Expanding cancer research capacity in Nigeria with team science

通过团队科学扩大尼日利亚的癌症研究能力

• 批准号: 10588180
• 负责人: OLUSEGUN ISAAC ALATISE
• 金额: $ 26.81万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-08 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10588180
• 关键词: Area; Behavioral Sciences; Biometry; Cancer Patient; Caring; Clinical; Collaborations; Colorectal Cancer; Country; Development; Discipline; Discipline of Nursing; Doctor of Philosophy; E-learning; Evidence based intervention; Foundations; Goals; Health; Health Policy; Incidence; Individual; Infrastructure; Institution; Malignant Neoplasms; Medicine; Memorial Sloan-Kettering Cancer Center; Mentors; Mentorship; Nigeria; Nigerian; Nurses; Nursing Faculty; Oncology; Outcome; Physicians; Public Health; Research; Research Personnel; Research Project Grants; Research Training; Science; Solid; Teaching Hospitals; Training; Training Programs; Universities; anticancer research; cancer epidemiology; cancer therapy; clinical practice; college; design; hands on research; malignant breast neoplasm; medical specialties; meetings; multidisciplinary; programs

SUMMARY In Nigeria, cancer is a significant and growing public health threat. Given the rising incidence and poor outcomes associated with cancer in the region, the Nigerian Ministry of Health has designated cancer as a priority area for research and training. To support this, we propose a new training program – the Nigerian Cancer Research Training (NCAT) program – with the goal of increasing capacity for cancer research in Nigeria. We seek to not only strengthen the existing research enterprise but to build in- country expertise and provide a solid foundation for the development, implementation, and dissemination of evidence-based interventions that will impact public health policy, as well as clinical practice, care, and treatment for cancer patients. The NCAT program will build on existing relationships and infrastructure established over the past decade between Memorial Sloan Kettering Cancer Center (MSK) in the US, Obafemi Awolowo University (OAU) in Nigeria, and the College of Medicine/Lagos University Teaching Hospital (CMUL/LUTH) in Nigeria. We will employ a multi-level approach to strengthen research capacity for individuals (Aim 1) and institutions (Aim 2), while also enhancing broader relationships at national, regional, and global levels (Aim 3). The NCAT program will address two distinct needs for cancer research training in Nigeria: 1. a training program that can be used for clinical faculty (primarily physicians and nurses) that will not interfere with clinical/research duties, and 2. a training program to bolster the capacity of full-time PhD-level researchers in the disciplines of cancer epidemiology, behavioral sciences, and biostatistics. Trainees will be competitively selected, and we will emphasize diversity and underrepresented specialties (e.g., nursing, psycho-oncology). A multi-pronged training approach, utilizing coursework, “hands-on” research in ongoing breast and colorectal cancer studies, virtual learning, mentorship, and collaboration will be used to train a cadre of multidisciplinary Nigerian cancer researchers. After a one-year cancer research training period, NCAT trainees will be grouped into research teams and take part in team science-based training, which will include designing and conducting a collaborative mentored pilot research project in Nigeria. In addition, to enhance support for local researchers beyond the project period, we will develop cancer research training courses to be used in Nigeria, and provide mentorship and training to research administration offices at OAU and CMUL/LUTH. We will use multiple layers of trainee and project assessment to ensure that our program is meeting its ultimate goal of creating well-trained colorectal and breast cancer researchers and a sustainable pipeline for continued cancer research in Nigeria.

概括 在尼日利亚，鉴于发病率上升和贫困，癌症是一个重大且日益严重的公共卫生威胁。 该地区与癌症相关的结果，尼日利亚卫生部已指定癌症 作为研究和培训的优先领域，为了支持这一点，我们提出了一个新的培训计划—— 尼日利亚癌症研究培训 (NCAT) 计划 – 目标是提高癌症治疗能力 我们不仅寻求加强现有的研究事业，而且建立内部- 国家专业知识，为制定、实施和 传播将影响公共卫生政策以及临床的循证干预措施 NCAT 项目将建立在现有关系的基础上。 以及纪念斯隆凯特琳癌症中心在过去十年中建立的基础设施 美国 MSK（MSK）、尼日利亚奥巴费米阿沃洛沃大学（OAU）以及拉各斯医学院 尼日利亚大学教学医院 (CMUL/LUTH) 我们将采用多层次的方法。 加强个人（目标 1）和机构（目标 2）的研究能力，同时还增强 NCAT 计划将解决国家、区域和全球层面更广泛的关系（目标 3）。 尼日利亚对癌症研究培训有两个不同的需求： 1. 可用于 不会干扰临床/研究职责的临床人员（主要是医生和护士），以及 2. 加强以下学科全职博士级研究人员能力的培训计划 癌症流行病学、行为科学和生物统计学将通过竞争选拔， 我们将强调多样性和代表性不足的专业（例如护理、心理肿瘤学）。 多管齐下的培训方法，利用课程作业，对正在进行的乳房和乳腺疾病进行“实践”研究 结直肠癌研究、虚拟学习、指导和协作将用于培训一支骨干队伍 经过一年的癌症研究培训后，NCAT 获得了多学科尼日利亚癌症研究人员的认可。 学员将被分为研究小组并参加基于科学的团队培训，这将 包括在尼日利亚设计和开展合作指导试点研究项目。 为了在项目期结束后加强对当地研究人员的支持，我们将开展癌症研究 将在尼日利亚使用的培训课程，并向研究管理人员提供指导和培训 在 OAU 和 CMUL/LUTH 办事处，我们将使用多层的实习生和项目评估来进行评估。 确保我们的计划实现其最终目标，即培养训练有素的结直肠癌和乳腺癌患者 研究人员和尼日利亚持续癌症研究的可持续管道。