/ethnic groups (AAs, H/Ls vs. non-Hispanic Whites). In Aim 2, we will assess moderation and mediation effects from marijuana legalization status and other determinants (e.g., discrimination and psychological distress) across racial/ethnic groups. In Aim 3, we will conduct semi- structured interviews of parent marijuana users and their offspring (n≈96 each) to qualitatively examine the intersections of parent influences and policy change on youth substance use. Analyses of intergenerational and longitudinal surveys and semi-structured interviews will be fully integrated to complement each other and provide more robust findings. This study is innovative in its focus on assessing racial disparities in the intergenerational transmission of marijuana use in AAs and H/Ls, two NIH-designated health disparity populations. This study is also timely in responding to the rapidly shifting policy environment, rising marijuana use among youth and adults, and growing disparities by racial/ethnic group, with unknown etiology on the intergenerational drug use by racial/ethnic groups. The findings will inform the development of a future R01 to test tailored strategies to prevent youth marijuana and other substance use and reduce health disparities. 1

项目摘要年轻人中使用大麻的数量一直在增加，跨越跨越的差异种族/族裔。像非裔美国人（AA）青少年这样的种族少数民族更有可能举报大麻的使用比白人同龄人。青少年期间使用大麻会损害大脑发育和导致其他药物滥用和不利的健康结果。为了确定潜在目标减少健康分配的干预措施，迫切需要区分风险和保护因素大麻的特殊用途是种族和种族。随着法律环境的变化，用于大麻的使用美国和更多支持大麻合法化的成年人，估计有8.2％的母亲和9.6％与青少年后代相同的父亲报告了过去一年的大麻使用。家庭环境是主要的青年发展的驱动力，种族和族裔家庭经常经历更多的系统性接触压迫（例如制度和人际种族主义，偏见和歧视）和更高的社会不平等现象比他们的白人同龄人，导致急性和慢性压力。因此，我们假设那个父母大麻使用独立预测后代大麻和其他物质的使用，以及代际在种族和族裔家庭中，尤其是在AA家庭中，大麻使用的影响可能会更强。此混合方法的总体目标顺序剥夺研究是评估种族分布父母大麻的使用与青少年使用之间的关系。在AIM 1中，我们将利用一个纵向全国调查，有5波的父母和后代数据（N≈3,272），以检查 G1大麻使用与随后的G2大麻，Vaping，烟草和在不同的种族/族裔群体（AAS，H/LS与非西班牙裔白人）中使用的其他非法药物使用。在AIM 2中，我们将评估大麻合法化状况和其他决定者的适度和调解效应（例如歧视和心理困扰）跨越种族/族裔。在AIM 3中，我们将进行半父母大麻使用者及其后代（每个N≈96）的结构性访谈，以定性检查父母影响和政策变化对青年物质使用的交集。代际分析以及纵向调查和半结构化访谈将完全集成以相互补充，并且提供更健壮的发现。这项研究是创新的，重点是评估种族分布 AAS和H/LS中使用大麻的代际传播，两个NIH指定的健康差异人群。这项研究也及时响应快速变化的政策环境，大麻的上升在青年和成年人中使用，以及种族/族裔的分布，具有未知的病因种族/种族群体的代际药物使用。这些发现将为未来R01的发展提供信息测试量身定制的策略，以防止青年大麻和其他药物使用并减少健康分布。 1