Enhancing Exercise Intensity, Motivation and Enjoyment for Persons with PD: Comparing Visual Feedback and Competition in A Virtual Cycling Environment (VCYCLE)

提高帕金森病患者的运动强度、动力和乐趣：在虚拟自行车环境 (VCYCLE) 中比较视觉反馈和竞争

• 批准号: 10574581
• 负责人: John Palmieri
• 金额: $ 5.27万
• 依托单位: RUTGERS BIOMEDICAL AND HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-07 至 2025-04-06
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10574581
• 关键词: Address; Adherence; Adult; Affect; Animal Model; Applied Research; Area; Attention; Autonomic Dysfunction; Behavior; Bicycling; Bradykinesia; Cardiovascular system; Central Nervous System; Clinical; Clinical assessments; Cognitive deficits; Communities; Coupled; Data; Disease; Dopamine; Dopamine Receptor; Educational process of instructing; Elderly; Elements; Emotional; Engineering; Environment; Equilibrium; Equipment; Equipment and supply inventories; Exercise; Exertion; Fatigue; Feedback; Gait; Gait abnormality; Goals; Health; Heart Rate; Human Resources; Knowledge; Laboratories; Measures; Mental Depression; Mentors; Mentorship; Modeling; Motivation; Motor; Movement Disorder Society Unified Parkinson' s Disease Rating Scale; Nerve Degeneration; Neurologic; Neuronal Plasticity; Parkinson Disease; Participant; Patients; Perception; Personal Satisfaction; Persons; Pharmacotherapy; Population; Posture; Program Accessibility; Quality of life; Recommendation; Rehabilitation therapy; Reporting; Research; Risk; Role; Scientist; Services; Severity of illness; Sleep disturbances; Speed; Stimulus; Strenuous Exercise; Students; System; Therapeutic Effect; Time; Training; Virtual and Augmented reality; Visual attention; Work; comorbidity; design; efficacy testing; exercise intensity; exercise program; exercise regimen; exercise training; experience; fitness; graduate student; head mounted display; improved; improved mobility; insight; interest; intrinsic motivation; motor control; motor rehabilitation; neuromuscular; neuromusculoskeletal; non-motor symptom; parent grant; patient population; post stroke; posture instability; programs; side effect; skills; tool; virtual; virtual environment; virtual reality; visual feedback

Project Summary In this single group study of 33 persons with Parkinson's Disease (PD, Hoehn and Yahr Stages II-III) will exercise in two virtual reality augmented bicycling conditions: visual feedback and competition. The primary purpose of the study is to determine which condition of bicycling (visual feedback or competitive) promotes a higher exercise intensity in the neuromusculoskeletal domain (measured by revolutions per minutes on the bicycle) and in the cardiovascular domain (measure by % of max. heart rate) as well as which promotes higher motivation and enjoyment (measured with the Intrinsic Motivation Inventory) and reduced perception of effort (measured with the Borg Scale). The secondary aims are to explore how personal factors (competitiveness) influence the exercise intensity, and whether visual attention can differentiate between the cycling conditions. Data will be collected in a single session consisting of clinical assessments and bicycling for ten minutes for each condition while wearing a head mounted display to interact with the virtual environment. Results from this study will inform the design of optimal exercise programs to make exercise accessible, enjoyable for persons with PD. Those programs will be tested for efficacy at improving mobility and fitness leading to well-being for persons with PD. The proposed project will be undertaken in a well-equipped laboratory under the mentorship of a sponsor with a long track record of designing virtual reality tools for persons with neurologic health conditions. The sponsor has successfully mentored dozens of graduate students including dual-degree students, training to be clinician scientists. Collaborators and contributors from diverse training backgrounds and areas of expertise will work with the sponsor and PI on this project. The PI will couple his previous training in engineering with new skills developed in applied science. The PI's training plan includes goals related to research execution and dissemination, clinical experience, teaching/mentoring, and community/professional service all of which can be realistically achieved.

项目概要 在这项针对 33 名帕金森病患者（PD、Hoehn 和 Yahr II-III 期）的单组研究中， 在两种虚拟现实增强自行车条件下进行锻炼：视觉反馈和竞争。初级 该研究的目的是确定哪种骑行条件（视觉反馈或竞争）可以促进 神经肌肉骨骼领域的运动强度更高（以每分钟转数来衡量） 自行车）和心血管领域（以最大心率的百分比衡量）以及促进更高的 动机和享受（用内在动机量表衡量）以及对努力的感知减少 （用博格量表测量）。第二个目标是探索个人因素（竞争力）如何 影响运动强度，以及视觉注意力是否可以区分骑行条件。 数据将在一次会议中收集，包括临床评估和每次骑自行车十分钟 佩戴头戴式显示器与虚拟环境交互时的情况。 这项研究的结果将为最佳锻炼计划的设计提供信息，使锻炼变得容易， 对于帕金森病患者来说很有趣。这些计划将测试其在改善活动能力和健康方面的功效 为帕金森病患者带来福祉。 拟议的项目将在赞助商的指导下在设备齐全的实验室进行 拥有为患有神经系统健康问题的人设计虚拟现实工具的长期记录。这 赞助商已成功指导了数十名研究生，包括双学位学生，培训成为 临床科学家。来自不同培训背景和专业领域的合作者和贡献者将 与赞助商和 PI 合作开展该项目。 PI 将把他以前的工程培训与新的培训结合起来 在应用科学中发展的技能。 PI 的培训计划包括与研究执行和 传播、临床经验、教学/指导和社区/专业服务，所有这些都可以 切实实现了。