Biomedical Informatics

生物医学信息学

基本信息

批准号：
10580672
负责人：
David J Foran
金额：
$ 21.72万
依托单位：
RUTGERS BIOMEDICAL AND HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-03-01 至 2024-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10580672
关键词：
Address Algorithms Antibodies Antigens Archives Area Basic Science Bioinformatics Cancer Center Support Grant Cancer Detection Cancer Institute of New Jersey Caring Classification Clinical Clinical Research Clinical Trials Cloud Computing Collaborations Color Communities Consultations Data Data Analyses Data Management Resources Data Set Data Sources Development Devices Diagnosis Diagnostic Disease Progression Doctor of Philosophy Education Educational workshop Environment Exhibits Fostering Genes Genetic Genomics Goals Heterogeneity Image Informatics Information Technology Lead Leadership Machine Learning Malignant Neoplasms Maps Measures Methods Microscopy Mission Modeling Molecular Morphology Oncogenes Oncology Onset of illness Pathology Pathway interactions Patient Care Patients Performance Population Research Productivity Prognosis Quantum Dots Radiology Specialty Reproducibility Research Research Personnel Research Project Grants Resource Sharing Resources Sampling Services Slide Specimen Supercomputing System Systems Biology Technology Therapeutic Tissues Training Translational Research Tumor Suppressor Proteins anticancer research biomarker signature biomedical informatics cheminformatics clinical data warehouse data acquisition data mining design digital distributed data drug discovery experience genomic data genomic variation high dimensionality high resolution imaging imaging study improved in silico informatics shared resource innovation insight instrumentation member molecular dynamics multidimensional data multimodality next generation sequencing novel therapeutics pathology imaging patient population personalized care personalized management precision medicine prognostic programs radiological imaging screening spectrograph tool treatment response tumor

项目摘要

BIOMEDICAL INFORMATICS SHARED RESOURCE PROJECT SUMMARY/ABSTRACT As Cancer research continues to become increasingly data driven, many investigative studies underway at Rutgers Cancer Institute of New Jersey (CINJ) rely upon analysis of multi-dimensional data sets, high- resolution imaging, next generation sequencing and other information intensive technologies. The Biomedical Informatics shared resource (Bioinformatics) addresses these challenges through the use of high-throughput instrumentation, advanced data management systems, machine-learning technologies, high-performance cloud computing environments and state-of-the-art supercomputing capabilities. Under the direction of David J. Foran, PhD, the overarching mission of Bioinformatics is to provide leading- edge data acquisition and analysis tools, computational informatics expertise, data analysis, and intensive training to foster advances in research and discovery in investigative oncology. Application of these activities to genomic data from patient samples is enhancing patient care and initiating and sustaining productive collaborations among CINJ investigators and throughout the clinical and basic research community. To optimize the support we provide to our basic, clinical and population research programs Bioinformatics is organized into the following sections: Computational Imaging; Clinical and Research Information Technology (IT); Chemical Informatics and Drug Discovery; and Bioinformatics and Systems Biology.

生物医学信息学共享资源项目摘要/摘要随着癌症研究继续变得越来越多地驱动数据，许多研究性研究正在进行新泽西州罗格斯癌症研究所（CINJ）依靠对多维数据集的分析分辨率成像，下一代测序和其他信息密集型技术。生物医学信息共享资源（生物信息学）通过使用高通量来解决这些挑战仪器，高级数据管理系统，机器学习技术，高性能云计算环境和最先进的超级计算功能。在David J. Foran博士的指导下，生物信息学的总体使命是提供领先 - 边缘数据获取和分析工具，计算信息学专业知识，数据分析和密集培训以促进调查肿瘤学研究和发现的进步。这些活动的应用来自患者样本的基因组数据正在增强患者护理，启动和维持生产力 CINJ研究人员以及整个临床和基础研究社区之间的合作。优化我们为基本，临床和人口研究计划提供的支持，生物信息学是组织为以下各节：计算成像；临床和研究信息技术（它）;化学信息学和药物发现；以及生物信息学和系统生物学。