Amplifying Our Voice: Understanding HIV PrEP Promotional Messaging to CreateAuthentic PrEP Content by Men Who Have Sex with Men in the Deep South

放大我们的声音：了解 HIV PrEP 宣传信息，以创建南方腹地男男性行为者真实的 PrEP 内容

• 批准号: 10560642
• 负责人: Ronnie M Gravett
• 金额: $ 19.1万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-01 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10560642
• 关键词: AIDS prevention; Address; Adherence; Affect; Authorization documentation; Award; Awareness; Back; Behavioral Model; Characteristics; Communities; Data; Dedications; Deep South; Development; Development Plans; Disparity; Empathy; Enabling Factors; Epidemic; Ethnic Origin; Evaluation; Failure; Future; Goals; HIV; HIV diagnosis; Health; Health Services; Health behavior; Homophobia; Human immunodeficiency virus test; Image; Institutional Racism; Interview; K-Series Research Career Programs; Medical; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Methodology; Minority Groups; Newly Diagnosed; Outcome; Patient-Focused Outcomes; Phase; Physicians; Population; Populations at Risk; Predisposing Factor; Prevention strategy; Prophylactic treatment; Provider; Race; Research Personnel; Role; Sampling; Services; Sexual Health; Structure; Surveys; Tablets; Tenofovir; Testing; Text; Training; United States; United States National Institutes of Health; Voice; Work; age stratification; authority; barrier to care; black men who have sex with men; collaborative environment; community engagement; community involvement; crowdsourcing; design; digital; digital intervention; empowerment; emtricitabine; experimental study; health care service utilization; health disparity; homonegativity; human centered design; improved; innovation; male health; member; men; men who have sex with men; model design; multidisciplinary; multilevel analysis; novel strategies; pre-exposure prophylaxis; preference; prevent; prevention service; recruit; sex; sexual minority; skills; social media; social stigma; systemic barrier; therapy design; uptake

1 PROJECT SUMMARY/ABSTRACT: 2 This K23 award will allow Ronnie M. Gravett, MD, to train under multidisciplinary, expert mentorship to become 3 an independent patient-oriented outcomes researcher dedicated to improving the HIV outcomes affecting sexual 4 minority persons in the Deep South. HIV disproportionately affects men who have sex with men (MSM) in the 5 Deep South, a region in the United States with the highest burden of new HIV diagnoses. Pre-exposure 6 prophylaxis (PrEP) effectively prevents HIV acquisition among MSM, but there is a significant lag in PrEP uptake 7 and persistence in the Deep South when compared to other regions of the US. Barriers, such as systemic racism, 8 stigma, and homonegativity, prevent MSM from adequately accessing and using this effective strategy. The high 9 burden of HIV and inadequate PrEP uptake are NIH priorities that need novel strategies to address, such as 10 empowering and effective PrEP promotional strategies to increase PrEP uptake. Yet, there is a critical gap in 11 understanding HIV prevention messaging that is informed by the greater context of the intersecting identities and 12 known barriers to PrEP uptake among MSM in the Deep South. To address this gap, this project will examine 13 preferences for PrEP promotional messaging in order to create authentic and informative PrEP messages 14 through crowdsourcing, an innovative strategy wherein a group solves a common problem and the solution is 15 given back to the group. Integrating constructs of Andersen’s Behavioral Model of healthcare utilization and 16 community engagement into a human-centered design model will serve as the framework for this project. This 17 project will address the gap through the following specific aims: 1) explore preferences for PrEP messaging 18 content among MSM in the Deep South through qualitative interviews, 2) using a discrete choice experiment 19 (DCE), define the preferred attributes for PrEP messaging content to inform the format for the crowdsourcing 20 open call, and 3) compare MSM preferences for crowdsourced services to standard services to inform a digital 21 intervention designed to increase PrEP uptake among MSM in the Deep South. Crowdsourced content created 22 during this project will be compared to health authority content to show that community-derived content is 23 preferred by MSM. The training plan will combine formal coursework, intensive seminars, and expert mentorship 24 focused on the following topics: 1) quantitative, qualitative, and mixed methodologies, 2) design and conduct of 25 discrete choice experiments, and 3) crowdsourcing to create authentic PrEP promotional messaging. This K23 26 award will support the development of affirming, effective content to improve HIV prevention strategies among 27 MSM while also providing mentorship from renowned content and methodological experts, structured, 28 multidisciplinary training in a collaborative environment, and the avenue for Dr. Gravett to develop into an 29 independent physician investigator and leading expert in HIV prevention among sexual minorities in the Deep 30 South.

1个项目摘要/摘要： 2该K23奖将使医学博士Ronnie M. Gravett能够以多学科的专家精神训练成为 3一个独立的面向患者的结果研究人员，致力于改善影响性的HIV结果 南部的4个少数民族。艾滋病毒不成比例地影响与男性发生性关系的男性（MSM） 5 Deep South，一个在美国燃烧最高的HIV诊断的地区。预曝光 6预防（PREP）有效地阻止了MSM之间的HIV获取 7与美国其他地区相比，南方深处的持久性。障碍，例如系统性种族主义， 8污名和同性恋性，防止MSM充分访问和使用这种有效的策略。高 9艾滋病毒的伯恩和不足的准备吸收是NIH的优先事项，需要新颖的策略来解决，例如 10增强和有效的促销策略以增加预备力。然而，存在一个关键的差距 11了解相交身份的更大背景和 在深南部的MSM中，已知的12个已知障碍。为了解决这个差距，该项目将检查 13促销消息传递的偏好，以创建真实且内容丰富的准备消息 14通过众包，一个创新的策略，其中一个团体解决了一个共同的问题，解决方案是 15回到了小组。整合安徒生的医疗保健利用行为模型和 16社区参与以人为本的设计模型将作为该项目的框架。这 17项目将通过以下特定目的解决差距：1）探索预备消息的偏好 18通过定性访谈，深南部MSM之间的内容，2）使用离散选择实验 19（DCE），定义准备消息传递内容的首选属性，以告知众包的格式 20公开通话和3）比较众包服务的MSM偏好与标准服务的偏好，以告知数字 21旨在增加南部MSM的预备摄取的干预措施。创建了众包内容 22在该项目期间将与卫生授权的内容进行比较，以表明社区来源的内容是 23由MSM偏爱。培训计划将结合正式的课程，密集的半手和专家精神 24专注于以下主题：1）定量，定性和混合方法，2）设计和执行 25个离散选择实验，以及3）众包创建真实的准备促进消息传递。这个K23 26奖项将支持开发影响有效内容，以改善预防艾滋病毒的预防策略 27 MSM，同时还提供了著名内容和方法论专家的精神职位，结构化， 28在协作环境中的多学科培训，以及Gravett博士发展成为 29独立的物理研究者和深层性少数群体中艾滋病毒预防的领先专家 30南。