2021 Consensus Conference to Implement Optimal VTE Prophylaxis in Trauma

2021 年创伤中实施最佳 VTE 预防共识会议

• 批准号: 10237758
• 负责人: Todd W Costantini
• 金额: $ 2万
• 依托单位: COALITION FOR NATIONAL TRAUMA RESEARCH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-22 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10237758
• 关键词: Address; Admission activity; American; American College of Surgeons; Anesthesiology; Applications Grants; Area; Award; Caring; Clinical Research; Consensus; Critical Care; Data; Decision Making; Deep Vein Thrombosis; Development; Disease; Dissemination and Implementation; Education; Engineering; Ensure; Future; Goals; Guidelines; Health; Health Care Costs; Healthcare Systems; Hemorrhage; Hour; Injury; Measures; Medicine; Military Personnel; Mission; Morbidity - disease rate; National Heart, Lung, and Blood Institute; Neurologic; Nurses; Operative Surgical Procedures; Orthopedic Surgery; Orthopedics; Outcome; Participant; Pathway interactions; Patient-Centered Care; Patient-Focused Outcomes; Patients; Persons; Pharmacists; Pharmacology; Pharmacy facility; Preparation; Principal Investigator; Process; Professional Organizations; Prophylactic treatment; Publications; Pulmonary Embolism; Reporting; Research; Research Personnel; Research Priority; Risk; Science; Scientist; Societies; Solid; Specialist; Spinal Injuries; Surgeon; System; TBI Patients; Time; Trauma; Trauma Nursing; Trauma Research; Trauma patient; Travel; Underrepresented Minority; United States; United States National Academy of Sciences; Vision; Voice; Woman; care systems; clinical care; critical care nursing; disability; evidence based guidelines; high risk; high risk population; implementation research; improved; injured; interest; medical specialties; member; mortality; multidisciplinary; neurosurgery; novel; novel diagnostics; novel therapeutic intervention; organ injury; prevent; preventable death; programs; symposium; trauma care; trauma centers; venous thromboembolism

Program Director/Principal Investigator (Last, First, Middle): Costantini, Todd W & Haut, Elliott R The proposed 2021 Consensus Conference to Implement Optimal VTE Prophylaxis in Trauma will convene a multidisciplinary group of established and junior scientists and practitioners in an interactive forum (in-person and online) during which the current state and future of the science on venous thromboembolism (VTE) prophylaxis will be presented. VTE, which includes both deep vein thrombosis (DVT) and pulmonary embolism (PE), is a significant cause of morbidity and mortality for patients following major trauma. Improving patient outcomes by decreasing VTE rates in trauma patients will require implementation of evidence-based recommendations, optimization of current care pathways, and development of novel therapeutic strategies for pharmacologic prophylaxis in the future. The conference primary objectives are to promote research related to delivering timely pharmacologic VTE prophylaxis, to support the development of education platforms and clinical care pathways to improve implementation of current guidelines, and to develop future research objectives for VTE prophylaxis in trauma. The conference aims are to: 1) Define guidelines for VTE prophylaxis in high-risk trauma patients that are accepted by trauma clinicians, surgical subspecialists, nurses, pharmacists, and all specialists who provide care to injured patients; 2) Disseminate these guidelines to respective specialty organizations; 3) Address challenges to the dissemination and implementation of these guidelines across healthcare systems; 4) Define research priorities to measure short- and long-term outcomes for injured patients at risk for VTE, study the implementation of consensus guidelines, and investigate novel pharmacologic approaches to VTE prophylaxis; 5) Integrate the voice of injured patients and people with VTE to promote truly patient-centered care research; 6) Provide an opportunity to engage junior investigators, women, and underrepresented minorities interested in trauma and VTE to ensure the pipeline of a diverse group of investigators and spur new grant applications. To encourage attendance by junior investigators and trainees, 5 junior investigator travel awards will be made to cover travel and registration expenses. The offering of these awards will be announced through the Coalition for National Trauma Research’s member organizations (to their more than 14,000 members) and related professional organizations comprising underrepresented scientists and practitioners. Awardees will be encouraged to participate as authors in the preparation of the conference proceedings for publication. Roundtable discussions and networking activities are included in the conference agenda to facilitate interaction between junior and senior participants. The conference will align with NHLBI’s overarching strategic vision to: “Develop and optimize novel diagnostic and therapeutic strategies to prevent, treat, and cure HLBS diseases” (Obj. 5), to “Optimize clinical and implementation research to improve health and reduce disease” (Obj. 6), and to “Further develop, diversify, and sustain a scientific workforce capable of accomplishing the NHLBI’s mission” (Obj. 7). OMB No. 0925-0001/0002 (Rev. 03/2020 Appr to 02/28/2023) Page 1 Continuation Format Page

