Roadmap for America's Cancer Explorers for the 21st Century (Race 21)

21 世纪美国癌症探索者路线图（第 21 场比赛）

基本信息

批准号：
10252847
负责人：
Lalita A. Shevde
金额：
$ 41.79万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-03 至 2025-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10252847
关键词：
Abbreviations Adult Advanced Malignant Neoplasm Africa African American Alabama American Americas Area Awareness Biology Cancer Biology Cancer Death Rates Cancer Etiology Clinical Trials Communication Community Outreach Comprehensive Cancer Center Development Early Diagnosis Early treatment Education Exposure to Family Fellowship Foundations Future Generations General Population Goals Health High School Faculty High School Student Individual Institutes Internships Knowledge Mainstreaming Malignant Neoplasms Mentors Methods Minority Modeling Morbidity - disease rate NCI Center for Cancer Research Next Generation Science Standards Parents Pathway interactions Phase Positioning Attribute Prevention Program Development Race Research Research Personnel Research Training Resources Schools Science Science, Technology, Engineering and Mathematics Science, Technology, Engineering and Mathematics Education Secondary Schools Students Teacher Professional Development Testing Text Training Underrepresented Populations Underrepresented Students Universities Work Youth anticancer research base cancer health disparity career cohort community center experience high school improved innovation interest male minority communities minority student mortality next generation outreach programs science teacher skills summer internship summer research teacher twelfth grade undergraduate student underrepresented minority student university student

项目摘要

Roadmap for America’s Cancer Explorers for the 21st Century (RACE21) is an interdisciplinary program to develop a pipeline to a diverse 21st century cancer research workforce. Cancer is a primary cause of adult mortalities in the US, despite excellent advances in understanding cancer biology and innovative treatments. In Alabama, cancer is the 2nd highest cause of mortality, and cancer death rates are almost double in Alabama’s African-American (compared to White) males. One of the underlying causes of this anomaly is the lack of communication about cancer among Africa-Americans, especially within families. Also, relatively few African-American youth are seeking careers in cancer research, largely due to very little exposure to cancer biology in most of their secondary schools and their teachers’ lack of cancer biology training. Further, few informal programs excite students about careers in cancer biology. RACE21 will build an innovative and effective pipeline to cancer research careers, especially for students underrepresented in cancer research (URM) by building on 5-basic foundations: 1) The University of Alabama at Birmingham’s (UAB) outstanding O’Neal Comprehensive Cancer Center, 2) Over 200 cancer researchers, eager to mentor high school and college students to become the next generation of cancer researchers, 3) development of an innovative Undergraduate Cancer Biology Major, 4) the Center for Community OutReach Development (CORD), which will train high school biology teachers in cancer research and introduce advanced high school students to cancer research in both formal and informal settings and 5) training in communication about cancer. RACE21 employs successful methods developed at UAB, and uses them to advance cancer biology education. The pipeline starts with high school students being introduced to cancer biology through state-of-the-art experiences in the Summer Science Institute (10 URM rising seniors will be Summer Research Interns) and experiences at the GENEius lab. RACE21 will also provide intense cancer biology training to high school teachers via an annual 3-week BioTeach-Cancer training. RACE21 students (>80% URM) entering UAB’s new Cancer Biology Major will complete a paid summer internship in cancer research in their rising year 1 and 2, and in year 3 and 4 they will receive fellowships as cancer researchers. Each year 10 RACE21 students will complete the undergraduate major, with most continuing to graduate school in cancer research related areas. The Intellectual Merit of RACE21 will be in testing a pipeline that leads to increased minorities in cancer biology careers. The Broader Impacts will annually educate about 6,000 minority students, families and the public about cancer biology and launch the cancer research careers of >40 minority students.

21 世纪美国癌症探索者路线图 (RACE21) 是一个跨学科的项目癌症研究计划旨在为 21 世纪的多元化癌症研究队伍开发管道。尽管在了解癌症方面取得了巨大进展，但它仍然是美国成人死亡的主要原因在阿拉巴马州，癌症是第二大死因。阿拉巴马州非裔美国男性（与白人相比）的癌症死亡率几乎是白人的两倍。造成这种异常现象的根本原因之一是人们之间缺乏关于癌症的沟通。非裔美国人，尤其是在家庭中。此外，非裔美国青年相对较少。寻求癌症研究职业，很大程度上是因为大多数人很少接触癌症生物学他们的中学和教师缺乏癌症生物学培训。 RACE21 项目将激发学生对癌症生物学职业的兴趣。通往癌症研究职业的有效渠道，特别是对于癌症领域代表性不足的学生研究 (URM) 建立在 5 个基本基础上：1) 阿拉巴马大学伯明翰分校 (UAB) 杰出的奥尼尔综合癌症中心，2) 超过 200 名癌症研究人员，渴望指导高中生和大学生成为下一代癌症研究人员，3）开发创新的本科癌症生物学专业，4）中心社区外展发展 (CORD)，该项目将培训高中生物教师癌症研究并向高级高中生介绍癌症研究和非正式场合以及 5) RACE21 成功运用了癌症沟通培训。阿拉巴马大学开发的方法，并用它们来推进癌症生物学教育。首先通过最先进的技术向高中生介绍癌症生物学暑期科学研究所的经验（10名URM即将升入的高年级学生将参加暑期研究 RACE21还将提供深入的癌症生物学研究通过每年为期 3 周的 BioTeach-Cancer 学生培训来为高中教师提供培训。 (>80% URM) 进入 UAB 新的癌症生物学专业将完成带薪暑期实习在他们上升的第一年和第二年从事癌症研究，在第三年和第四年，他们将获得以下奖学金：每年 10 名 RACE21 学生将完成本科专业，其中大多数人继续在癌症研究相关领域攻读研究生。 RACE21 将测试一条管道，以增加癌症生物学职业中的少数群体。 Broader Impacts 每年将为约 6,000 名少数族裔学生、家庭和公众提供教育关于癌症生物学并启动超过 40 名少数民族学生的癌症研究生涯。