A community-based intervention to increase PrEP initiation among Black sexual minority men in Prince George's County, Maryland: Reducing internalized stigma and increasing social support

以社区为基础的干预措施，以提高马里兰州乔治王子县黑人性少数男性的 PrEP 启动率：减少内在耻辱并增加社会支持

• 批准号: 10588152
• 负责人: Rodman Emory Turpin
• 金额: $ 12.24万
• 依托单位: GEORGE MASON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-08 至 2026-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10588152
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Adherence; Affect; Area; Behavior; Bisexual; Black Populations; Black race; Church; Collaborations; Collection; Communication; Communities; County; Data; Data Analyses; Development; Drops; Economics; Education; Epidemic; Ethnography; Evaluation; Event; Evidence based intervention; Funding; Future; Gays; Geography; Goals; HIV; HIV Infections; HIV diagnosis; HIV disparities; HIV risk; HIV/AIDS; HIV/STD; Homophobia; Improve Access; Incidence; Income; Interdisciplinary Study; Intervention; Intervention Studies; Interview; K-Series Research Career Programs; Knowledge; Lead; Literature; Maryland; Mentors; Methods; Modeling; Outcome; Participant; Pathway Analysis; Population; Pre-Post Tests; Prevalence; Prevention; Research; Research Ethics; Research Personnel; Research Project Grants; Resources; Respondent; Risk; Risk Behaviors; Sampling; Science; Site; Social support; Testing; Training; United States; Washington; black men who have sex with men; career; career development; community intervention; design; ethnographic method; experience; falls; improved; innovation; internalized stigma; metropolitan; peer; peer support; pilot test; pre-exposure prophylaxis; programs; racism; recruit; research and development; resilience; rural setting; sexual minority men; skill acquisition; skills; social; social determinants; social factors; social stigma; structural determinants; suburb; therapy design; uptake

ABSTRACT My goal in pursuing a Mentored Research Career Development Award is to gain the necessary training, knowledge, and practical experience needed to become an independent investigator focused on improving access to and utilization of PrEP among Black men who have sex with men (BSMM) through social, peer- based intervention research. To continue my progress towards my career goals, I propose to conduct an intervention focused on increasing PrEP acceptability through developing and maintaining peer support and resilience to intersectional racism and homophobia among BSMM in Prince George’s County, MD. Despite a clear, well-documented need for greater uptake of PrEP among BSMM in this county, PrEP uptake among BSMM in this setting remains low, and extant literature specific to PrEP use in this setting and population is extremely limited. To address this need, I propose the following: Specific Aims: 1) Understand peer-peer interactions/exchanges and HIV prevention communications among BSMM through ethnographic qualitative observations (participant and direct) of two ongoing MPowerment models, 2) conduct qualitative in depth interviews to inform designing an intervention to reduce internalized racism, internalized homophobia and increase PrEP initiation among BSMM in PG County, and 3) pilot test a community-based intervention (130 participants) to reduce internalized racism, internalized homophobia, and HIV stigma and increase social support and PrEP initiation among BSMM in PG County, based on the MPowerment model. In addition to my specific aims, my Specific Career Development Aims are the following: 1) To develop expertise in the analysis of qualitative data, particularly related to social and structural factors, 2) to develop expertise in the collection and analysis of network data collected via respondent driven sampling, 3) to gain experience in the design, conduct, and evaluation of interventions and 4) to develop research management and professional development skills needed to lead future independent research projects. The knowledge and experience gained from the proposed research will provide me the skillset necessary to successfully compete for R01 funding to conduct a larger scale peer-focused intervention to promote PrEP acceptability and adherence among BSMM. The proposal makes significant contributions to the field in several ways, including 1) identifying barriers to PrEP acceptability among BSMM in Prince George’s County, 2) Qualitatively understand factors that may impact observed quantitative associations between barriers and PrEP use and acceptability, and 3) developing and evaluating an MPowerment intervention to improve PrEP use and acceptability in this population. My rigorous education, training, and research experience in social determinants of HIV/STI risk, collaborations with BSMM populations and organizations, proficiency with quantitative data analysis, and the expertise of my multidisciplinary research team, uniquely prepares me to conduct the proposed research and significantly contribute to HIV prevention science.

抽象的 我追求指导研究职业发展奖的目标是获得必要的培训， 知识和实践经验需要成为专注于改善的独立研究者 通过社交，同伴 - 基于干预研究。为了继续我的职业目标，我建议 干预措施致力于通过发展和维护同伴支持和 马里兰州乔治王子县的BSMM中对交叉种族主义和同性恋恐惧症的韧性。尽管有 在该县的BSMM中，清晰，有据可查的需求需要更大的准备 在这种情况下的BSMM仍然很低，并且在这种情况下进行准备的额外文献和人口是 极有限。为了满足这种需求，我提出以下建议：具体目的：1）了解对等点 BSMM之间通过人种学定性，BSMM之间的互动/交流和艾滋病毒预防通信 两种正在进行的MPowerment模型的观察（参与者和直接），2）深入进行定性 访谈以告知设计间隔以减少内在种族主义，内部恐同症和 增加PG县BSMM的准备计划，3）试点测试基于社区的干预措施（130 参与者）减少内在的种族主义，内在的同性恋恐惧症和艾滋病毒污名并增加社会 PG县BSMM的支持和准备计划，基于MPowerment模型。 除了我的特定目标外，我的特定职业发展目标是：1） 在定性数据分析中发展专业知识，特别是与社会和结构因素有关的专业知识，2） 在收集和分析通过响应驱动采样收集的网络数据的收集和分析方面发展专业知识，3） 在干预措施的设计，进行和评估方面获得经验，以及4） 管理和专业发展技能需要领导未来的独立研究项目。 从拟议的研究中获得的知识和经验将为我提供必要的技能 成功竞争R01资金，以进行更大规模的同伴干预措施以促进PREP BSMM之间的可接受性和依从性。该提案在几个领域为该领域做出了重大贡献 方法，包括1）确定乔治王子县BSMM的预期可接受性的障碍，2） 定性地了解可能影响障碍与障碍之间的定量关联的因素 预备使用和可接受性，以及3）开发和评估MAPEPATIRD干预措施以改善PREP 该人群的使用和可接受性。我在社会上进行严格的教育，培训和研究经验 艾滋病毒/STI风险的决定因素，与BSMM人群和组织的合作，熟练程度 定量数据分析以及我的多学科研究团队的专业知识，使我为我做好准备 进行拟议的研究，并为艾滋病毒预防科学做出重大贡献。