项目总监/首席研究员（最后、第一、中间）：Costantini、Todd W & Haut、Elliott R 拟议的 2021 年创伤中实施最佳 VTE 预防共识会议将召开 由资深科学家和初级科学家和从业者组成的多学科小组参加互动论坛（现场和在线） 在此期间，静脉血栓栓塞 (VTE) 预防科学的现状和未来将得到讨论 VTE 包括深静脉血栓形成 (DVT) 和肺栓塞 (PE)，是导致静脉血栓栓塞的重要原因。 通过降低 VTE 发生率来改善重大创伤后患者的发病率和死亡率。 创伤患者将需要基于证据的实施建议，优化当前的护理途径， 以及未来药物预防新治疗策略的开发。 会议的主要目标是促进与及时提供药理学 VTE 相关的研究 预防，支持教育平台和临床护理途径的发展，以改善预防措施的实施 会议旨在： 1) 制定高危创伤患者 VTE 预防指南，并得到创伤、外科手术人员的认可 亚专科医生、护士、药剂师以及所有为受伤患者提供护理的专家； 2) 将这些指南分发给各自的专业组织； 3) 解决在整个医疗保健系统中传播和实施这些指南所面临的挑战； 4) 确定研究重点，以衡量有 VTE 风险的受伤患者的短期和长期结果，研究 实施共识指南，并研究预防 VTE 的新药理学方法； 5) 整合受伤患者和 VTE 患者的声音，促进真正以患者为中心的护理研究； 6) 提供机会让初级调查员、女性和对创伤感兴趣的少数族裔参与进来 和 VTE，以确保多元化研究人员的渠道并刺激新的资助申请。 为了鼓励初级研究员和实习生参加，将颁发 5 份初级研究员旅行奖，用于支付 这些奖项的颁发将通过全国联盟宣布。 Trauma Research 的成员组织（超过 14,000 名成员）和相关专业组织 由代表性不足的科学家和从业者组成，将鼓励获奖者作为作者参与。 包括准备出版圆桌讨论和网络活动。 纳入会议议程，以促进初级和高级之间的互动。 此次会议将与 NHLBI 的总体战略愿景保持一致：“开发和优化新型诊断和 预防、治疗和治愈 HLBS 疾病的治疗策略”（目标 5），以“优化临床实施 改善健康和减少疾病的研究”（目标 6），以及“进一步发展、多样化和维持科学的研究” 能够完成 NHLBI 使命的员工队伍”（目标 7）。 OMB 编号 0925-0001/0002（修订版 03/2020 更新至 02/28/2023） 第 1 页 延续格式页

项目成果

Association between Race and Perioperative Outcomes after Carotid Endarterectomy for Asymptomatic Carotid Artery Stenosis in NSQIP.

NSQIP 中无症状颈动脉狭窄颈动脉内膜切除术后种族与围手术期结果之间的关联。

• DOI: 10.1097/xcs.0000000000000016
• 发表时间: 2022-01-01
• 期刊: JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
• 影响因子: 5.2
• 作者: Mallela, Deepthi P.;Canner, Joseph K.;Zarkowsky, Devin S.;Haut, Elliott R.;Abularrage, Christopher J.;Hicks, Caitlin W.
• 通讯作者: Hicks, Caitlin W.

Prevention of Hospital-Associated Venous Thromboembolism: A Road Map to Defect-Free Care.

预防医院相关静脉血栓栓塞：无缺陷护理路线图。

• DOI: 10.1097/qmh.0000000000000436
• 发表时间: 2023
• 期刊: Quality management in health care
• 影响因子: 1.2
• 作者: Lau,BrandynD;Shaffer,DauryneL;Kraus,PeggyS;Owodunni,OluwafemiP;Kia,MujanVarasteh;Chiochetti,SaraJ;Streiff,MichaelB;Haut,ElliottR
• 通讯作者: Haut,ElliottR