SURFACTANT POSITIVE AIRWAY PRESSURE AND PULSE OXIMETRY TRIAL IN ELBW INFANTS

ELBW 婴儿的表面活性剂气道正压和脉搏血氧饱和度试验

• 批准号: 7717880
• 负责人: DAVID K STEVENSON
• 金额: $ 0.1万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-12-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7717880
• 关键词: Air Pressure; Bronchopulmonary Dysplasia; Computer Retrieval of Information on Scientific Projects Database; Delivery Rooms; Environmental air flow; Funding; Grant; Incidence; Infant; Institution; Intratracheal Intubation; Mechanical ventilation; Oxygen; Premature Infant; Pulse Oximetry; Pulse Pressure; Research; Research Personnel; Resources; Retinopathy of Prematurity; Source; United States National Institutes of Health; surfactant

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The investigators hope to determine if the incidence bronchopulmonary dysplasia (BPD) can be reduced in premature infants by using continuous positive air pressure (CPAP) and a permissive ventilation strategy rather than automatic endotracheal intubation, surfactant administration, and conventional mechanical ventilation beginning in the delivery room. They also hope to determine if maintaining a lower oxygen saturation in these infants will reduce the incidence of significant retinopathy of prematurity (ROP).

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 研究人员希望确定是否可以通过使用持续正压通气（CPAP）和允许通气策略来降低早产儿支气管肺发育不良（BPD）的发病率，而不是在分娩开始时进行自动气管插管、表面活性剂给药和传统机械通气房间。 他们还希望确定这些婴儿维持较低的氧饱和度是否会降低严重早产儿视网膜病变（ROP）的发生率。