Indigenous Trauma & Resilience Research Center

本土创伤

• 批准号: 10091058
• 负责人: Donald Keith Warne
• 金额: $ 211.5万
• 依托单位: UNIVERSITY OF NORTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10091058
• 关键词: Address; Advisory Committees; Age; American Indians; Assimilations; Award; Basic Science; Behavioral; Biological; Centers of Research Excellence; Cessation of life; Chippewa; Chronic Disease; Collection; Communities; Community Outreach; Core Grant; Development; Enrollment; Ensure; Epigenetic Process; Faculty; Food; Funding; Funding Opportunities; Future; Goals; Grant; Health; Health Promotion; Human Subject Research; Indigenous; Individual; Infant Mortality; Interdisciplinary Study; Link; Mentors; Methods; Monoclonal Antibody R24; Native-Born; North Dakota; Outcome; Peer Review; Personal Satisfaction; Population; Post-Traumatic Stress Disorders; Poverty; Pregnancy; Principal Investigator; Publishing; Research; Research Assistant; Research Infrastructure; Research Personnel; Research Project Grants; Risk Factors; Sampling; Scholarship; Schools; Senior Scientist; Services; Social Conditions; Stress; Suicide; Teton Sioux Indian; Training; Training Activity; Translational Research; Trauma; Tribes; Turtles; Unemployment; United States National Institutes of Health; Universities; Work; academic program; addiction; allostatic load; base; career; community based participatory research; community engagement; emotional trauma; experience; faculty research; graduate student; health disparity; health inequalities; human subject; improved; indigenous community; infrastructure development; interest; intergenerational; member; perceived stress; programs; protective factors; psychological trauma; ranpirnase; resilience; skills; success; tribal community; Address; Advisory Committees; Age; American Indians; Assimilations; Award; Basic Science; Behavioral; Biological; Centers of Research Excellence; Cessation of life; Chippewa; Chronic Disease; Collection; Communities; Community Outreach; Core Grant; Development; Enrollment; Ensure; Epigenetic Process; Faculty; Food; Funding; Funding Opportunities; Future; Goals; Grant; Health; Health Promotion; Human Subject Research; Indigenous; Individual; Infant Mortality; Interdisciplinary Study; Link; Mentors; Methods; Monoclonal Antibody R24; Native-Born; North Dakota; Outcome; Peer Review; Personal Satisfaction; Population; Post-Traumatic Stress Disorders; Poverty; Pregnancy; Principal Investigator; Publishing; Research; Research Assistant; Research Infrastructure; Research Personnel; Research Project Grants; Risk Factors; Sampling; Scholarship; Schools; Senior Scientist; Services; Social Conditions; Stress; Suicide; Teton Sioux Indian; Training; Training Activity; Translational Research; Trauma; Tribes; Turtles; Unemployment; United States National Institutes of Health; Universities; Work; academic program; addiction; allostatic load; base; career; community based participatory research; community engagement; emotional trauma; experience; faculty research; graduate student; health disparity; health inequalities; human subject; improved; indigenous community; infrastructure development; interest; intergenerational; member; perceived stress; programs; protective factors; psychological trauma; ranpirnase; resilience; skills; success; tribal community

OVERALL PROJECT ABSTRACT Indigenous populations experience significant trauma-related health disparities, including addiction, post- traumatic stress disorder, chronic diseases, infant mortality, and suicide. Many of these disparities are worse for American Indians (AIs) in the Dakotas. AI communities also contend with historical and intergenerational trauma from decades of traumatic losses and forced assimilation. Hence, we will establish the Indigenous Trauma & Resilience Research Center at UND to address the health impact of unresolved trauma and the protective factors of cultural connectedness and resilience. The Center will consist of three interrelated research projects—each led by an early career investigator and assisted by senior scientist mentors. Objectives: 1. Establish a nationally-recognized and acclaimed Indigenous Trauma & Resilience Research Center at UND with a goal to improve AI health and well-being. 2. Provide support and mentoring to the Project Leaders to enable future success in obtaining R01 funding. 3. Establish Administrative, Community Engagement & Outreach, and Human Subjects Cores that will support the Center and will provide services to strengthen research capacity to address Indigenous health. Methods: Three research projects include: (1) Historical trauma and resilience as a biological state and its association with the effects of the traditional Indigenous food chokeberry; (2) Impact of boarding school attendance on perceived stress, allostatic load and resilience; and (3) Stress and health in American Indian pregnancies. We will leverage existing assets at UND, including several Institutional Development Award (IDeA) programs. Mentoring will be provided to support the project leaders through an Administrative Core consisting of the Program Director/Principal Investigator (PD/PI), Internal and External Advisory Committees, and a group of high-level scientific Project Mentors. Each project leader will use community-based, participatory research principles and will complete the Tribal Community Engagement Training Module that was developed by the PD/PI. A Community Engagement & Outreach Core will be led by Dr. Melanie Nadeau of the Turtle Mountain Band of Chippewa Indians from ND. Cultural considerations for human subjects research and collection of biological samples will be supported by a Human Subjects Core that will provide technical assistance regarding research compliance and addressing cultural norms. Significant opportunities exist for meta-scholarship in which COBRE stakeholders will publish best and promising practices to support community-engaged human subjects research with Indigenous populations. The center will be sustainable and competitive for numerous other grant programs, including Research Project Grants (R01) and related funding.

总体项目摘要 土著人口经历了与创伤相关的重要健康分布，包括成瘾，后 创伤性应激障碍，慢性疾病，婴儿死亡率和自杀。这些差距中的许多情况更糟 对于达科他州的美洲印第安人（AIS）。 AI社区还包含历史和代际 数十年来创伤损失和强迫同化的创伤。因此，我们将建立土著 UND的创伤与韧性研究中心解决未解决的创伤的健康影响 文化联系和韧性的保护因素。该中心将由三个相互关联 研究项目 - 由早期职业调查员领导，并在高级科学家导师的协助下。 目标： 1。建立一个全国认可和广受赞誉的土著创伤与弹性研究中心 und的目标是改善人工智能健康和福祉。 2.向项目负责人提供支持和心理，以使未来获得R01资金的成功。 3。建立行政，社区参与和宣传以及将会的人类核心 支持该中心，并将为解决土著健康的强大研究能力提供服务。 方法：三个研究项目包括：（1）历史创伤和韧性作为生物状态及其 与传统的土著食品乔莓的影响相关； （2）寄宿学校的影响 参加压力，同性恋负荷和韧性； （3）美洲印第安人的压力和健康 怀孕。我们将利用UND的现有资产，包括几项机构发展奖 （想法）程序。将提供指导以通过行政核心支持项目领导者 由计划主任/首席研究员（PD/PI），内部和外部咨询委员会组成 以及一群高级科学项目导师。每个项目负责人将使用基于社区的 参与研究原则，并将完成部落社区参与培训模块 由PD/PI开发。社区参与和外展核心将由Melanie博士领导 ND的Chippewa印第安人乌龟山乐队的Nadeau。人类主题的文化考虑因素 生物样品的研究和收集将由人类对象核心支持，该核心将提供 有关研究合规性和解决文化规范的技术援助。巨大的机会 存在于元智能职位的情况下，在该职位中，cobre利益相关者将发布最佳和承诺实践以支持 社区参与的人类对土著人口的研究。该中心将是可持续的， 竞争其他众多赠款计划，包括研究项目赠款（R01）和相关资金。